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Medicament for treating rheumatoid arthritis and preparation method thereof

A technology for arthritis and rheumatoid arthritis, which is applied in the field of drugs for the treatment of rheumatoid arthritis and its preparation, and can solve problems such as destruction, narrowing of joint space, and insufficient treatment effect for patients with rheumatoid arthritis

Inactive Publication Date: 2011-08-10
杨相德 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the medicine is mild, and it is suitable for the treatment of articular surface cartilage destruction, joint space narrowing and blurring, bone erosion destruction, and subperiosteal cyst formation in mid-stage rheumatoid patients, and even articular surface fusion, fibrous or bony ankylosis, joint deformity and dislocation , the treatment effect of patients with advanced rheumatoid arthritis accompanied by symptoms such as pathological fractures is not obvious enough

Method used

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  • Medicament for treating rheumatoid arthritis and preparation method thereof
  • Medicament for treating rheumatoid arthritis and preparation method thereof
  • Medicament for treating rheumatoid arthritis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0095] [Example 1] Capsule preparation of the present invention.

[0096] A) 2 grams of Zhimaqian, 12 grams of black ants, 15 grams of Zhichuanwu, 5 grams of centipede, 6 grams of scorpion, 12 grams of Tripterygium wilfordii, 11 grams of Xugufeng, 11 grams of Chuanxiong, 14 grams of Asarum, 9 grams After drying, the traditional Chinese medicine is crushed to 100-200 mesh, soaked in water for 3-5 hours, the amount of water should not exceed the surface of the medicine, then put it in a glass jar or stainless steel bottle and steam it for 1 hour, and filter to obtain the filtrate 1. Add black sesame powder to the filtrate at a ratio of 1:2, and dry at 40-50°C to obtain dry extract material 1;

[0097] b) 14 grams of angelica, 10 grams of ginseng (white ginseng), 10 grams of Gastrodia elata, and 8 grams of Tianqi in the weight ratio are crushed to 200 mesh, and 90%-95% ethanol is added for alcohol precipitation, and the ethanol is recovered and concentrated , dried at 40-50°C to...

Embodiment 2

[0100] [Embodiment 2] Preparation of granules of medicine of the present invention

[0101] a) Weigh 2 grams of Zhimaqian, 12 grams of black ants, 5 grams of centipede, 6 grams of scorpion, 11 grams of Xugufeng, 12 grams of Tripterygium wilfordii, 14 grams of angelica, 10 grams of ginseng (white ginseng), and 10 grams of Gastrodia elata , Chuanxiong 11g, Tianqi 8g, Zhichuanwu 15g, Asarum 14g, honey 120g, set aside;

[0102] b) Dried and crushed 9 traditional Chinese medicines of Zhinong, Black Ant, Zhichuanwu, Centipede, Scorpion, Tripterygium wilfordii, Xugufeng, Chuanxiong, Asarum to 100-200 mesh, then soaked in distilled water for 3-5 hours , the amount of water is appropriate to cover the noodles, then put it in a glass jar or stainless steel bottle and seal it, steam and bake it in a steamer for 1 hour, and filter to obtain the filtrate 1. Add black sesame powder to the filtrate at a ratio of 1:2, and dry at 40-50°C to obtain dry extract raw material 1;

[0103] c) Crus...

Embodiment 3

[0106] [embodiment 3] tablet preparation of medicine of the present invention

[0107] a) Take each raw material according to the following weight proportions: 2 grams of Noxyma money, 12 grams of black ant, 5 grams of centipede, 6 grams of scorpion, 11 grams of Xugufeng, 12 grams of Tripterygium wilfordii, 14 grams of angelica, ginseng (White Ginseng) 10 grams, Gastrodia elata 10 grams, Rhizoma Chuanxiong 11 grams, Tianqi 8 grams, Zhichuan Aconitum 15 grams, Asarum 14 grams, honey 120 grams, set aside;

[0108] b) Dried Zhinony, Black Ant, Zhichuanwu, Centipede, Scorpion, Tripterygium wilfordii, Xugufeng, Chuanxiong, Asarum, crushed to 100-200 mesh, soaked in distilled water for 3-5 hours, and then Put it into a sealed upper steamer in a glass jar or a stainless steel bottle and steam it for 1 hour, filter to obtain the filtrate, mix it with black sesame powder, and dry it at 40-50°C to obtain the raw material 1 of the dry extract, which is set aside;

[0109] Crush angelica...

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Abstract

The invention discloses a medicament for treating rheumatoid arthritis and a preparation method thereof. The medicament is mainly prepared from processed semen strychni, black ant, scorpion, centipede, tripterygium wilfordii, processed radix aconiti, asarum, angelica, ginseng, pseudo-ginseng, chuanxiong rhizome, gastrodia tuber, wooly datchmanspipe herb and honey according to certain proportions by weight. The medicament can be prepared into any one of common oral preparations and can also be prepared into externally applied ointment. The medicament disclosed by the invention has the functions of relieving pain, diminishing inflammation, resisting bacteria, promoting blood circulation, dispersing pathogenic wind, activating collaterals, tonifying the kidney, invigorating the spleen, strengthening the liver, nourishing the stomach and expelling toxins. Thus, the medicament has high effect taking speed and high cure rate when used for treating rheumatoid arthritis.

Description

technical field [0001] The invention relates to a medicine for treating rheumatoid arthritis and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Rheumatoid disease is a systemic immune disease in humans, which can be divided into acute rheumatoid arthritis and chronic rheumatoid arthritis. According to its clinical characteristics, this disease belongs to the category of "arthromyopathy" in traditional Chinese medicine. There are "heat numbness", "damp heat numbness" and "heart numbness". According to the classification of "Su Wen Bi Lun", there are four numbnesses of movement, pain, movement, and heat, and subdivided into twelve numbnesses of skin, veins, muscles, tendons, bones, heart, liver, spleen, kidney, intestines, and cells. difference. Modern medicine treats acute rheumatic fever, active rheumatic arthritis, chronic rheumatoid arthritis, rheumatic myofibritis, periarthritis of shoulder, partial ...

Claims

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Application Information

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IPC IPC(8): A61K35/64A61K36/9068A61K35/32A61K36/8988A61P19/02A61P29/00A61P19/04A61K35/644A61K35/646A61K35/648
Inventor 杨相德黄明和尹华荣
Owner 杨相德
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