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Natural pharmaceutical composition

A technology of natural medicines and compositions, applied in drug combinations, antineoplastic drugs, pharmaceutical formulations, etc., can solve the problems of patients with dehydration, acid-base balance disorders, malnutrition, etc. Good results

Inactive Publication Date: 2013-09-18
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural pharmaceutical composition

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Experimental program
Comparison scheme
Effect test

Embodiment approach

[0032] The first step: preparation of various extracts

[0033] (1) Preparation of Concentrated Extract of Artemisia argyi Ume Water Decoction

[0034] According to the compatibility ratio of 1-4:1, take mugwort leaves and black plums, soak them in distilled water, heat and decoct for 1 hour, filter them with silk cloth, add distilled water to the medicinal residues, soak, decoct, and filter them in the same way, mix the two filtrates, heat and concentrate, Ultrafiltration membrane filtration, drying under reduced pressure, that is.

[0035] (2) Preparation of Artemisia argyi ethyl acetate extract

[0036] An appropriate amount of Artemisia argyi leaves is extracted with 95% ethanol, and the solvent is recovered to obtain an alcohol extraction extract. The extract is extracted with n-hexane, and then extracted with ethyl acetate, and the obtained ethyl acetate extract is recovered with a solvent to obtain the product.

[0037] (3) Preparation of ebony ethanol extract

[003...

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Abstract

The invention relates to a natural pharmaceutical composition, a preparation method thereof and application thereof in preparation of toxicity reducing and efficacy enhancing drugs for cancer chemotherapy. The natural pharmaceutical composition is prepared from a folium artemisiae argyi and black plum decoction concentrated extract, a folium artemisiae argyi ethyl acetate extract and a black plum ethanol extract which are in the ratio of (2-8): (4-5): (3-7), has an excellent treatment effect on cancer chemotherapy-associated diarrhea, and can simultaneously play a role in synergizing the cancer chemotherapy.

Description

technical field [0001] The present invention relates to a kind of natural medicinal composition, more specifically relate to a kind of natural medicinal composition that is composed of Artemisia argyi ebony decoction concentrated extract, ethyl acetate extract of Artemisia argyi leaf and ethanol extract of Ume ume, the preparation of the natural medicinal composition The method and the use of the natural medicine composition in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61P1/12A61P35/00A61K36/282
Inventor 石强
Owner 石强
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