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Avian colibacillosis treatment traditional Chinese medicine and preparation method thereof

A technology for chicken colibacillosis and traditional Chinese medicine granules, which can be used in pharmaceutical formulations, antibacterial drugs, medical preparations containing active ingredients, etc. , to achieve the effect of not easy to absorb moisture and agglomerate, good therapeutic effect, and low drug cost.

Active Publication Date: 2014-11-19
QINGDAO VLAND BIOTECH INC +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The repeated outbreaks of Escherichia coli and the poor control effect have greatly restricted the healthy development of the chicken industry and caused serious food safety problems

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The raw material prescription is: gypsum 60g; honeysuckle 15g; scrophulariaceae 12g; scutellaria baicalensis 10g; rehmannia 10g; forsythia 8g; gardenia 8g; And the right amount of dextrin.

[0032] Preparation of granules: crush honeysuckle, scrophulariaceae, and forsythia through an 80-mesh sieve, add 0.4g of cellulase, add 70ml of water, mix well, treat at 50°C for 15 hours, add ethanol to make the alcohol content reach 50% , heated to reflux for 1 hour, filtered, and concentrated under reduced pressure to obtain concentrated solution A; crush gypsum, scutellaria baicalensis, rehmannia root, gardenia jasmine, gentian, candiding, isatidis, Anemarrhena anemarrhena, and Ophiopogon japonicus through an 80-mesh sieve, and add 1.3g cellulose enzyme, add water 8 times the weight of medicinal material, mix well, treat at 50°C for 15 hours, heat and extract for 1 hour, filter to obtain extract B; mix concentrated solution A and extract B, concentrate under reduced pressure to ...

Embodiment 2

[0035] The raw material prescription is: gypsum 50g; honeysuckle 10g; scrophulariaceae 10g; skullcap 8g; rehmannia 8g; forsythia 10g; gardenia 10g; And the right amount of soluble starch.

[0036]Preparation of granules: crush honeysuckle, scrophulariaceae, and forsythia through a 65-mesh sieve, add 0.5g of cellulase, add 70ml of water, mix well, treat at 45°C for 20 hours, add ethanol to make the alcohol content reach 50% , heated to reflux for 1 hour, filtered, and concentrated under reduced pressure to obtain concentrated solution A; crush gypsum, scutellaria baicalensis, rehmannia root, gardenia jasmine, gentian, candiding, isatidis, Anemarrhena anemarrhena, and Ophiopogon japonicus through a 65-mesh sieve, and add 1.5g cellulose enzyme, add water 6 times the weight of medicinal materials, mix well, treat at 45°C for 20 hours, heat and extract for 1 hour, filter to obtain extract B; mix concentrate A and extract B, concentrate under reduced pressure to relative density It...

Embodiment 3

[0039] The granule that embodiment 1 makes is to the therapeutic effect of chicken escherichia coli infection that causes pyrexia:

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Abstract

The present invention discloses traditional Chinese medicine granules for avian colibacillosis treatment, wherein raw materials comprise, by crude drug, 30-90 g of gypsum, 3-20 g of honeysuckle, 2-30 g of figwort root, 2-15 g of baikal skullcap root, 2-15 g of unprocessed rehmannia root, 2-15 g of weeping forsythia fruit, 2-15 g of cape jasmine, 2-15 g of Chinese gentian root, 2-30 g of manyflower gueldenstaedtid herb, 2-40 g of indigowoad root, 2-15 g of common anemarrhena, 2-15 g of creeping liriope, and a proper amount of an excipient. The preparation method for the cooling-relieving therapy granules comprises: (1) adopting enzyme extraction on the drugs in the formula to prepare extract powder, (2) adding the excipient and mixing, and (3) carrying out granulation, drying and sub-packaging to obtain the finished product. The granule agent has functions of heat clearing, detoxication, yin nourishing and dysentery treatment, and has characteristics of high active ingredient content, significant therapy effect, easy taking and no toxic and side-effect.

Description

technical field [0001] The invention belongs to the field of medicaments, and in particular relates to traditional Chinese medicine granules for treating chicken colibacillosis and a preparation method thereof. Background technique [0002] The heat toxicity caused by Escherichia coli in chickens is equivalent to certain types of chicken colibacillosis in veterinary epidemiology. For the convenience of description, it is hereinafter referred to as chicken colibacillosis. [0003] Chicken colibacillosis is caused by avian pathogenic Escherichia coli E. coli , APEC) caused by acute or chronic bacterial infectious diseases, is one of the main diseases affecting the development of chicken industry. Existing surveys and diagnoses have shown that colibacillosis ranks first among bacterial diseases, accounting for 33% of the total cases. The survey of some large chicken farms in Beijing by Liu Guibin and others showed that chicken colibacillosis accounted for 0.94% of the total m...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61K9/16A61P31/04A61K33/06
CPCY02A50/30
Inventor 郝智慧王春元庞云露
Owner QINGDAO VLAND BIOTECH INC