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Use of traditional Chinese medicine composition in preparation of drug for preventing and treating delayed encephalopathy after acute carbon monoxide poisoning

A technology of composition and traditional Chinese medicine, applied in the directions of drug combination, active ingredient of hydroxyl compound, pharmaceutical formula, etc., can solve the problems of slow recovery of brain tissue, accelerated carboxyhemoglobin, etc.

Active Publication Date: 2012-10-24
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hyperbaric oxygen can accelerate the decomposition of carboxyhemoglobin, promote the removal of carbon monoxide, and restore the oxygen-carrying function of hemoglobin; during hyperbaric oxygen therapy, the dissolved oxygen in plasma increases greatly, and the partial pressure of blood oxygen increases, which can quickly correct tissue hypoxia and improve cerebral insufficiency. Oxygen can promote the recovery of central nervous system function, but this recovery effect on brain tissue is very slow

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] a) The raw material drug formula is:

[0063] Ginseng 39.6g Leech 72.6g Wood Beetle 46.2g Frankincense 13.2g

[0064] Radix Paeoniae Rubra 33g Dalbergia 13.2g Sandalwood 13.2g Scorpio 19.8g Cicada slough 46.2g Centipede 6.6g Borneol 33g Fried Suanzaoren 33g;

[0065] b) Crushing process of medicinal materials:

[0066] The scorpion, leech, centipede, ground beetle and cicada slough five kinds of insect medicines, which are cleaned, washed and processed, are formulated according to the prescription and crushed by a pulverizer. The fineness of the powder reaches more than 80 mesh; The powdered medicinal powder is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the medicinal powder is less than 30-40 μm;

[0067] c) Extraction concentration and drying process:

[0068] Add water to extract the volatile oil of Jiangxiang and sandalwood, and then extract with water. Add appropriate amount of water to decoct the re...

Embodiment 2

[0073] a) The raw material drug formula is:

[0074] Ginseng 66g Leech 52.8g Wood Beetle 46.2g Frankincense 13.2g

[0075] Radix Paeoniae Alba 33g Dalbergia 13.2g Sandalwood 13.2g Scorpio 59.4g

[0076] Cicada slough 46.2g centipede 6.6g borneol 33g fried jujube kernel 33g

[0077] b) Crushing process of medicinal materials:

[0078] The scorpion, leech, centipede, ground beetle and cicada slough five kinds of insect medicines, which are cleaned, washed and processed, are formulated according to the prescription and crushed by a pulverizer. The fineness of the powder reaches more than 80 mesh; The powdered medicinal powder is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the medicinal powder is less than 70-90 μm;

[0079] c) Extraction concentration and drying process:

[0080] Add water to extract the volatile oil of Jiangxiang and sandalwood, and then extract with water. Add appropriate amount of water to deco...

Embodiment 3

[0084] Embodiment 3: the preparation of pill

[0085] a) The raw material drug formula is:

[0086] Ginseng 39.6g Leech 66g Wood Beetle 46.2g Frankincense 13.2g

[0087] Radix Paeoniae Alba 33g Dalbergia 13.2g Sandalwood 13.2g Scorpio 46.2g

[0088] Cicada slough 46.2g centipede 6.6g borneol 33g fried jujube kernel 33g

[0089] b) Crushing process of medicinal materials:

[0090] The scorpion, leech, centipede, ground beetle and cicada slough five kinds of insect medicines, which are cleaned, washed and processed, are formulated according to the prescription and crushed by a pulverizer. The fineness of the powder reaches more than 80 mesh; The powder after powder is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the powder is 10-20 μm; the medicinal materials to be pulverized are washed, dried and sterilized, and the ingredients are prepared;

[0091] c) Extraction concentration and drying process:

[0092] Add...

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Abstract

The invention discloses a use of a traditional Chinese medicine composition in preparation of a drug for preventing and treating delayed encephalopathy after acute carbon monoxide poisoning. The traditional Chinese medicine composition comprises ginseng, leech, centipede, scorpion, ground beeltle, periostracum cicada, red peony root and borneol. The traditional Chinese medicine composition has effects of supplementing qi and activating blood circulation, and dispersing blood stasis and dredging collateral. A clinical research shows that the traditional Chinese medicine composition has clear effects of preventing and treating delayed encephalopathy after acute carbon monoxide poisoning.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition. Specifically, the invention relates to the application of a traditional Chinese medicine composition in the preparation of medicines for preventing and treating delayed encephalopathy caused by carbon monoxide poisoning, which belongs to the field of traditional Chinese medicine applications. Background technique [0002] Delayed encephalopathy after acute carbon monoxide poisoning (delayed encephalopathy after acute carbon monoxide poisoning,) refers to the "false recovery period" in which patients with acute carbon monoxide (CO) poisoning recover after acute poisoning symptoms and appear normal or close to normal after several days or weeks. "After that, a group of neuropsychiatric symptoms, mainly acute dementia, reappeared. It usually occurs within two months after acute poisoning, and the morbidity and mortality rates are relatively high. There is still a lac...

Claims

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Application Information

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IPC IPC(8): A61K36/725A61P25/00A61K31/045A61K35/62A61K35/64A61K35/646A61K35/648
Inventor 肖维刚张秋艳吴中秋
Owner HEBEI YILING MEDICINE INST
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