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Preparation method of traditional Tibetan medicine composition for treating liver diseases

A composition and technology of Tibetan medicine, applied in the field of preparation of Tibetan medicine compositions, can solve the problems of slow release of active ingredients of raw medicines, affecting the absorption and utilization of active ingredients of medicines, etc., to protect thermally unstable ingredients, achieve effective enrichment, The effect of increasing the drug concentration

Active Publication Date: 2012-07-18
JINHE TIBETAN MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the preparation methods of Ganchang drugs in the prior art all adopt simple physical treatment of crushing and mixing the raw materials, and the active ingredients of the raw materials are released slowly, which seriously affects the absorption and utilization of the active ingredients of the drug. It is urgent to introduce modern preparation methods. Provide fast dissolution, onset of effect, and better absorption and utilization of Ganchang preparations

Method used

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  • Preparation method of traditional Tibetan medicine composition for treating liver diseases
  • Preparation method of traditional Tibetan medicine composition for treating liver diseases
  • Preparation method of traditional Tibetan medicine composition for treating liver diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-5

[0038] The proportioning by weight of the crude drug of the embodiment 1-5 pharmaceutical composition is as follows:

[0039] 17.6 parts of turquoise, 17.6 parts of geranium, 43.7 parts of safflower, 7 parts of saffron, 52 parts of Meconopsis, 35 parts of Ganqing Qinglan, 35 parts of Corydalis viridifera, 38.2 parts of rock extract, 17.6 parts of clove, artificial bezoar 3.5 parts, Indian Swertia 17.6 parts, Pollen melon seeds 10.5 parts, stone flower 3.5 parts, artificial musk 1.4 parts.

[0040] The original commercially available Ganchang Capsules used for comparison was the product of Jinhe Tibetan Medicine Pharmaceutical Co., Ltd.

experiment example 1

[0041] The Ganchang pharmaceutical composition used in Experimental Example 1 is the pharmaceutical composition prepared in Examples 1-5.

[0042] The DM130 type resins used in the examples and experimental examples are available from Anhui Sanxing Resin Technology Co., Ltd.; HPD600, YWD-01 type resins are available from Cangzhou Baoen Chemical Co., Ltd.; X-5, NKA, ADS-F8, LS-300 , D101 type resin Nankai University Chemical Plant is available; LSA-21LSA-40 type resin Xi'an Lanxiao Technology Co., Ltd. is available for sale.

Embodiment 1

[0043] Embodiment 1, the preparation of a kind of pharmaceutical composition capsule for the treatment of liver disease

[0044] (1) Get cloves according to the proportioning ratio of the raw material medicine, add water to 6 times the weight, adopt steam distillation, extract the volatile oil for 4 hours, collect the volatile oil to obtain the volatile oil, filter the medicinal liquid, and obtain the extract A' and the medicinal residue A;

[0045] Add the collected volatile oil into 4% by volume percent β-cyclodextrin saturated aqueous solution, the volume-to-weight ratio of volatile oil to β-cyclodextrin is 1ml:4g, under stirring conditions, keep the temperature at 50°C, stir for 4h, -4°C Refrigerate overnight, filter with suction, precipitate, and vacuum-dry at 5°C to obtain volatile oil clathrate;

[0046] (2) According to the composition ratio of the raw materials, take 7 kinds of medicinal materials including sweet orchid, safflower, meconopsis, Corydalis sylvestris, In...

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Abstract

The invention relates to a preparation method of a traditional Tibetan medicine composition for treating liver diseases, which comprises the following steps: extracting and including volatile oil, extracting with ethanol, pulverizing the medicinal materials into fine powder, forming the preparation and the like. Compared with the traditional preparation, the medicine application compliance of the patient can be obviously enhanced. The pharmaceutical preparation prepared by the method provided by the invention can implement high absorption speed, quick effect taking and high bioavailability on the premise of reserving the drug effect of the original preparation; the effective ingredient can reach to the focus position centrally; and the pharmaceutical preparation has favorable curative effect.

Description

technical field [0001] The invention relates to a preparation method of a Tibetan medicine composition, in particular to a preparation method of a Tibetan medicine composition for treating liver diseases, and belongs to the field of Tibetan medicine preparations. Background technique [0002] The liver is the metabolic center of the human body. It is one of the important organs for maintaining life. Its functional status is closely related to the health of the human body. If the liver cells are damaged, the function of the liver will be damaged, which may cause a series of inadaptable symptoms of the body. Hepatitis belongs to the category of "liver disease" in traditional Chinese medicine. Liver disease is mostly caused by feeling the poison of dampness and turbidity during epidemics; or improper diet, which damages the spleen and stomach, resulting in abnormal movement and transformation of water and grain qi, internal resistance of dampness and turbidity, stagnant steaming...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P1/16
Inventor 孙泰俊邵成雷刘玉芹李丽张本永
Owner JINHE TIBETAN MEDICINE
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