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Bee venom composition with wrinkle removing effect

A composition and technology of bee venom, applied in skin care preparations, cosmetics, cosmetic preparations, etc., can solve problems such as potential safety hazards and insignificant anti-wrinkle effects, and achieve safety assurance, simplified bee venom purification process, and stable good sex effect

Active Publication Date: 2013-03-20
SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problems that the existing anti-wrinkle cosmetics have potential safety hazards, can only act on the surface layer of the skin, cannot penetrate deep into the dermis or even muscle tissue, and have insignificant anti-wrinkle effects, and provide a safer anti-wrinkle cosmetic that can act at the same time. A bee venom composition with anti-wrinkle effect for deep wrinkle removal in the epidermis, dermis and muscle tissue.

Method used

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  • Bee venom composition with wrinkle removing effect
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Use a bee venom collector to collect crude wasp venom, add 25 volumes of water to fully dissolve it, centrifuge at 8000 g for 15 minutes, ultrafilter the supernatant through an ultrafiltration membrane with a molecular weight cut-off of 10000 Da, and freeze-dry the filtrate to obtain bee venom.

[0037] The bee venom composition with anti-wrinkle effect of the present embodiment is composed of the following components based on the total mass percentage of 100%:

[0038] Phase A: carbomer 0.2%, glycerin 4%, propylene glycol 3%, deionized water balance.

[0039] Phase B: Cetearyl Ether-2 1.5%, Cetearyl Ether-21 2%, Jojoba Oil 3%, Cetearyl Alcohol 2%, Glyceryl Monostearate 1%, Caprylic Acid / Capric Triglyceride 4%, Ethylhexyl Palmitate 3%, Dimethicone 2%, Isopropyl Myristate 3%, Ethylparaben 0.1%.

[0040] Phase C: bee venom 0.1% (added in the form of a 50% bee venom solution pre-prepared with deionized water).

[0041] Phase D: Azone / PEG-40 hydrogenated castor oil 1%, t...

Embodiment 2

[0045] The crude bee venom was collected by a bee venom collector, fully dissolved by adding 10 times the volume of water, centrifuged at 5000g for 30min, the supernatant was ultrafiltered through an ultrafiltration membrane with a molecular weight cut-off of 10000Da, and the filtrate was freeze-dried to obtain bee venom.

[0046] The bee venom composition with anti-wrinkle effect of the present embodiment is composed of the following components based on the total mass percentage of 100%:

[0047] Phase A: carbomer 0.1%, glycerin 5%, propylene glycol 3%, deionized water balance.

[0048] Phase B: Ceteareth-2 1.2%, Ceteareth-21 1.5%, Hydrogenated Polyisobutylene 3%, Caprylic / Capric Triglyceride 3%, Ethylhexyl Palmitate 3% , Polydimethylsiloxane 2%, Ethylparaben 0.1%.

[0049] Phase C: Bee Venom 2% (added in powder form).

[0050] Phase D: Azone / PEG-40 hydrogenated castor oil 1%, triethanolamine 0.1%, phenoxyethanol / methylparaben / butylparaben / ethylparaben / propylparaben / isobuty...

Embodiment 3

[0054] Purchase wasp crude bee venom from Wuhan Yimin Bee Products Co., Ltd., add 30 times the volume of water to fully dissolve, centrifuge at 10,000 g for 10 minutes, and ultrafilter the supernatant through an ultrafiltration membrane with a molecular weight cut-off of 10,000 Da, then freeze-dry the filtrate to obtain bee venom .

[0055] The bee venom composition with anti-wrinkle effect of the present embodiment is composed of the following components based on the total mass percentage of 100%:

[0056] Phase A: xanthan gum 0.4%, acrylate / C 10-30 Alkyl acrylate crosspolymer 0.6%, EDTA-2Na 0.1%, glycerin 5%, propylene glycol 5%, butylene glycol 5%, deionized water balance.

[0057] Phase B: bee venom 0.00001% (add in the form of a 10% bee venom solution pre-prepared with distilled water), deionized water 20%.

[0058] Phase C: PEG-40 hydrogenated castor oil ester 1%, triethanolamine 0.2%, fragrance 0.1%, phenoxyethanol / methylparaben / butylparaben / ethylparaben / propylparaben...

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Abstract

The invention discloses a bee venom composition with a wrinkle removing effect. The composition comprises wrinkle removing cosmetic matrix components and bee venom. The bee venom is applied to wrinkle removing cosmetics for the first time, and can act on the epidermis, the dermis and the muscle tissues at the same time to realize deep wrinkle removal. By using good synergistic effect of the bee venom, hyaluronic acid and marine animal collagen peptide, the effects of moisturizing, improving dryness and laxity of skin, improving the elasticity of the skin, deeply removing wrinkles and the like are remarkably enhanced. The bee venom composition with the wrinkle removing effect is definite in effect component, stable in quality and diverse in variety, and can meet the requirements of different genders, ages and skin types.

Description

Technical field: [0001] The invention belongs to the field of cosmetics, in particular to a bee venom composition with anti-wrinkle effect. Background technique: [0002] Aging is an irresistible natural process of life, affected by many factors such as genetics, environment, social psychology, etc. Wrinkles are the external manifestations of body aging on the skin, which is related to skin relaxation, ultraviolet radiation, gravity, and repeated contraction of facial expression muscles. It is related to factors such as muscle tension itself. Generally speaking, the first wrinkles appear on the forehead and lower eyelids from the age of 25, fishtail-shaped fine wrinkles appear from the outer canthus at the age of 30, longitudinal wrinkles appear in front of the ears at the age of 35, and the wrinkles in front of the ears increase at the age of 40. Longitudinal wrinkles appear below the jaw. At the age of 45, the lower eyelid wrinkles are more obvious, and the red lips begi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/98A61K8/65A61K8/73A61Q19/08
CPCA61K8/987A61K8/65A61K8/735A61Q19/08A61K8/73A61K8/98
Inventor 陈华孙恢礼张偲潘剑宇蔡冰娜孙小钰
Owner SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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