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Cordyceps sinensis soft capsule and preparation method thereof

A technology of Cordyceps sinensis and soft capsules, which is applied in the field of Cordyceps sinensis soft capsules and its preparation, can solve the problems of loss and easy destruction of active ingredients, and achieve the effects of increasing content, reducing dosage, and improving curative effect

Active Publication Date: 2013-08-14
SHANGHAI TONGJI BIOLOGICAL PROD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] In addition, the contents of existing soft capsules are mostly powder and oily esters. During the process of high temperature, drying, crushing, etc., the active ingredients contained in them are easily destroyed and lead to loss.

Method used

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  • Cordyceps sinensis soft capsule and preparation method thereof
  • Cordyceps sinensis soft capsule and preparation method thereof
  • Cordyceps sinensis soft capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] A kind of Cordyceps sinensis soft capsule, the content of this soft capsule is made up of following components by weight percentage:

[0042]

[0043] The preparation method of above-mentioned Cordyceps sinensis soft capsule, carries out as follows:

[0044] (1) fully enzymatically hydrolyze the Cordyceps sinensis extract and the Cordyceps mycelium extract: adjust the pH of the extract to 4.5, and the temperature to 50° C., add enzyme for enzymolysis for 1 hour, and then inactivate the enzyme;

[0045] (2) Production of soft capsules: control temperature at 25±2°C, humidity at 45%±5%, including batching, mixing, emulsification, sol, and pill pressing, proceed as follows:

[0046] (1) Fully mix the Cordyceps sinensis extract and Cordyceps mycelium extract that require water-in-oil and Ganoderma lucidum spore oil according to the formula quantity, and the mixing time is 20 minutes;

[0047] (2) Add an emulsifier that can emulsify into a water-in-oil emulsion according...

Embodiment 2

[0055] A kind of Cordyceps sinensis soft capsule, the content of this soft capsule is made up of following components by weight percentage:

[0056]

[0057] The preparation method of above-mentioned Cordyceps sinensis soft capsule, carries out as follows:

[0058] (1) Fully enzymolyze the Cordyceps sinensis extract and the Cordyceps mycelium extract: adjust the pH of the extract to 4, the temperature to 55° C., add enzyme to enzymolyze for 1.2 hours, and then inactivate the enzyme;

[0059] (2) Production of soft capsules: control temperature at 25±2°C, humidity at 45%±5%, including batching, mixing, emulsification, sol, and pill pressing, proceed as follows:

[0060] (1) Fully mix the Cordyceps sinensis extract and Cordyceps mycelium extract that require water-in-oil and Ganoderma lucidum spore oil according to the formula quantity, and the mixing time is 30 minutes;

[0061] (2) Add an emulsifier that can emulsify into a water-in-oil emulsion according to the formula, s...

Embodiment 3

[0069] A kind of Cordyceps sinensis soft capsule, the content of this soft capsule is made up of following components by weight percentage:

[0070]

[0071] The preparation method of above-mentioned Cordyceps sinensis soft capsule, carries out as follows:

[0072] (1) Fully enzymolyze the Cordyceps sinensis extract and the Cordyceps mycelium extract: adjust the pH of the extract to 5, the temperature to 45° C., add enzyme to enzymolyze for 1.5 hours, and then inactivate the enzyme;

[0073] (2) Production of soft capsules: control temperature at 25±2°C, humidity at 45%±5%, including batching, mixing, emulsification, sol, and pill pressing, proceed as follows:

[0074] (1) Fully mix the Cordyceps sinensis extract and Cordyceps mycelium extract that require water-in-oil and Ganoderma lucidum spore oil according to the formula quantity, and the mixing time is 40 minutes;

[0075] (2) Add an emulsifier that can emulsify into a water-in-oil emulsion according to the formula, s...

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Abstract

The invention provides a cordyceps sinensis soft capsule and a preparation method thereof. The soft capsule comprises 24-28% of cordyceps sinensis extracting solution after enzymolysis, 25-32% of cordyceps sinensis mycelia extracting solution after enzymolysis, 40-48% of ganoderma lucidum spore oil and 3-5% of water-in-oil emulsifier. The preparation method of the soft capsule comprises the following steps of: (A) carrying out enzymolysis for 1-1.5 hours under the conditions that the pH value is 4-5 and the temperature is 45-55 DEG C; and (B) preparing the soft capsule by controlling the temperature at 25+ / -2 DEG C and the humidity at 45%+ / -5%: (1) fully mixing the cordyceps sinensis extracting solution and the ganoderma lucidum spore oil; (2) adding the emulsifier for stirring and emulsifying, and treating by a colloid mill; (3) dissolving; and (4) pelleting. According to the invention, the cordyceps sinensis extracting solution and the ganoderma lucidum spore oil are matched reasonably so as to form the water-in-oil emulsion in which a ganoderma lucidum spore oil film is coated outside the cordyceps sinensis extracting solution, thereby avoiding oil leakage; by carrying out enzymolysis on the cordyceps sinensis extracting solution, inactive substances in the cordyceps sinensis extracting solution are changed to active substances; and the cordyceps sinensis extracting solution is directly used, thereby avoiding the loss of active components and increasing the contents of functional components.

Description

technical field [0001] The invention belongs to the technical field of health food, and relates to a soft capsule of Cordyceps sinensis and a preparation method thereof. Background technique [0002] There are currently two traditional methods for preparing soft capsules: one is directly prepared from extracts. Another method is prepared from dry paste powder. The components of these two methods are relatively single, and the curative effect is limited. [0003] The soft capsule is made of gelatin and cannot be exposed to water. After contact with water, the rubber will melt and the content will be lost and softened so that the final shape cannot be formed. Therefore, the content of the soft capsule is emulsified to convert it into a water-in-oil emulsified form to prevent the soft capsule rubber. melt. [0004] The water-in-oil emulsified form has been widely used in cosmetics, pharmaceutical ointments and other related industries. But this kind of technology is not app...

Claims

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Application Information

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IPC IPC(8): A61K36/074A61K9/48A61P37/02A61P35/00A61P3/10A61P1/16A61P11/00A61P13/12A61P37/08A61P9/00
Inventor 桂仁斌王云华马福全
Owner SHANGHAI TONGJI BIOLOGICAL PROD
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