Tjn molecular kit for diagnosing virulent strains of helicobacter pylori

A Helicobacter pylori and kit technology, applied in the field of molecular diagnostic kits used to detect virulent strains of Helicobacter pylori, can solve problems such as difficult to use, and achieve high reliability, consistency and probability of definite results high effect
CN102099486AInactive Publication Date: 2011-06-15UNIV DE CONCEPCION
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
UNIV DE CONCEPCION
Publication Date
2011-06-15
Estimated Expiration
Not applicable · inactive patent

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Abstract

A kit in the form of a product and a method able to detect simultaneously four genes of Helicobacter pylori (rDNAl6S Hpy), i.e. one identification gene and three virulence genes (cagA, vacAml, dupA), is disclosed. Moreover, the kit envisages the association of primers which determine the quality of extraction of the DNA (Eub gene).
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Description

Background technique

[0001] Infections caused by Helicobacter pylori are a major public health problem because their control is very expensive. This situation has led to a need for tools to detect risk factors associated with this condition. However, there are currently no commercially available microbial assays to detect virulent strains.

[0002] Since there are currently no reliable laboratory tools for the detection of H. pylori, eradication therapy for this bacterium is based only on qualitative methods, and there are no treatments or treatments to measure the virulence of H. pylori.

[0003] Existing methods only indicate the presence or absence of microorganisms, but do not reveal the nature or identity of the infecting strain. Another important aspect is that only very sporadic endoscopic studies have been performed in children, so there are very few data on infections in this age group.

[0004] According to reports worldwide, eradication therapy fails in 20% to 80...

Claims

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