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Method for estimating stress and strain of coronary artery blood vessel wall

A coronary artery and blood vessel wall technology, applied in the field of coronary artery blood vessel wall stress and strain, can solve problems such as difficult to obtain estimation and limit clinical wide application, and achieve the effect of reducing application conditions and simple algorithm

Inactive Publication Date: 2013-07-10
NORTH CHINA ELECTRIC POWER UNIV (BAODING)
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Problems solved by technology

Estimates of smaller strains in the shorter end-diastolic interval are difficult to obtain due to the low signal-to-noise ratio of the RF signal
At the same time, the basic signal of IVUS is converted into a conventional grayscale image displayed by the standard, and not all IVUS imaging systems allow the acquisition of raw radio frequency signals, thus limiting the wide clinical application of this method

Method used

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  • Method for estimating stress and strain of coronary artery blood vessel wall
  • Method for estimating stress and strain of coronary artery blood vessel wall
  • Method for estimating stress and strain of coronary artery blood vessel wall

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Experimental program
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Embodiment Construction

[0035] The processing steps of the present invention are described in detail below:

[0036] (1) Remove the image background:

[0037] The front and back frames of the IVUS image sequence are very similar, and the background area is basically the same, as shown in the attached figure 1 (a) shown. In order to reduce the calculation amount of subsequent steps, it needs to be removed. First, transform the horizontal view of each frame into the polar coordinate system to obtain the polar coordinate view (attached figure 1 (b)); then, since the background area is located below the polar coordinate view, set the background gray level in the polar coordinate view to 255 according to the following formula (attached figure 1 (c)):

[0038] (1)

[0039] in, r and θ are the polar diameter and polar angle of the pixel, respectively; I ( r , θ )and I' ( r , θ ) are the pixels in the polar coordinate view before and after removing the background ( r ,...

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Abstract

Disclosed is a method for estimating stress and strain of coronary artery blood vessel wall. According to the technical scheme, the method includes: firstly, acquiring a motion field of blood vessel wall tissues generated with blood pressure changes from an IVUS (intravascular ultrasound) gray scale image sequence; and secondly obtaining stress and strain values of points on blood vessel wall cross-section images of each frame. The stress and strain values of the blood vessel wall are directly obtained from the conventional IVUS gray scale image sequence, the algorithm is simple, and application conditions of the method are lowered. By the method compared with the methods based on radiofrequency signal analysis, strain values (including two master strains and a shear strain) of optional-direction points on the blood vessel cross section of each frame image can be calculated, elasticity of the blood vessel wall and plaque tissues can be reflected more comprehensively, and more reliable basis is provided for the analysis on pathogenesis of coronary arterial atherosclerosis, the estimation on vulnerability of atherosclerotic plaque, the prediction on development tendency of the atherosclerotic plaque and the like.

Description

technical field [0001] The invention relates to a method for estimating coronary artery wall stress and strain introduced by blood flow according to intravascular ultrasonic image sequences, belonging to the technical field of medical imaging. Background technique [0002] Coronary atherosclerotic plaque rupture and thrombosis are the main pathogenesis of acute coronary syndrome. The location of plaque rupture is related to the stress in and near the plaque. The relevant mechanical properties of coronary artery walls and plaques can be used as evaluation indicators for early detection of atherosclerosis and screening of unstable plaques. [0003] Intravascular ultrasound (IVUS) imaging is a minimally invasive interventional imaging technique widely used clinically to diagnose vascular lesions, especially coronary heart disease, and to detect vulnerable plaques. It provides cross-sectional images of blood vessel walls, lumens and plaques in vivo, and the deformation of coro...

Claims

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Application Information

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IPC IPC(8): A61B8/08
Inventor 孙正刘存王健健
Owner NORTH CHINA ELECTRIC POWER UNIV (BAODING)
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