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Composition with good curative effect by aiming at various osteoarthritis symptoms

A composition and chondroitin sulfate technology are applied in the directions of medical preparations containing active ingredients, drug combinations, sulfur/selenium/tellurium active ingredients, etc., and can solve problems such as strong side effects

Inactive Publication Date: 2012-08-15
SHANGHAI INNOSTAR BIO TECH +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Traditional drug treatment for osteoarthritis is non-steroidal anti-inflammatory drugs such as aspirin, acetaminophen, indomethacin, naproxen, naproxen, diclofenac, ibuprofen, nimesulide, Fecoxib, celecoxib etc., although this class medicine can alleviate the symptom of pain to a certain extent, but the side effect of this class medicine is very strong, as renal failure, peptic ulcer etc., therefore, urgently need to develop a A substance with good curative effect and few side effects to meet the needs of patients

Method used

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  • Composition with good curative effect by aiming at various osteoarthritis symptoms
  • Composition with good curative effect by aiming at various osteoarthritis symptoms
  • Composition with good curative effect by aiming at various osteoarthritis symptoms

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026]

[0027] Mix shark chondroitin sulfate, dimethyl sulfone, glucosamine hydrochloride, vitamin C, manganese sulfate, microcrystalline cellulose, and starch according to the above ratio, add an appropriate amount of 60% ethanol to make a soft material, and pass through a 24-mesh sieve Granulate, dry at 50°C for 2 hours, pass the dried granules through a 30-mesh sieve for granulation, add magnesium stearate, mix well, and compress into tablets.

Embodiment 2

[0029]

[0030] Mix shark chondroitin sulfate, dimethyl sulfone, glucosamine hydrochloride, vitamin C, manganese sulfate, microcrystalline cellulose, and starch according to the above ratio, add an appropriate amount of 60% ethanol to make a soft material, and pass through a 24-mesh sieve Granulate, dry at 50°C for 2 hours, pass the dried granules through a 30-mesh sieve for granulation, add magnesium stearate, mix well, and pack into hard capsules.

Embodiment 3

[0032]

[0033]

[0034] Mix shark chondroitin sulfate, dimethyl sulfone, glucosamine hydrochloride, vitamin C, manganese sulfate, microcrystalline cellulose, and starch according to the above ratio, add an appropriate amount of 60% ethanol to make a soft material, and pass through a 24-mesh sieve Granulate, dry at 50°C for 2 hours, pass the dried granules through a 30-mesh sieve for granulation, add magnesium stearate, mix well, and compress into tablets.

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PUM

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Abstract

The invention relates to a composition with a good curative effect by aiming at various osteoarthritis symptoms, and is characterized in that the composition contains 1-50 parts of shark chondroitin sulfate, 1-50 parts of dimethyl sulfone, 1-50 parts of glucosamine hydrochloride, 1-10 parts of vitamin C, 1-10 parts of sodium molybdate and 1-10 parts of manganese sulfate, and other nutrition components, such as Beta- sitosterol, vitamin K, vitamin E, immunoglobulin, vitamin D and the like can be added. The composition disclosed by the invention can be prepared into various oral dosages by pharmaceutically acceptable carriers and additives, and the composition has good treating effect on various bone and arthrosis pain / chronic pain diseases.

Description

technical field [0001] The invention relates to a composition and its application in the preparation of various medicines and (health care) foods for preventing and treating various osteoarthritis and other related symptoms. Background technique [0002] Many people think that osteoarthritis is a disease of the elderly. In fact, the incidence rate of osteoarthritis is gradually becoming younger. Compared with the elderly, young patients are relatively less. According to relevant statistics, about 65%-75% of the elderly over 50 years old have different degrees of osteoarthritis. suffering from osteoarthritis disease. [0003] Modern medicine believes that osteoarthritis is mainly related to the increasing age of the disease and endocrine disorders. It can also be caused by trauma and improper posture. Genetic factors also play a role in this disease. [0004] Clinical manifestations: Onset is slow, localized, and aggravated by frequent activities, which can be relieved by r...

Claims

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Application Information

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IPC IPC(8): A61K33/32A61K39/395A23L1/29A61P19/02A61K31/10A61K31/122A61K31/355A61K31/375A61K31/575A61K31/59A61K31/7008A61K31/737A23L33/00
Inventor 黄丽芳张呈菊杨斌
Owner SHANGHAI INNOSTAR BIO TECH