Sterilization microcapsule suspending agent with adjustable releasing rate and preparation and usage method thereof
A technology of microcapsule suspension and controlled release, which is applied in the direction of microcapsule preparations, botany equipment and methods, fungicides, etc., can solve the problems of easy decomposition, achieve good slow-release performance, good permeability and quick-acting, Effect of good photolysis resistance
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Embodiment 1
[0052] Embodiment 1: LBL assembles NA microcapsules and performance testing
[0053] (1) LBL assembled NA microcapsules
[0054] 1) Disperse natamycin in deionized water to prepare a suspension, and ultrasonically refine the suspension for 5-10 minutes to obtain a uniform aqueous suspension A of 30 g / L natamycin;
[0055] 2) Assemble the first layer: add sodium alginate solution, Tween-80, sodium chloride and deionized water to the suspension A obtained in step 1) under stirring, so that the content of natamycin in the reaction system is 15g / L, the content of sodium alginate is 1g / L, the content of Tween-80 is 10g / L, and the content of sodium chloride is 14.6g / L. Immediately after the addition, adjust the pH of the system to 4.5. After reacting for 15-20min, centrifuge and water Wash 3 times, and finally resuspend the precipitate in deionized water to obtain a uniform aqueous suspension A1 of natamycin microcapsules with a natamycin content of 30 g / L;
[0056] 3) Assemble the...
Embodiment 2
[0096] The preparation of embodiment 2 microcapsule suspension
[0097] The microcapsule suspension prepared in Example 1 was left to stand and discarded different amounts of supernatant to obtain NA content respectively as microcapsule suspensions of 20g / L and 60g / L, and then press the components of Table 8-9 Each component is weighed according to the mass ratio to prepare a microcapsule suspension. The method is to weigh the anti-sedimentation agent first, add an appropriate amount of water to fully dissolve it, and make it into a paste, then add the weighed microcapsule suspension, and then add other ingredients, fully stir evenly under the condition of the mixer speed of 800-1000rpm, Natamycin microcapsule suspension (NACS). Microcapsule suspensions with 4-layer assembly and 8-layer assembly were prepared respectively, code-named NACS-4 and NACS-8, respectively.
[0098] Table 8 The mass ratio of each component of natamycin microcapsule suspension (NACS-4) (1)
[0099] ...
Embodiment 3
[0102] Embodiment 3 Microcapsule drug effect test
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