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Multi-channel wireless cascade surface plasma resonance spectrometer

A surface plasmon and plasmon resonance technology, applied in instruments, scientific instruments, material analysis by optical means, etc., can solve problems such as the inability to meet the needs of high-throughput detection, reduce instrument costs, ensure instrument performance, and facilitate and flexible configuration Effect

Inactive Publication Date: 2012-08-22
王利兵
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The technical problem to be solved by the present invention is: to overcome the fact that the existing SPR instruments mainly adopt single-channel or dual-channel detection mode, which cannot meet the requirements of high-throughput detection, and propose a multi-channel wireless cascaded surface plasmon resonance spectrometer

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  • Multi-channel wireless cascade surface plasma resonance spectrometer
  • Multi-channel wireless cascade surface plasma resonance spectrometer
  • Multi-channel wireless cascade surface plasma resonance spectrometer

Examples

Experimental program
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Effect test

Embodiment 1

[0019] See attached figure 1 As shown, a multi-channel wireless cascaded surface plasmon resonance spectrometer is composed of several independent 8-channel surface plasmon resonance spectrum wireless detection modules 1 (8-channel-SPR), and a main control computer 2, using Wi-Fi (IEEE 802.11) wireless communication method for two-way data transmission. Among them, the 8-channel-SPR wireless detection module 1 is responsible for the high-throughput detection of multi-channel samples, and sends the detection data to the main control computer through the wireless network in real time, and at the same time accepts the control instructions of the main control computer; the main control computer 2 is used for Wireless data reception, data processing and centralized control. According to specific application needs, 1~12 8-channel-SPR wireless detection modules can be configured arbitrarily, and the main control computer can automatically identify 8-channel-SPR modules in the area, ...

Embodiment 2

[0021] see figure 2 As shown, the 8-channel surface plasmon resonance spectrum wireless detection module is composed of 8 independent detection channels. Except that the automatic control system 11, the wireless transmission module 12 and the time-division multiplexing optical fiber detection system 15 are shared by 8 channels, other micro The flow control system 14 and the SPR sensing system 13 are independent sets for each channel. The core of the microfluidic system 14 is the microfluidic sample cell, which is responsible for the delivery of the mixed solution of the sample and the mobile phase, and precisely controls the flow rate and stability of the fluid in the sample cell. The SPR sensing system 13 detects and analyzes the samples in the sample pool, adopts the wavelength modulation method, and selects the prism sensing component 131 or the fiber optic sensing component 132 according to the specific application requirements, breaking the prism sensing unit or the fibe...

Embodiment 3

[0023] see image 3 As shown, the single-channel SPR sensing detection system includes a prism sensing component 131, an optical fiber sensing component 132 and a time-division multiplexing optical fiber detection system 15, etc., wherein the prism sensing component 131 and the optical fiber sensing component 132 are based on user needs Choose one. The prism sensing component light source 1311 and 1321. The optical fiber sensing component light source 1321 uses a halogen tungsten light source; the prism sensing component 131 adopts a cylindrical prism 1315, and its cross section is an isosceles triangle, and the bottom surface is coated with a flat metal reflective film 1316, the waist The incident high-reflection film and the exit high-reflection film are respectively coated on the surface, and the outgoing light of the prism is coupled into the optical fiber 1318 after being focused by the lens 1317, and then enters the time-division multiplexing optical fiber detection syst...

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Abstract

The invention relates to a multi-channel wireless cascade surface plasma resonance spectrometer which is characterized by comprising a plurality of independent 8-channel surface plasma resonance spectrum wireless detection modules (8-channel-SPR (Surface Plasmon Resonance)) and a main control computer for wireless data receiving and data processing and controlling. The number of the 8-channel-SPR modules can be optionally configured to be 1-12; the main control computer can automatically identify the 8-channel-SPR modules in an area; and the surface plasma resonance spectrometer with 96 channels at most can be formed, so that the high-throughput analysis of 96 samples is realized. The multi-channel wireless cascade surface plasma resonance spectrometer has the advantages that the spectrometer adopts a framework structure collected in a distributive manner and managed in a centralizing manner, the space limit is broken through in a wireless cascade manner, the configuration is convenient and flexible, and different scales of application can be satisfied. Meanwhile, each independent 8-channel-SRP module comprises a micro-flow control system, a SPR sensing system, a time division multiplexing optical fiber light spectrum detection system, an automatic control system and a wireless transmission module, and the detection of the massive samples can be quickly finished. The multi-channel wireless cascade surface plasma resonance spectrometer has the characteristics of super sensitivity, high flux, low cost and the like.

Description

technical field [0001] The invention relates to a high-flux, high-sensitivity hazard factor analysis and measurement equipment, in particular to a multi-channel wireless cascaded surface plasmon resonance spectrometer. Background technique [0002] Surface Plasmon Resonance (SPR), also known as molecular interaction spectrometer, as an ultra-sensitive and rapid detection technology, is widely used in the study of molecular interactions in the fields of life sciences, drug screening, food safety, etc. a great application prospect. The SPR detection process does not need to label samples, maintains molecular activity, and the detection process is convenient and fast, with the characteristics of high sensitivity and high precision. It is generally favored by large foreign instrument companies and has begun large-scale research and development. [0003] Existing SPR instruments mainly use single-channel or dual-channel detection modes, which cannot meet the needs of high-throug...

Claims

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Application Information

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IPC IPC(8): G01N21/55G01N21/552
Inventor 王利兵周鹏苏荣欣
Owner 王利兵
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