The invention discloses a three-dimensional pawpaw and pineapple cultivation method which comprises the following steps: 1, selecting a winter-warming type greenhouse; 2, improving the soil and adjusting the acidity, namely, deeply turning over the soil for 0.6-0.8cm before the greenhouse is built, and when the soil is deeply turned over, spreading 25m<3>+/-5m<3> of cow dung per mu and meanwhile spreading 100kg+/-25kg of sulfur powder per mu; 3, planting time, namely, planting in spring when the indoor temperature is more than 15 DEG C, wherein vegetatively propagated pawpaw seedlings which are planted within a period from October to November last year; 4, managing after planting, namely, fertilizing, drying, watering, managing the tree bodies and preventing and preventing and controlling diseases and insect pests; and 5, harvesting and packaging fruits. The three-dimensional cultivation mode is adopted on the basis of the height difference of pawpaw and pineapple plants and the different requirements on illumination intensity, the utilization rate of the greenhouse and the land is improved, and the economic and social benefits are high.