Method for separating astragalus polysaccharide and astragalin astragaloside by ultrasonic film chromatography

A technology of astragalus polysaccharides and astragalus saponins, which is applied in the field of extraction and separation of active ingredients of medicinal plants, can solve the problems of long process time, low efficiency, and complicated steps, and achieve the effect of controllable separation process, high purity, and simple operation

Inactive Publication Date: 2011-05-04
西安保赛天恒生物技术股份有限公司
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Aiming at the current problems of extracting and separating astragalus polysaccharides and astragalosides from ast

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Take 5 kg of Astragalus mongolica medicinal material, pulverize it, extract twice with 12 times the amount of 90% ethanol and water at 70°C and 100°C, respectively, for 1.5 hours each time, and combine all the extracts. The combined filtrate was separated by BCSM-1 ultrasonic membrane separator. When the membrane flux decreased by 5%, the ultrasonic was turned on and adjusted to a weak ultrasonic state. The continuous decrease of the membrane flux could be adjusted to a strong ultrasonic state to collect the filtrate containing small molecules. The liquid is passed and concentrated, and the macromolecular polysaccharides that do not pass through the membrane are circulated and filtered to improve the purity. The circulating concentrate containing macromolecules was collected, precipitated with alcohol, and dried to obtain 431.9 grams of astragalus polysaccharides with a purity of 84.2% (as determined by the phenol-sulfuric acid method).

[0019] The supernatant in the a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a method for separating astragalus polysaccharide and astragalin astragaloside. The method is characterized by adopting the process combining the separation of an ultrasonic film separator and the separation of reversed-phase preparative column chromatography. The whole technological process is simple, quick and large in processing amount and purifies two active ingredients, namely the astragalus polysaccharide and the astragalin astragaloside, at the same time. The obtained product has high purity. The method has the advantages of simple process, high automation control degree and simple industrial application.

Description

technical field [0001] The invention belongs to a method for extracting and separating two effective components of astragalus astragalus polysaccharide and astragaloside, and belongs to the technical field of extraction and separation of effective components of medicinal plants. Background technique [0002] Astragalus is the dried root of Astragalus mongholicus (Bge.) Hsiao] or Astragalus membranaceus (Fisch.) Bge. of the leguminous plant. Astragalus membranaceus (Fisch.) Bge. Efficacy of purging pus, suppressing sores and promoting muscle growth. Modern pharmacological studies have shown that astragalus polysaccharides and astragalosides are the main active ingredients in medicinal astragalus. Aging and anti-radiation, two-way regulation of blood sugar and other effects, astragaloside also has anti-inflammatory, antihypertensive, analgesic, sedative effects, can promote the normal body's antibody production, and increase the phagocytosis rate of macrophages. At present, t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C08B37/00C07J53/00
Inventor 郭立安赵彦鼎常建华
Owner 西安保赛天恒生物技术股份有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap