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Magnetic acoustic resonator sensor

A technology of sensors and resonators, applied in the field of sensing devices, can solve the problems of low sensitivity of acoustic sensors and achieve the effect of easy detection

Active Publication Date: 2013-02-06
中科康磁医疗科技(苏州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In particular, the present invention attempts to solve the above-mentioned low sensitivity problem of existing acoustic wave sensors

Method used

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  • Magnetic acoustic resonator sensor
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  • Magnetic acoustic resonator sensor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] This paper describes a novel chemically activated mechanical switch based on a composite acoustic resonator.

[0061] The device diagram is shown in figure 1 middle. A planar helical coil was provided to electromagnetically excite the harmonics of a composite resonator made of a quartz disk and a pH-sensitive hydroxyethyl methacrylate-methacrylate copolymer based hydrogel acoustic thick-film coating. Coaxial connections are made between the helical coil and the signal generator, AM detector and lock-in amplifier. The detector uses a differential diode detection circuit to subtract the RF signal returned by the coil from the larger excitation signal generated by the signal generator. To report back the frequency, amplitude, and Q-factor of a composite resonant device, use LabView TM The software processes the raw amplitude and frequency data points collected from the spectrogram.

[0062] Measurements of acoustic resonance properties up to 100 MHz were performed with...

example

[0069] 2-Hydroxyethyl methacrylate (HEMA, 97%), ethylene glycol dimethacrylate (EDMA, also known as ethylene glycol dimethacrylate), methacrylic acid (MAA), dimethyl Oxyphenylacetophenone (DMAP), 2-propanol and (methacryloylpropyl)triethoxysilane were supplied by Aldrich Chemical Co. (Gillingham, UK). All other chemicals were of analytical grade and supplied by Sigma or Aldrich. Aluminized 100 μm thick polyester film (MET401 grade) was purchased from HiFi Industrial Film Ltd. (Stevenage, UK).

[0070] Composite resonator fabrication

[0071] A monomer mixture was prepared from HEMA (89 mole %), EDMA (crosslinker, 5 mole %), MAA (6 mole %), and an equal volume of 2-propanol. The photoinitiator dimethoxyphenylacetophenone (DMAP) was then added to a final concentration of 1% (w / v). The crystals were treated overnight with a 1% (w / v) solution of trimethoxysilylpropyl methacrylate in acetone. Place an aluminized polyester sheet on a flat glass plate and pipette approximately 5 ...

Embodiment 2

[0105] A glucose sensor capable of remotely monitoring glucose concentration is described below.

[0106] Synthesis of glucose-sensitive copolymers of 3-acrylamidophenylboronic acid (3-APB) and acrylamide by UV-initiated radical polymerization using N,N-methylenebisacrylamide (MBA) as a crosslinker at room temperature . pK of poly(acrylamide-co-3-APB) a is about 8.6, but the pK of the complex after glucose binding a The value decreases, so the copolymer can measure the glucose concentration at physiological pH.

[0107] The main approach described here is to incorporate a glucose-responsive poly(acrylamide-co-3-APB) membrane into a magnetoacoustic resonant sensor (MARS) and study the response of the sensing device to changes in the concentration of glucose in solution.

[0108] Complexation of boric acid and cis-diol

[0109] The reversible binding between boronic acid and cis-diol is shown in Figure 7In , the binding is pH dependent. The chemical structure of poly(acry...

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Abstract

The present invention relates to a sensing apparatus comprising a resonator, a sensor and a detector, wherein the sensor is mechanically coupled to the resonator, the sensor comprises a sensor material which changes between a first state and a second state when exposed to a change in the surrounding environment, wherein the sensor is driven by the resonator and the detector is responsive to the change in state of the sensor material, wherein the sensor material is in the form of an acoustically thick layer.

Description

technical field [0001] The present invention relates to sensing devices, preferably chemically activated electromechanical sensing devices employing hydrogels. Background technique [0002] Hydrogels capable of changing shape or volume when exposed to different chemical environments have been used as pH sensors, ion sensors, chemical sensors, gas sensors, and temperature sensors, and as mechanical actuation elements. See for example: Bashir, R. et al., Micromechanical cantilever as an ultrasensitive pH microsensor, AppliedPhysics Letters, 2002, 81(16): 3091-3093 pages; Zhang, L. and W.R.Seitz, A pH sensorbased on force generated by pH- Dependent polymer swelling, Analytical and Bioanalytical Chemistry, 2002, 373(7): 555-559 pages; van der Linden, H. et al., Development of stimulus-sensitive hydrogels suitable for actuators and sensors in microanalytical devices. Sensors and Materials, 2002, 14 (3): 129 pages to 139 pages; Mayes, A.G., etc., Metal ion-sensitive holographic s...

Claims

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Application Information

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IPC IPC(8): G01N29/02G01N29/036
CPCG01N2291/02818G01N2291/024G01N29/036G01N2291/025G01N29/022
Inventor C·洛维A·史蒂文森B·阿莱雅雷斯特贝尔
Owner 中科康磁医疗科技(苏州)有限公司