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Compound traditional Chinese medicine superfine powder dispersion preparation and preparation method thereof

A compound traditional Chinese medicine and superfine powder technology, which is applied in food preparation, medical preparations containing active ingredients, drug combinations, etc., can solve the problem of affecting the dissolution, release and absorption of medicinal substances, incomplete extraction of active ingredients, and damage to the cell structure of medicinal materials. To achieve the effect of improving bioavailability and curative effect, reducing drug dosage, and enhancing drug curative effect

Active Publication Date: 2013-03-13
LUNAN PHARMA GROUP CORPORATION
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these preparation methods are all made from decoction pieces through extraction and processing, and the preparation process will cause the loss of medicinal components and the waste of medicinal materials.
Conventional processing and extraction methods cannot effectively destroy the cell structure of medicinal materials, and the extraction of active ingredients is incomplete, which affects the dissolution, release and absorption of medicinal substances
Moreover, traditional Shengmai dosage forms have disadvantages such as low bioavailability, slow onset of action, small drug loading and inconvenient administration.

Method used

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  • Compound traditional Chinese medicine superfine powder dispersion preparation and preparation method thereof
  • Compound traditional Chinese medicine superfine powder dispersion preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1 The preparation of superfine powder Shengmai dispersion preparation

[0041] A medicinal material crushing process:

[0042] Clean 1 part by weight of ginseng and 2 parts by weight of Ophiopogon japonicus, dry them in the air, place them in an oven at 40°C-50°C and dry them with hot air for 1 hour, take them out, cut the ginseng into 3-5cm long sections, and set aside;

[0043] Grind the dried ginseng and Ophiopogon japonicus slices respectively to obtain coarse powder, which is passed through a 24-mesh sieve;

[0044] Ginseng, Ophiopogon japonicus coarse powder, 1 weight part of schisandra chinensis and 5% sucrose are subjected to cutting-type ultrafine grinding together, so that the average particle size of the medicinal powder is less than 28 μm, and the ambient temperature of the ultrafine grinding is -5 ° C to -10 ° C, and the three flavors are obtained. Mixed powder of medicinal materials and sucrose superfine powder;

[0045] B. Preparation proces...

Embodiment 2

[0047] Embodiment 2 The preparation of superfine powder Shengmai dispersion preparation

[0048] A medicinal material crushing process:

[0049] Clean 3 parts by weight of ginseng and 6 parts by weight of Ophiopogon japonicus, dry them in the air, place them in an oven at 40°C to 50°C and dry them with hot air for 1.5 hours, take them out, cut the ginseng into 3-5cm long sections, and set aside;

[0050] Grind the dried ginseng and Ophiopogon japonicus slices respectively to obtain coarse powder, which is passed through a 24-mesh sieve;

[0051] Ginseng, Ophiopogon japonicus coarse powder, 3 parts by weight of schisandra chinensis and 10% glucose are subjected to airflow ultrafine pulverization, so that the average particle size of the medicinal powder is less than 40 μm, and the ambient temperature of ultrafine pulverization is -5 ° C ~ -10 ° C, and the three medicinal materials are obtained. Mix powder with glucose superfine powder;

[0052] B. Preparation process:

[00...

Embodiment 3

[0054] Embodiment 3 The preparation of superfine powder Shengmai dispersion preparation

[0055] A medicinal material crushing process:

[0056] Clean 2 parts by weight of ginseng and 4 parts by weight of Ophiopogon japonicus, dry them in the air, place them in an oven at 40°C-50°C and dry them with hot air for 1.2 hours, take them out, cut the ginseng into 3-5cm long sections, and set aside;

[0057] Grind the dried ginseng and Ophiopogon japonicus slices respectively to obtain coarse powder, which is passed through a 24-mesh sieve;

[0058] Ginseng, Ophiopogon japonicus coarse powder, 2 parts by weight of schisandra chinensis and 8% sorbitol are subjected to impact ultrafine grinding together, so that the average particle size of the medicinal powder is less than 30 μm, and the ambient temperature of the ultrafine grinding is -5 ° C ~ -10 ° C, Obtain the mixed powder of three herbs and superfine powder of sorbitol;

[0059] B. Preparation process:

[0060] Add 22% cocoa ...

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Abstract

The invention discloses a compound traditional Chinese medicine superfine powder dispersion preparation and a preparation method thereof. The compound traditional Chinese medicine superfine powder dispersion preparation has the effects of supplementing Qi and nourishing Yin, and restoring pulse and promoting the secretion of saliva or body fluid. A superfine powdering technology is adopted to crush three vegetation medicinal materials, namely, ginseng, radix ophiopogonis and fructus schisandrae, in order to overcome the defects of a conventional crushing technology and a conventional preparation technology; and the industrialization of the crushing fineness superfine powdering technology for medicines of preparation and the superfine powdering technology of traditional Chinese medicines can be realized. According to the compound traditional Chinese medicine superfine powder dispersion preparation and the preparation method thereof, the superfine powder pulse activating dispersion preparation is directly used as medicine in form of superfine powder of traditional Chinese medicines, so that the loss of effective components can be avoided, the absorption of the medicine and the bioavailability can be improved, the effect is obviously improved, and the clinical effect is improved; and as the clinical effect inspection test shown, the superfine powder pulse activating dispersion preparation is superior to the pulse activating products processed by a general crushing technology and a traditional preparation technology.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine superfine powder dispersion preparation with the functions of nourishing qi and nourishing yin, restoring pulse and promoting body fluid and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Shengmaiyin is a famous traditional prescription derived from the ancient prescription Shengmaisan. It is a classic prescription for nourishing qi and nourishing yin. Shengmaisan was first published in "The Origin of Medicine" in 1186 and has a history of more than 800 years. Shengmai Yin is composed of three traditional Chinese medicines of ginseng, Ophiopogon japonicus and Schisandra chinensis. It has the functions of nourishing qi and promoting body fluid, astringing yin and stopping sweating, and it mainly treats the syndrome of deficiency of qi and yin. [0003] The treatment of this prescription is the evil of warm heat and summe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P1/14A23L1/29A23L33/00
Inventor 赵志全李守信李蔚群邱新建
Owner LUNAN PHARMA GROUP CORPORATION
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