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Anti-black eye lipid nanoparticle emulsion and preparation method thereof

A technology of lipid nanoparticles and dark circles, which is applied in the field of lipid nanoparticles, can solve the problems of inconvenient direct addition and use, and the difficulty of effective ingredients entering the deep layer of the skin, so as to improve the effect of anti-dark circles, and the effect of anti-dark circles is remarkable, The effect of small particle size

Active Publication Date: 2012-11-14
PROYA COSMETICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the solubility of frankincense resin extract, horse chestnut seed extract and tetrahydropiperine in water is less than 0.1%, and it is inconvenient to directly add and use in cosmetics
Moreover, the average particle size of traditional cosmetic creams and emulsions is greater than 200nm, and it is difficult for active ingredients to penetrate deep into the skin

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A preparation method for anti-dark circle lipid nanoparticle emulsion, adopts the following steps:

[0034] A. Weigh 12g of monoglyceride stearate (GLYCERYL STEARATE), 3.2g of hydrogenated soybean oil (HYDROGENATED SOYBEAN OIL), 6.3g of lecithin (LECITHIN), 3.1g of polyglyceryl-4 pentastearate (POLYGLYCERYL-4 PENTASTEARATE), heated to 85°C, mixed with a propeller agitator at 600 rpm for 10 minutes to obtain a uniform liquid oil phase;

[0035] B. Weigh 3.6g of frankincense resin extract, 1.5g of Aesculus aesculus seed extract, 0.3g of tetrahydropiperine, add it to the liquid oil phase obtained in step A, keep at 85°C, and use a propeller stirrer at 600 Stir at a speed of rpm for 10 minutes to disperse the mixture evenly in the liquid oil phase;

[0036] C. Weigh 68.7g of distilled water and heat to 85°C;

[0037] D. Mix the above oil phase and water phase, use a propeller agitator at 600 rpm, mix for 10 minutes, pour into a high-pressure homogenizer for emulsification...

Embodiment 2

[0046] A preparation method for anti-dark circle lipid nanoparticle emulsion, adopts the following steps:

[0047] A. Weigh 15g of monoglyceride stearate (GLYCERYL STEARATE), 2.6g of hydrogenated soybean oil (HYDROGENATED SOYBEAN OIL), 1.0g of hydrogenated wheat germ oil (HYDROGENATED WHEAT GERM OIL), 1.0g of white pond flower seed oil (LIMNANTHES ALBA ( MEADOWFOAM) SEED OIL), 8.3g lecithin (LECITHIN), 1.3g sorbitan sesquioleate (SORBITANSESQUIOLEATE), 0.9g polyglyceryl-4 stearate (POLYGLYCERYL-4STEARATE), 0.9g steareth -2 (STEARETH-2), 0.4g ceteareth-100 (CETEARETH-100), heated to 70°C, mixed with a propeller agitator at 600 rpm for 10 minutes to obtain a uniform liquid oil phase;

[0048] B. Weigh 2.2g frankincense resin extract, 1.3g horse chestnut seed extract, 0.1g tetrahydropiperine, add it to the liquid oil phase obtained in step A, keep at 70°C, and use a propeller stirrer at 600 Stir at a speed of rpm for 10 minutes to disperse the mixture evenly in the liquid oil ph...

Embodiment 3

[0059] A preparation method for anti-dark circle lipid nanoparticle emulsion, adopts the following steps:

[0060] A. Weigh 12g of monoglyceride stearate (GLYCERYL STEARATE), 4.8g of hydrogenated sweet almond oil (HYDROGENATED SWEET ALMOND OIL), 7.8g of lecithin (LECITHIN), 3.8g of sucrose stearate (SUCROSE STEARATE), heat To 78°C, use a propeller agitator at 600 rpm, and mix for 10 minutes to obtain a uniform liquid oil phase;

[0061] B. Weigh 1.1g of Boswellia resin extract, 0.4g of Aesculus aesculus seed extract, 0.1g of tetrahydropiperine, add it to the liquid oil phase obtained in step A, keep at 78°C, and use a propeller stirrer at 600 Stir at a speed of rpm for 10 minutes to disperse the mixture evenly in the liquid oil phase;

[0062] C. Weigh 69.994g of distilled water and heat to 83°C;

[0063] D. Mix the above oil phase and water phase, use a propeller agitator at 600 rpm, mix for 10 minutes, pour into a high-pressure homogenizer for emulsification, 70MPa, and ho...

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Abstract

The invention relates to an anti-black eye lipid nanoparticle emulsion which is characterized by comprising the following components: 0.5-7.3% of mixture of olibanum resin extract, European horse-chestnut seed extract and tetrahydropiperine, 1.0-19.6% of glycerol monostearate or vegetable fat or mixture of glycerol monostearate and vegetable fat, 0.5-11.8% of emulsifier, 0.006-1.3% of preservative and the balance of water, wherein the percent is mass percent. The method provided by the invention has the following advantages: the contents of the olibanum resin extract, the European horse-chestnut seed extract and the tetrahydropiperine are high, and the emulsion has good stability and obvious anti-black eye efficacy and is convenient to be blended in a cosmetic formula in a cooling mode.

Description

technical field [0001] The invention relates to the technical field of lipid nanoparticles, in particular to an anti-dark circle lipid nano-particle emulsion, and simultaneously the invention also relates to a preparation method of the anti-dark circle lipid nano-particle emulsion. Background technique [0002] The skin of the eyelids is the thinnest and most delicate in the human body. Dark circles under the eyes greatly reduce the beauty and affect people's mental state. Dark circles under the eyes of young people are usually due to excessive fatigue, which causes the blood circulation rate of capillaries under the eyelids to be too slow, the oxygen content in the blood decreases, the permeability of capillaries increases, and local congestion occurs, resulting in dark circles . With the acceleration of the pace of life and the increasing pressure of life, it is common to stay up late. Therefore, skin care products for dark circle repair are favored by more and more beaut...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K8/92A61K8/49A61K8/06A61Q19/00
Inventor 蒋丽刚陆海英刘丽
Owner PROYA COSMETICS
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