Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for preparing postoperative drug for esophageal achalasia

A technique for achalasia and esophagus, which is applied in the field of preparation of postoperative medication for esophageal achalasia, can solve problems such as the inability to improve esophageal reflux, and achieve the effects of improving esophageal tension imbalance, being convenient to take, and increasing the burden on the liver and kidneys.

Inactive Publication Date: 2013-07-10
庞大斌
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After endoscopic treatment, the recurrence rate is relatively high, and after surgery, esophageal achalasia is controlled, but esophageal reflux cannot be improved
Therefore, there is currently a lack of a drug for improving esophageal relaxation imbalance after endoscopic treatment of esophageal achalasia and surgical treatment

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Example 1, the weight ratio of raw materials: 10 parts of litchi core, 6 parts of upland grass, 3 parts of poria cocos, 6 parts of tangerine peel, 3 parts of stalk grass, 6 parts of genus vine, 6 parts of kudzu root, 6 parts of aescin, 6 parts of loofah, 1 part of pangolin, 3 parts of burnt malt, 10 parts of burnt grain sprouts.

Embodiment 2

[0034] Example 2, the weight ratio of raw materials: 20 parts of litchi core, 10 parts of upland grass, 6 parts of Poria cocos, 10 parts of dried tangerine peel, 6 parts of stalks, 10 parts of terrazzo, 10 parts of kudzu root, 10 parts of Aescin, 10 parts of loofah, 2 parts of pangolin, 6 parts of burnt malt, 20 parts of burnt grain sprouts.

Embodiment 3

[0035] Example 3, the weight ratio of raw materials: 30 parts of litchi core, 12 parts of upland grass, 10 parts of poria cocos, 12 parts of tangerine peel, 10 parts of stalk grass, 12 parts of terrazzo, 12 parts of kudzu root, 12 parts of Aescin, 12 parts of loofah, 5 parts of pangolin, 10 parts of burnt malt, 25 parts of burnt grain sprouts.

[0036] The Chinese medicine of embodiment 1~3 can be prepared by the following method:

[0037] (1) Extract the volatile oil from pueraria puerariae, upland grass, and stalk grass powder by steam distillation, and collect and mix for later use;

[0038] (2) Grind burnt grain buds and burnt malt through a 150-mesh sieve to form fine powder for later use;

[0039] (3) Mix lychee core, poria cocos, dried tangerine peel, terrazzo vine, loofah, aescin and pangolin, add 10 times the amount of water, add water and decoct twice for 1 hour each time, combine the decoction, and let it stand; Add 3~4 times of 95% ethanol to the decoction, let i...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for preparing a postoperative drug for esophageal achalasia. The drug is applied to the treatment of esophageal achalasia. The drug is characterized by being prepared from the following raw pharmaceutical materials in proportioning ratio by weight: litchi chinensis Sonn., lindernia ruellioides (Colsm.) Pennell, poriacocos (Schw.) Wolf, citrus reticulata Blanco, aeschynomene indica L., trachelospermum jasminoides (Lindl.) Lem., radix puerariae, paris polyphylla Sm., luffa cylindrica (L.) Roem., manis pentadactyla Linnaeus, hordeum vulgare L. and setaria italica (L.) Beauv.. The method comprises the following steps of: (1) extracting volatile oil from coarse powder of radix puerariae, lindernia ruellioides (Colsm.) Pennell and aeschynomene indica L. for later use; (2) crushing setaria italica (L.) Beauv. into fine powder for later use; (3) carrying out water extraction and alcohol precipitation on litchi chinensis Sonn., poriacocos (Schw.) Wolf, citrus reticulata Blanco, trachelospermum jasminoides (Lindl.) Lem., luffa cylindrica (L.) Roem., paris polyphylla Sm., manis pentadactyla Linnaeus and hordeum vulgare L., and drying so as to obtain a preliminary material; and (4) spraying the volatile oil into the preliminary material, adding the fine powder of setaria italica (L.) Beauv., uniformly mixing, sieving by using a 60-mesh sieve, and encapsulating. Proved by clinical trials, the drug prepared by the method has the characteristics of good treatment effect and high safety in the postoperative treatment of esophageal achalasia, so that the method is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a preparation method for postoperative medication for achalasia of the esophagus. Background technique [0002] Esophageal achalasia is a primary total esophageal motility disorder characterized by ① no peristalsis in the esophageal body. ② When swallowing, the lower esophageal sphincter does not relax or does not relax completely. ③The lower esophageal sphincter pressure increases at rest. Although achalasia is a benign disease, it has a great impact on quality of life, health and longevity. Due to dysphagia, patients can use all measures, including body position, drinking water, repeated swallowing and other measures, so that patients are ashamed to eat in front of everyone and prefer to eat alone, causing psychological pressure and seriously affecting social activities. The cause of this disease is unknown. It may be related to toxins, nutritional deficiencies,...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/8998A61K9/48A61P1/00A61K35/36
Inventor 庞大斌
Owner 庞大斌
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com