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Phlomis maximowiczii extract, as well as extraction method and application thereof

A technology of Phalaenopsis grandiflora and its extraction method, which is applied in the field of medicine to achieve the effects of increasing SOD activity, simple and easy extraction method, and inhibiting lipid peroxidation

Inactive Publication Date: 2013-04-17
HENAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, except for Gu Haipeng et al.’s research on the fat-soluble components of Phyllostachys pratense, there are no other reports on the chemical constituents and pharmacological activities of Phyllostachys pratense

Method used

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  • Phlomis maximowiczii extract, as well as extraction method and application thereof
  • Phlomis maximowiczii extract, as well as extraction method and application thereof
  • Phlomis maximowiczii extract, as well as extraction method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] In this example, an extract of Phalaenopsis macrophyllum includes petroleum ether extract, ethyl acetate extract and n-butanol extract; the steps of the extraction method are as follows: (1) Take the whole Phalaenopsis macrophyllum herb, wash it, dry it in the shade, After crushing, soak and extract with methanol, recover methanol, and obtain the total extract for later use; (2) disperse the total extract in step (1) in ethanol aqueous solution, add petroleum ether for extraction, recover petroleum ether from the petroleum ether extract to obtain petroleum ether extract; (3) adding ethyl acetate to the solution after petroleum ether extraction in step (2) for extraction, and recovering ethyl acetate from the ethyl acetate extract to obtain ethyl acetate extract; (4) in step (3) Add n-butanol to the solution extracted with ethyl acetate, and recover n-butanol from the n-butanol extract to obtain n-butanol extract. The specific extraction steps are:

[0031] (1) Take 100...

Embodiment 2

[0036]In this example, an extract of Phalaenopsis macrophyllum includes petroleum ether extract, ethyl acetate extract and n-butanol extract; the steps of the extraction method are as follows: (1) Take the whole Phalaenopsis macrophyllum herb, wash it, dry it in the shade, After crushing, soak and extract with methanol, recover methanol, and obtain the total extract for later use; (2) disperse the total extract in step (1) in ethanol aqueous solution, add petroleum ether for extraction, recover petroleum ether from the petroleum ether extract to obtain petroleum ether extract; (3) adding ethyl acetate to the solution after petroleum ether extraction in step (2) for extraction, and recovering ethyl acetate from the ethyl acetate extract to obtain ethyl acetate extract; (4) in step (3) Add n-butanol to the solution extracted with ethyl acetate, and recover n-butanol from the n-butanol extract to obtain n-butanol extract. The specific extraction steps are:

[0037] (1) Take 1000...

Embodiment 3

[0042] In this example, an extract of Phalaenopsis macrophyllum includes petroleum ether extract, ethyl acetate extract and n-butanol extract; the steps of the extraction method are as follows: (1) Take the whole Phalaenopsis macrophyllum herb, wash it, dry it in the shade, After crushing, soak and extract with methanol, recover methanol, and obtain the total extract for later use; (2) disperse the total extract in step (1) in ethanol aqueous solution, add petroleum ether for extraction, recover petroleum ether from the petroleum ether extract to obtain petroleum ether extract; (3) adding ethyl acetate to the solution after petroleum ether extraction in step (2) for extraction, and recovering ethyl acetate from the ethyl acetate extract to obtain ethyl acetate extract; (4) in step (3) Add n-butanol to the solution extracted with ethyl acetate, and recover n-butanol from the n-butanol extract to obtain n-butanol extract. The specific extraction steps are:

[0043] (1) Take 100...

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Abstract

The invention discloses a Phlomis maximowiczii extract, as well as an extraction method and application thereof in preparation of antioxidant drugs and hepatoprotective drugs, and belongs to the technical field of medicines. The Phlomis maximowiczii extract contains a petroleum ether extract, an ethyl acetate extract and an n-butanol extract. The extraction method comprises the following steps: (1) collecting whole plants of Phlomis maximowiczii, washing, drying in a dark place, grinding and then extracting by soaking in methanol, recovering methanol to obtain a total extract; (2) dispersing the total extract in an ethanol aqueous solution, adding petroleum ether for extraction, and recovering petroleum ether to obtain the petroleum ether extract; (3) adding ethyl acetate into the solution for extraction after petroleum ether extraction, and recovering ethyl acetate to obtain the ethyl acetate extract; and (4) adding n-butanol into the solution after ethyl acetate extraction and recovering n-butanol to obtain the n-butanol extract. The Phlomis maximowiczii extract has antioxidant and hepatoprotective effects and can be used for preparing antioxidant and hepatoprotective health foods or drugs.

Description

technical field [0001] The invention relates to an extract, an extraction method, and an application in the preparation of antioxidant drugs and liver-protecting drugs, and belongs to the technical field of medicine. Background technique [0002] Hepatitis is one of the common liver diseases that seriously endanger human health. my country, as a high-incidence area of ​​liver disease, has more than 100 million people infected with hepatitis virus, but most of them have different degrees of liver damage. Some people are developing chronic hepatitis, It has become an arduous task to treat liver cirrhosis and liver cancer to block or delay their progression. At present, the general countermeasures for the treatment of liver diseases include protecting and improving liver function, reversing the changes of liver histology, blocking the development of chronic hepatitis to liver cirrhosis, and thus stopping the malignant evolution of the "trilogy of liver diseases". [0003] Acute...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61P1/16A61P39/06A23L1/29A23L33/00
Inventor 康文艺顾海鹏尹震花
Owner HENAN UNIVERSITY
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