Sea cucumber compound preparation, preparation method and usage formulation thereof

A sea cucumber and product technology, applied in the field of pharmaceutical preparations, can solve the problems of unclear target groups and unclear effects, and achieve the effect of improving pharmacological functions

Inactive Publication Date: 2011-04-27
DALIAN HAIYANTANG BIOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Sea cucumber compound preparations are basically blank in the market at present. There are only a few such as patent 200710114414.7 compound sea cucumber glycopeptide or

Method used

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  • Sea cucumber compound preparation, preparation method and usage formulation thereof
  • Sea cucumber compound preparation, preparation method and usage formulation thereof
  • Sea cucumber compound preparation, preparation method and usage formulation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] (1) Raw material processing: cut open the fresh sea cucumber, take out the viscera, fully clean the body wall of the sea cucumber respectively, and place them in an airtight container.

[0024] (2) Gelling: Heat the above container at 70-80°C for 20h.

[0025] (3) Vacuum freeze-drying: the sea cucumber after gelatinization is carried out freeze-drying, and moisture content is 0.1wt%

[0026] (4) Coarse crushing: coarsely crushing the freeze-dried sea cucumber. Sea cucumber powder with a fineness ranging from 10 to 300 meshes is obtained.

[0027] (5) Superfine pulverization: the coarsely pulverized sea cucumber powder is pulverized by a jet mill to obtain superfine sea cucumber powder with a pulverization fineness of 100-3000 mesh.

[0028] (6) Nano-grinding: the sea cucumber superfine powder that has been jet-milled is nano-pulverized with a high-energy ball mill, and the milling time is 4 hours.

[0029] (7) The nano sea japonicus nanopowder and the notoginseng sap...

Embodiment 2

[0033] (1) Raw material processing: cut open the fresh ginseng, take out the viscera, wash them thoroughly respectively, mince the body wall and viscera of the ginseng and place them in a closed container.

[0034] (2) Gelling: Heat the above container at 90-95°C for 6 hours.

[0035] (3) Vacuum freeze-drying: freeze-dry the sea cucumber after gelatinization, and the water content is 3wt%

[0036] (4) Coarse crushing: coarsely crushing the freeze-dried sea cucumber. Sea cucumber powder with a fineness ranging from 10 to 300 meshes is obtained.

[0037] (5) Superfine pulverization: the coarsely pulverized sea cucumber powder is pulverized by a jet mill to obtain superfine sea cucumber powder with a pulverization fineness of 100-3000 mesh.

[0038] (6) Nano-grinding: the sea cucumber superfine powder that has been jet-milled is nano-pulverized with a high-energy ball mill, and the milling time is 10 hours.

[0039] (7) The nano sea japonicus nanopowder and the notoginseng sap...

Embodiment 3

[0044] (1) Raw material processing: cut open the fresh ginseng, take out the viscera, wash them thoroughly respectively, mince the body wall and viscera of the ginseng and place them in a closed container.

[0045] (2) Gelling: Heat the above container at 100-105°C for 1 hour.

[0046] (3) Vacuum freeze-drying: freeze-dry the sea cucumber after gelatinization, and the water content is 3wt%

[0047] (4) Coarse crushing: coarsely crushing the freeze-dried sea cucumber. Sea cucumber powder with a fineness ranging from 10 to 300 meshes is obtained.

[0048] (5) Superfine pulverization: the coarsely pulverized sea cucumber powder is pulverized by a jet mill to obtain superfine sea cucumber powder with a pulverization fineness of 100-3000 mesh.

[0049] (6) Nano-grinding: the sea cucumber superfine powder that has been jet-milled is nano-pulverized with a high-energy ball mill, and the milling time is 12 hours.

[0050] (7) The nano leaf ginseng powder and the notoginseng saponin e...

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Abstract

The invention relates to a sea cucumber compound preparation, a preparation method and a usage formulation thereof. The preparation method comprises the steps of: shearing a fresh sea cucumber, taking internal organs out, respectively fully cleaning, and placing in a closed container; heating at a temperature of 70-130 DEG C and gluing for 1min-20h; freezing and drying until the water content is less than 10 percent; roughly crushing the sea cucumber until the fineness is 10-3,000mu; and carrying out superfine crushing with an airflow crushing equipment until the fineness is 100-3000mu; and finally carrying out nano crushing with a high-energy ball mill pulverizer until the fineness is 10-1,000nm. The sea cucumber compound preparation is prepared by mixing 99-80 percent by weight of nano sea cucumber powder and 1-20 percent by weight of notoginsenoside. The compound preparation of the nano sea cucumber and the notoginsenoside can greatly improve the pharmacological functions of the single formula of the sea cucumber or notoginsenoside, removes the defects brought by the single use of the sea cucumber or notoginsenoside, obtains better health care effect compared with the preparation adopting the single sea cucumber or notoginsenoside, and can be used for various health care and pharmacological applications.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations derived from mollusk extracts and plants. Background technique [0002] Sea cucumber is one of the eight delicacies of seafood in my country, and its nourishing value is recognized by people. Among them, sea cucumber polysaccharide is the most important active ingredient in sea cucumber, which has a variety of physiological activities. According to experimental studies, sea cucumber polysaccharide has a significant effect on combating cardiovascular and cerebrovascular diseases. After the sea cucumber is nano-sized, it can be directly developed, which can not only make full use of important active ingredients such as sea cucumber polysaccharides, but also make full use of sea cucumber proteins, lipids and other components. [0003] Panax notoginseng is a ginseng plant native to southern Yunnan. Its rhizome is like ginger, and it is used by folks to treat bruises, blood circula...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61K9/48A61K9/20A61K9/16A61P9/00A61P7/02A23L1/30A61K35/56A61K31/715A23L17/20A61K35/616
CPCA61K2236/39A23V2002/00A23L1/327A61K31/704A61K35/616A61K36/258A23L17/50A61P25/00A61P7/02A61P9/00A61P9/10A61K2300/00A23V2200/25A23V2250/2042
Inventor 焦健邵俊杰
Owner DALIAN HAIYANTANG BIOLOGY
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