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Transfusion bag with self-contraction function and transfusion bag special material thereof

A technology for infusion bags and special materials, which is applied in the field of infusion bags and special materials for infusion bags, which can solve the problems of high risk of leakage, achieve good toughening effect, reduce the risk of leakage, and improve the effect of dispersion

Active Publication Date: 2013-05-08
SICHUAN KELUN PHARMA RES INST CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the currently commercially available multi-layer co-extrusion film infusion bags also have their unavoidable shortcomings, that is, the periphery of the bag body needs to be welded and formed, and the risk of liquid leakage during transfer and transportation is relatively high

Method used

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  • Transfusion bag with self-contraction function and transfusion bag special material thereof
  • Transfusion bag with self-contraction function and transfusion bag special material thereof
  • Transfusion bag with self-contraction function and transfusion bag special material thereof

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0039] Experimental Example 1: Self-shrinkage effect detection of the present invention

[0040] The infusion bag of the present invention (prepared in Example 1), the polypropylene infusion bottle, and the three-layer co-extruded film infusion bag of the same specification are filled with sodium chloride injection (100ml, 0.9g) respectively, and 10 bags (bottles) are each taken Carry out the liquid discharge completeness test at a height of 1.2m from the ground. During the liquid discharge process, do not insert the vent needle or close the vent hole of the infusion set, and make the flow rate regulator of the infusion set fully open, and the infusion needle completely penetrates the combination. When the infusion is stopped, it is considered as the end point of the discharge. At this time, the infusion needle is pulled out and the sodium chloride injection remaining in the bag (bottle) is taken out and quantified with a syringe. The better the self-shrinking effect, the smal...

experiment example 2

[0043] Experimental example two, the present invention leaks bag rate detection after transportation test:

[0044] The infusion bag of the present invention (prepared in embodiment one) of the same specification, the polypropylene infusion bottle, and the three-layer co-extrusion film infusion bag are filled with sodium chloride injection (100ml, 0.9g) respectively, and in a corrugated box of the same specification The above samples were placed neatly respectively, 100 bags (bottles) per case, 40 cases per layer, 5 layers in total, 200 cases in total, and the above three samples were respectively placed in the car for long-distance transportation test.

[0045] The samples were sent from Xindu District, Chengdu to Urumqi, Xinjiang from November 15, 2010, and returned immediately after arriving, and returned to Xindu District, Chengdu, where the company is located, on December 8, 2010. The round trip took about 24 days in total.

[0046]Detection method: After transportation, ...

experiment example 3

[0050] Experimental example three, the biological inspection of the transfusion bag of the present invention

[0051] The infusion bag of the present invention (prepared in Example 1) was tested according to the United States Pharmacopoeia USP32 and the standards of YBB00012003, YBB00032003, and YBB00052003. The test results met the requirements of the above standards. The test results are shown in Table 3.

[0052] Table 3, biological test report of the present invention

[0053] serial number

[0054] 2

[0055] The following experimental examples and examples are used to further illustrate but not limit the present invention.

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Abstract

The invention relates to a transfusion bag with a self-contraction function and a transfusion bag special material thereof. The transfusion bag special material comprises the following materials: medical-grade high temperature resistant polypropylene, a medical-grade polyolefin elastomer, an anti-oxidant, and an acid scavenger. The manufacturing process of the transfusion bag of the invention comprises the following steps: weighing according to the formula; well mixing the raw materials; performing extrusion granulation by a double screw extruder, cooling with circulating water, drying in the air, and cutting granules mechanically. According to the transfusion bag special material of the invention, a POE elastomer is added into the raw materials, which increases the flexibility of the transfusion bag, and provides the self-contraction function for the transfusion bag which is produced by injection molding, stretching, blow molding technology and has an elliptic cross section; the bag prepared by the transfusion bag special material of the invention has no soldering joint, which greatly reduces the risk of liquid leakage.

Description

technical field [0001] The invention relates to an infusion bag capable of providing self-shrinking function and special materials for the infusion bag. Background technique [0002] Medical non-PVC (polyvinyl chloride) infusion soft bags are mainly made of three-layer or five-layer co-extrusion film through high-temperature heat sealing. At present, three-layer co-extrusion infusion film or five-layer co-extrusion infusion film mainly depends on imports, and the bag body is formed The post-welding part is prone to liquid leakage, especially the part where the infusion interface is welded; in addition, the three-layer or five-layer co-extruded infusion film layers are usually bonded by adhesives, which poses a potential contamination risk to the liquid in the bag; Each layer of film is generally added with benzene-containing elastomers (such as SEB, etc.) to achieve the effect of softening, but this also increases the safety risk of the infusion bag. [0003] Existing speci...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L23/12C08L23/08C08K5/134C08K3/26B29C49/06B29B9/06
Inventor 佘佑廷田洪伍冉良骥
Owner SICHUAN KELUN PHARMA RES INST CO LTD
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