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Traditional Chinese medicine preparation and application thereof
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A technology of traditional Chinese medicine preparations and drugs, applied in the fields of medicine and biology, to improve the effect of treating and preventing diabetes and inhibiting overexpression
Active Publication Date: 2014-11-05
CANVEST WUHAN BIOTECH
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Problems solved by technology
Although the development of modern science allows people to produce drugs for the treatment of diabetes through synthetic methods, natural herbal medicines still occupy an important position in the prevention and treatment of diabetes, and have an irreplaceable role for synthetic drugs.
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Embodiment 1
[0104] A kind of traditional Chinese medicine preparation, is formulated by weight part by following component:
[0105]
[0106] The preparation method of this Chinese medicine preparation, its step is:
[0107] The botanical composition provided by the present invention is prepared from the above-mentioned plant extracts. The specific preparation process is: according to the above ratio, weigh 16 grams of Coptidis Rhizoma, 8 grams of Scutellaria baicalensis, 18 grams of Astragalus membranaceus, 10 grams of Lycium barbarum, 10 grams of Rhizoma Chuanxiong, and betel nuts. 10 grams, 8 grams of Gynostemma pentaphyllum, 10 grams of Sophora flavescens, 10 grams of green tea leaves, crushed, put in a 1000ml beaker, add 10 times the amount of water (1000ml) and soak for 0.5 hours, first use strong fire, after boiling, then simmer for 0.5 hours, Filter through four layers of gauze, add 500ml of purified water to the filter residue, repeat the above steps, combine the filtrate twic...
Embodiment 2-8
[0109] The preparation method of Examples 2-8 is the same as that of Example 1 except that the distribution ratio of each component is different.
[0110] components
Embodiment 9
[0111] Embodiment 9: the application of a kind of traditional Chinese medicine preparation in the preparation treatment and prevention of diabetes, its application process is:
[0112] The Chinese medicine preparation used in this example is the Chinese medicine preparation prepared in Example 1.
[0113] At the initial stage of hyperglycemia induced by the injection of alloxan, that is, two days after the injection, traditional Chinese medicine preparations were used to treat diabetes, and routine diabetes examinations and molecular level examinations were followed up.
[0114] (1) Select 30 healthy, mature mice with a body weight of 24-26g, and set up 20 mice each in the normal group, diabetes group, and Chinese medicine treatment diabetes group. The treatment methods are as follows:
[0116] Diabetes group: the mice were fasted for 16 hours, injected with alloxan normal saline solution 140 mg / kg into the tailvein, and the fa...
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Abstract
The invention discloses a traditional Chinese medicine preparation and an application thereof. The traditional Chinese medicine preparation is prepared by compounding coptis chinensis, scutellaria baicalensis, astragalus membranaceus, lycium barbarum, ligusticum wallichii, arecacatechu, gynostemma pentaphylla, radix sophorae flavescentis and green tea in proportion. The raw materials are obtained easily; and a preparation method is simple, so that the traditional Chinese medicine is suitable for large-scale production. When the traditional Chinese medicine is applied to a mice test, by detecting an insulinpromoter factor 1 (IPF-1) and a p53 cancergene via an molecular biology method, the fact that the traditional Chinese medicine is capable of inhibiting the excessive expression of the cancergene is discovered, so that the effects of the traditional Chinese medicine for treating and preventing diabetes are realized. Thus, the traditional Chinese medicine can play an important role in preventing diabetes complications.
Description
technical field [0001] The invention relates to the technical fields of biology and medicine, in particular to a traditional Chinese medicine preparation, the application of the traditional Chinese medicine preparation in the preparation of medicines for treating and preventing diabetes, and the application of the traditional Chinese medicine preparation in down-regulating the expression of p53 oncogene mRNA. Background technique [0002] Diabetes is a metabolic disease related to abnormal insulin production and action and characterized by hyperglycemia, including type 1 diabetes mainly characterized by absolute insulin deficiency and type 2 diabetes characterized by relative insulin deficiency and insulin resistance. Two types of diabetes. At present, diabetes has become the third major chronic disease that seriously endangers human health after cardiovascular and cerebrovascular diseases and tumors in the world. Diabetes is one of the chronic diseases recognized in the wo...
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Application Information
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