Combined drug of rhodiola rosea extract, medlar extract and sea-buckthorn fresh pulp powder extract as well al preparation and application thereof

A wolfberry extract and extract technology are applied in the direction of drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, which can solve the problems of difficult preservation of seabuckthorn fresh pulp, and achieve stable and controllable quality of preparations, clear ingredients, Improve the effect of curative effect

Active Publication Date: 2013-09-25
GANSU CHEEZHENG TIBETAN MEDICINE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

1. Through the research on the effective parts of Rhodiola rosea, Lycium barbarum, and seabuckthorn fresh pulp medicinal materials, the salidroside components in Rhodiola rosea were extracted by 70% ethanol reflux method; Lycium barbarum was extracted by water extraction and alcohol precipitation method The active ingredient of crude polysaccharides from Lycium barbarum; because seabuckthorn fresh pulp is harvested seasonally, the fresh seabuckthorn pulp is passed through an 80-mesh sieve and then concentrated, dried and crushed for storage, which solves the problem that seabuckthorn fresh pulp is not easy to preserve, and provides for perennial production. The original medicinal materials were extracted, and the flavonoids, the main active parts of seabuckthorn fresh pulp, were extracted with 70% ethanol

Method used

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  • Combined drug of rhodiola rosea extract, medlar extract and sea-buckthorn fresh pulp powder extract as well al preparation and application thereof
  • Combined drug of rhodiola rosea extract, medlar extract and sea-buckthorn fresh pulp powder extract as well al preparation and application thereof
  • Combined drug of rhodiola rosea extract, medlar extract and sea-buckthorn fresh pulp powder extract as well al preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Prescription (recipe 7):

[0036] Rhodiola rosea extract (containing salidroside 8.64mg×1000) 644g

[0037] Lycium barbarum extract (containing Lycium barbarum polysaccharide 3.25mg×1000) 85g

[0038] Sea buckthorn fresh juice powder extract (containing total flavonoids 1.931mg×1000) 9.66g

[0039] Preparation method: Weigh Rhodiola rosea extract, Lycium barbarum extract and seabuckthorn fresh juice powder extract according to the prescription, add appropriate amount of auxiliary materials, mix evenly, and fill in capsules to obtain 1000 capsules.

[0040]

Embodiment 2

[0042] Prescription (recipe 7):

[0043] Rhodiola rosea extract (containing salidroside 8.64mg×1000) 644g

[0044] Lycium barbarum extract (containing Lycium barbarum polysaccharide 3.25mg×1000) 85g

[0045] Sea buckthorn fresh juice powder extract (containing total flavonoids 1.931mg×1000) 9.66g

[0046] Beeswax 45g

[0047] Appropriate amount of gelatin

[0048] Appropriate amount of glycerin

[0049] Paraffin oil amount

[0050] Preparation method: take beeswax, dissolve it with slight heat, add rhodiola rosea extract, medlar extract, seabuckthorn fresh juice powder extract and paraffin oil and other suitable excipients, stir well, colloid mill to grind evenly, degas under reduced pressure, The medicine is hydraulically processed into 1000 soft capsules.

[0051]

Embodiment 3

[0053] Prescription (recipe 7):

[0054] Rhodiola rosea extract (containing salidroside 8.64mg×1000) 644g

[0055] Lycium barbarum extract (containing Lycium barbarum polysaccharide 3.25mg×1000) 85g

[0056] Sea buckthorn fresh juice powder extract (containing total flavonoids 1.931mg×1000) 9.66g

[0057] Sucrose 600g

[0058] Starch 350g

[0059] 60g beaten starch

[0060] Fragrance 2ml

[0061] Preparation method: Weigh the prescription amount of rhodiola rosea extract, wolfberry fruit extract, seabuckthorn fresh juice powder extract, sucrose and starch, crush them through a 100-mesh sieve, and mix them thoroughly for half an hour; wash the beaten starch into 10% starch pulp, and set aside to cool. Add the starch slurry to the mixed material under stirring to make a soft material, pass through a 14-mesh sieve, and make wet granules. The wet granules were dried at 55°C for 3 hours, sprayed with essence after whole granules, left to stand for half an hour, and divided i...

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Abstract

The invention provides a combined drug of rhodiola rosea extract, medlar extract and sea-buckthorn fresh pulp powder extract as well al preparation and an application thereof, relates to an extraction and combination method and a preparation method of a medicinal preparation and in particular relates to an extraction and combination method of rhodiola rosea extract, medlar extract and sea-buckthorn fresh pulp powder extract and a preparation of rhodiola rosea extract, medlar extract and sea-buckthorn fresh pulp powder extract. The combined drug is composed of rhodiola rosea extract, medlar extract and sea-buckthorn fresh pulp powder extract, wherein weight ratio of rhodiola rosea extract to medlar extract to sea-buckthorn fresh pulp powder extract is (322-644):(85-340):(2.41-9.66). Salidroside content in rhodiola rosea extract is not less than 1.2%, lycium barbarum polysaccharide content in medlar extract, metered by glucose, is not less than 3.5%, and total flavone content in sea-buckthorn fresh pulp powder extract, metered by rutin, is not less than 20.0%. Each dose unit of the prepared combined drug of rhodiola rosea extract, medlar extract and sea-buckthorn fresh pulp powder extract contains 4.32-8.64mg of salidroside, 3.25-12.99mg of lycium barbarum polysaccharide and 0.483-1.931mg of total flavone.

Description

technical field [0001] The invention relates to a combination medicine of rhodiola rosea extract, medlar fruit extract and seabuckthorn fresh pulp powder extract and its preparation and application, relating to the extraction, combination method and preparation method of a medicine preparation, more specifically, to a The invention relates to the extraction and combination methods of rhodiola rosea extract, medlar fruit extract and seabuckthorn fresh juice powder extract and their preparations. Background technique [0002] Commodities such as Youxinnaoxin Capsules are made from Rhodiola rosea, Lycium barbarum and Seabuckthorn fresh pulp after proper processing, and its quality standard is WS-10628(ZD-0628)-2002; its function is to nourish qi and nourish yin, promote blood circulation and remove blood stasis; For dizziness, headache, heart palpitations, asthma, fatigue caused by deficiency of qi and yin, stagnation of blood stasis; polycythemia caused by hypoxia. [0003] R...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61P1/14A61P7/00A61P9/10
Inventor 邹存生马俊仓吴留强夏彬张国清
Owner GANSU CHEEZHENG TIBETAN MEDICINE CO LTD
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