The invention relates to the technical field of traditional chinese medicines, in particular to a traditional chinese medicine compound for relieving eczema, and a slow-release agent as well as a preparation method and application. The traditional chinese medicine compound is prepared from the following raw materials of scutellaria baicalensis, coptis chinensis, divaricate saposhnikovia root and atractylodes lancea. According to the traditional chinese medicine compound for relieving eczema, and the slow-release agent as well as a preparation method and application, after a traditional chinesemedicine is nanocrystallized, the bioavailability of the medicine can be improved, the onset time of the medicine is advanced, and the medicine effect of the original medicine is enhanced; a nano-scale molecular material is used as a carrier material to carry the medicine, so that the medicine is adsorbed or coated in the nano-carrier, the release time of the medicine can be delayed, and the medicine can be automatically released at a preset speed within preset time; and by increasing the dissolution rate of active ingredients of the traditional chinese medicine, the variety of pharmaceuticaldosage forms can be increased, and the development of multiple products such as gel paste, mist and emulsion is facilitated; and by using a proper gel carrier, the traditional chinese medicine compound can be promoted to permeate into corresponding epidermal cells to enter targets, the medicine effect for relieving eczema is improved, and the unstable medicine effect, caused by uneven dissolution, for relieving eczema is reduced.