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Self-heated traditional Chinese medicine (TCM) emplastrum for improving stroke sequelae

A technology for post-stroke sequelae and traditional Chinese medicine sticking, which is applied to heating appliances for treatment, drug combinations, and medical formulas, etc., and can solve the problems of numerous prescriptions and insufficient simplicity

Inactive Publication Date: 2012-03-07
广东养美医药投资有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the medicine disclosed in the above patent application has the effects of promoting blood circulation and removing blood stasis, relaxing meridians and collaterals, promoting dampness and reducing swelling, and can be used to treat sequelae of apoplexy, the prescription has many flavors and is not concise enough.

Method used

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  • Self-heated traditional Chinese medicine (TCM) emplastrum for improving stroke sequelae
  • Self-heated traditional Chinese medicine (TCM) emplastrum for improving stroke sequelae

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] 1. Preparation of plaster:

[0054] Prescription of raw materials: papaya 60g, mulberry branch 60g, Caulis Spatholobus 180g, angelica 40g, red peony root 60g.

[0055] Matrix formula: 31g gelatin, 12g sodium carboxymethylcellulose, 8g polyvinyl alcohol, 88g pressure-sensitive adhesive, 24g carbomer, 250g glycerol, 250g propylene glycol, 5g kaolin, 5g zinc oxide, 9g citric acid, citric acid Sodium 33g, water 285g.

[0056] Preparation of active ingredients: add water to decoct the above five-flavored raw materials twice, add 6 times the amount of water for the first time, add 6 times the amount of water for the second time, each time for 1.5 hours, combine the second decoction, filter, and concentrate the filtrate to Thick paste with a relative density of 1.28-1.32 (measured at 60°C), dried at 80°C, pulverized into fine powder, and sieved to obtain traditional Chinese medicine extract powder.

[0057] Preparation of plaster: dissolve the prepared active ingredients in ...

Embodiment 2

[0064] 1. Preparation of plaster:

[0065] Prescription of raw materials: papaya 40g, mulberry branch 48g, Caulis Spatholobus 160g, angelica 65g, red peony root 87g.

[0066] Matrix formula: 37g gelatin, 14g sodium carboxymethylcellulose, 10g polyvinyl alcohol, 307g glycerol, 306g propylene glycol, 50g polyethylene glycol, 50g butanediol, 6g zinc oxide, 6g micronized silica gel, 29g sodium citrate , aluminum trichloride 8g, water 177g.

[0067] The preparation of active ingredient: same as embodiment one.

[0068] Preparation of plaster: dissolve the prepared active ingredients in water, add propylene glycol, glycerin, polyethylene glycol and butylene glycol and mix to obtain a mixed solution; dissolve polyvinyl alcohol in 1 / 2 of the above mixed solution, fully swell, Component 1 is obtained; sodium carboxymethyl cellulose is dissolved in 1 / 6 of the above mixed solution, and fully swelled to obtain component 2; zinc oxide and micropowder silica gel are dissolved in 1 / 6 of th...

Embodiment 3

[0075] 1. Preparation of plaster:

[0076] Prescription of raw materials: papaya 74g, mulberry branch 40g, Caulis Spatholobus 160g, angelica 52g, red peony root 74g.

[0077] Matrix formula: 40g gelatin, 17g sodium carboxymethylcellulose, 17g methylcellulose, 11g sodium polyacrylate, 11g polyvinyl alcohol, 11g polyvinylpyrrolidone, 125g pressure-sensitive adhesive, 33g carbomer, 156g glycerol, Propylene glycol 156g, micropowder silica gel 8g, citric acid 15g, sodium citrate 27g, water 373g.

[0078] The preparation of active ingredient: same as embodiment one.

[0079] Preparation of plaster: dissolve the prepared active ingredients in water, add glycerol and propylene glycol and mix to obtain a mixed solution; dissolve polyvinyl alcohol in 1 / 2 of the above mixed solution, and fully swell to obtain component 1; gelatin, carboxylate Sodium methyl cellulose, methyl cellulose, sodium polyacrylate, polyvinylpyrrolidone and pressure-sensitive adhesive are dissolved in 1 / 6 of the ...

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Abstract

The invention relates to a traditional Chinese medicine (TCM) compound preparation, and in particular relates to a self-heated TCM emplastrum for improving stroke sequelae. The emplastrum comprises a sealing bag, a plaster and a self-heated bag, wherein the plaster and the self-heated bag are wrapped in the sealing bag and are bonded together up and down; the self-heated bag comprises an air-permeable bag and chemical heating materials which are wrapped in the air-permeable bag and carry out iron oxidation-reduction reactions; and the plaster comprises a backing layer, a medicine storage layer and an anti-adhesion layer. The emplastrum is characterized in that the medicine storage layer comprises a pharmaceutically acceptable matrix and active ingredients of active pharmaceutical ingredients; and the active ingredients account for 40% of the matrix by weight and are aqueous extracts of the following active pharmaceutical ingredients by weight percent: 10-25% of pawpaw, 10-25% of mulberry twigs, 40-50% of caulis spatholobi, 5-25% of angelica and 10-25% of red paeony root. The emplastrum has the advantages of quick effect, good percutaneous absorption and definite curative effect.

Description

field of invention [0001] The invention relates to medical preparations, in particular to a traditional Chinese medicine compound preparation. technical background [0002] Stroke sequelae refer to the general term for symptoms such as crooked mouth and eyes, impaired speech, and hemiplegia left over after stroke treatment, which seriously affects the health and quality of life of patients. At present, modern medicine has no good treatment for stroke sequelae. However, Chinese medicine has obvious advantages in the treatment of stroke sequelae. Due to the high incidence of stroke sequelae, which seriously affects the quality of life of patients and their families, it is an objective need to seek a method of improving stroke sequelae that can give full play to the characteristics of traditional Chinese medicine and is popular. [0003] Due to the many and complex factors affecting stroke and stroke sequelae, multi-link and multi-level Chinese medicine compound preparations ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/732A61K9/70A61F7/03A61P9/10
Inventor 方永奇方惠新刘林薛中锋方若鸣
Owner 广东养美医药投资有限公司
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