Child cefalexin composition

A technology of ampicillin composition and cephalosporin, which is applied in the directions of inactive components of polymer compounds, pill delivery, antibacterial drugs, etc., can solve the problems of low bioavailability, difficult swallowing by patients, inconvenient taking, etc., and achieves high safety. , Shorten freeze-drying time, no gritty effect
CN102648899AActive Publication Date: 2012-08-29HAINAN WEI KANG PHARMA QIANSHAN
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HAINAN WEI KANG PHARMA QIANSHAN
Publication Date
2012-08-29

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Abstract

The invention discloses a child cefalexin composition, which relates to the technical field of medicinal preparations. A prescription of the composition consists of the following components in percentage by weight: 25 percent of cephalexin, 25-75 percent of mannitol, 2-4 percent of gelatin and 0.1-0.15 percent of sucralose. The invention further provides a child cefalexin composition freeze-driven oral disintegrated tablet containing the child cefalexin composition. The freeze-driven oral disintegrated tablet has the advantages of simple composition, no need of water for taking, no need of chewing, disintegration time of not more than 2 seconds in the oral cavity of a human being, quick response, small residues in intestinal canals, full absorption, small side effects, good mouthfeel and particular suitability for infant patients.
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Description

technical field

[0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a pediatric cephalexin composition and a pediatric cephalexin composition freeze-dried orally disintegrating tablet made from the composition and a preparation method thereof. Background technique

[0002] Cephalexin is suitable for most strains of Streptococcus pneumoniae, Streptococcus hemolyticus, Staphylococcus penicillinase-producing or non-producing, and most strains are sensitive to this product. This product has good antibacterial effect on Neisseria, but Haemophilus influenzae is less sensitive to this product; this product has certain antibacterial effect on some Escherichia coli, Proteus mirabilis, Salmonella and Shigella. The remaining Enterobacteriaceae, Acinetobacter, Pseudomonas aeruginosa, and Bacteroides fragilis all showed resistance to this product. Fusobacterium and Veillonella are generally sensitive to this product, and anaerobic Gram-po...

Claims

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