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Chinese medicine combination for preventing and curing lung injury and pulmonary fibrosis and preparation method thereof

A technology for pulmonary fibrosis and a composition is applied in the field of traditional Chinese medicine compositions for preventing and treating lung injury and pulmonary fibrosis and the field of preparation thereof, which can solve the problems of lack of exact and effective treatment methods and drugs for lung injury and pulmonary fibrosis, and achieve no Adverse reactions, anti-pulmonary fibrosis, no toxic side effects

Inactive Publication Date: 2012-08-01
NO 1 THE PEOPLES HOSPITAL HUAIAN CITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no definite and effective treatment method and drug for the treatment of lung injury and pulmonary fibrosis

Method used

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  • Chinese medicine combination for preventing and curing lung injury and pulmonary fibrosis and preparation method thereof
  • Chinese medicine combination for preventing and curing lung injury and pulmonary fibrosis and preparation method thereof
  • Chinese medicine combination for preventing and curing lung injury and pulmonary fibrosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Embodiment 1: prepare oral liquid according to the following method: get Platycodon grandiflorum, Fritillaria 28.6g each, honeysuckle, Dan cortex each 21.4g, mix and pulverize 100% and cross 100 mesh sieves, add 1000ml of water in the mixing powder placement container, after boiling Continue to simmer for 45 minutes, precipitate, filter, take the filtrate, concentrate in vacuo to 100ml, fill in separate bottles, 100ml per bottle, sterilize and seal.

Embodiment 2

[0018] Embodiment 2: Capsule making according to the following method: get Platycodon grandiflorum, Fritillaria 28.6g each, honeysuckle, Dan cortex 21.4g, mix and pulverize 100% and pass through a 100 mesh sieve, decoct 3 / 4 heavy medicine for 45 minutes, precipitate, Filtrate, take the filtrate, vacuum concentrate to 100ml; 1 / 4 of the weight is crushed again through a 200-mesh sieve, mixed evenly with the above liquid medicine, vacuum-dried or low-temperature oven-dried, sterilized, crushed, packed into capsules, 0.25g per capsule .

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Abstract

The invention discloses Chinese medicine combination for preventing and curing lung injury and pulmonary fibrosis and a preparation method thereof. The Chinese medicine combination comprises the following components in percentage by weight: 28.6 percent of balloonflower root, 28.6 percent of Zhejiang fritillary bulb, 21.4 percent of flos lonicerae, and 21.4 percent of moutan bark; the method for preparing oral liquid comprises the following steps: weighing all the components in percentage by weight, mixing and smashing the components through a 100-mesh sieve, adding mixed powder into a container, adding 500 ml of water into the container, boiling the water and then keeping boiling for 45 minutes, precipitating, filtering, fetching filtrate to be conducted to vacuum concentration to 100 ml, filling concentrated solution into bottles, ensuring that each bottle is 100 milliliters, and then performing sterilizing sealing; the method for preparing capsules comprises the following steps: weighing all the components in percentage by weight, mixing and smashing the components through a 100-mesh sieve, boiling 3 / 4 of the medicine for 45 mutinies, precipitating, filtering, fetching filtrate to be conducted to vacuum concentration to 100 ml, smashing 1 / 4 of the medicine again through a 200-mesh sieve to be uniformly mixed with the liquid medicine, performing vacuum drying or low-temperature drying, sterilizing, encapsulating, and ensuring that each capsule is 0.25 g. The Chinese medicine combination ensures that lung is prevented from chemotherapeutics injury and radiation injury, is resistant to pulmonary fibrosis, and does not have toxic side effect and untoward effect.

Description

technical field [0001] The invention relates to traditional Chinese medicine, in particular to a traditional Chinese medicine composition for preventing and treating lung injury and pulmonary fibrosis and a preparation method thereof. Background technique [0002] As we all know, lung injury caused by chemotherapy drugs and radiation therapy often manifests as alveolitis in the early stage, and a large number of inflammatory cells infiltrate in the alveoli. Then, with the participation of inflammatory cells, various cytokines and inflammatory mediators are released in large quantities, which expands tissue damage. Cause pulmonary interstitial hyperplasia, leading to pulmonary fibrosis. Since the mechanism of pulmonary fibrosis after lung injury is not completely clear, once it develops into pulmonary fibrosis, it is often irreversible and seriously threatens the lives of patients. Therefore, how to prevent and treat lung injury caused by chemotherapy drugs and radiation the...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61K9/08A61K9/48A61P11/00
Inventor 郭海龚婕宁刘宝瑞陈小飞何敬东董丽霞陈艳
Owner NO 1 THE PEOPLES HOSPITAL HUAIAN CITY
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