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Traditional Chinese medicine for treating chilblain and preparation method thereof

A frostbite and traditional Chinese medicine technology, applied in the field of biomedicine, can solve problems such as unfavorable patient use, insufficient process parameters, poor product stability, etc., and achieve the effects of avoiding water waste, rational and scientific combination, and stability improvement.

Active Publication Date: 2014-01-08
黄荣 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This patent discloses a traditional Chinese medicine preparation for treating mild and severe frostbite and its production method. 30. Gallnut 8-15", the production process adopts the traditional water extraction and concentration process, the product stability is poor, and there is continuous precipitation during the placement process, resulting in too much sediment in the solution, which is not conducive to the use of patients, and is extremely It has greatly affected the stability of the product; moreover, the process route is relatively extensive, the auxiliary materials are not specified in detail, and the process parameters are not enough, which is not conducive to the consistency of quality between multiple batches of products

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Yanhuanglian 200g Ephedra 150g Guizhi 150g

[0047] Fangfeng 100g Nepeta 100g Safflower 30g

[0048] (1) Take component A of ZTCI+1 natural clarifier and prepare a solution with a concentration of 1% by weight with water to obtain solution 1, and component B with 1% acetic acid to prepare a solution with a concentration of 1% by weight to obtain Solution 2;

[0049] (2) Crush all medicinal materials into coarse powder, extract twice, add 5840g of water for the first time, extract for 1 hour, filter, add 5840g of water for the second time, extract for 1 hour, filter, combine the two filtrates , concentrated to 1460g, filtered to obtain solution 3;

[0050] (3) Heat solution 3 to 70°C, add 58.4g of solution 2, stir evenly, then stir once every 20 minutes, after 2 hours, add 20.2g of solution 1, stir evenly, stand for 2 hours, high speed Centrifuge to separate the precipitate, and take the supernatant to obtain the active ingredient.

Embodiment 2

[0052] Yanhuanglian 500g Ephedra 400g Guizhi 400g

[0053] Fangfeng 300g Nepeta 300g Safflower 100g

[0054] (1) Take component A of ZTCI+1 natural clarifier and prepare a solution with a concentration of 1% by weight with water to obtain solution 1, and component B with 1% acetic acid to prepare a solution with a concentration of 1% by weight to obtain Solution 2;

[0055] (2) Crush all medicinal materials into coarse powder, extract twice, add 24000g of water for the first time, extract for 1 hour, filter, add 24000g of water for the second time, extract for 1 hour, filter, combine the two filtrates , concentrated to 4350g, filtered to obtain solution 3;

[0056] (3) Heat solution 3 to 90°C, add 348g of solution 2, stir evenly, then stir once every 20 minutes, after 2 hours, add 174g of solution 1, stir evenly, let stand for 2 hours, and centrifuge at high speed, Separating the precipitate and taking the supernatant to obtain the active ingredient;

[0057] (4) Dilute th...

Embodiment 3

[0059] Yanhuanglian 300g Ephedra 150g Guizhi 200g

[0060] Fangfeng 150g Nepeta 150g Safflower 50g

[0061] (1) Take component A of ZTCI+1 natural clarifier and prepare a solution with a concentration of 1% by weight with water to obtain solution 1, and component B with 1% acetic acid to prepare a solution with a concentration of 1% by weight to obtain Solution 2;

[0062] (2) Crush all medicinal materials into coarse powder, extract twice, add 10000g of water for the first time, extract for 1 hour, filter, add 8000g of water for the second time, extract for 1 hour, filter, combine the two filtrates , concentrated to 3000g, filtered to obtain solution 3;

[0063] (3) Heat solution 3 to 90°C, add 180g of solution 2, stir evenly, then stir once every 20 minutes, after 2 hours, add 100g of solution 1, stir evenly, let stand for 2 hours, and centrifuge at high speed, Separating the precipitate and taking the supernatant to obtain the active ingredient;

[0064] (4) Dilute the ...

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Abstract

The invention discloses a traditional Chinese medicine for treating chilblain and a preparation method thereof. The traditional Chinese medicine comprises corydalis thalictrifolia, Chinese ephedra, cassia twig, radices sileris, tenuifolia and flowers carthami. The traditional Chinese medicine disclosed by the invention is good in curative effect on the chilblain and free of toxic and side effects. Process optimization is also carried out; the optimized process adopts a clarifying agent treatment process; excessive water resource waste is avoided; technological parameters are clear, so that the stability of the prepared product is greatly improved; the variety and the dosage of auxiliary materials are clear; the quality of the finally prepared and molded product is improved; the uniformity of the quality of a plurality of batches of products is ensured.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a traditional Chinese medicine for treating frostbite and a preparation method thereof. Background technique [0002] Frostbite refers to the systemic or local injury caused by the invasion and attack of the human body by cold evil. Frostbite is caused by cold weather and mostly occurs on the extremities of the hands and feet, the tip of the nose, cheeks and ears. The affected skin is pale, red, edema, itchy, hot, and swollen. In severe cases, purple blood blisters may cause necrosis of the affected area, ulceration, pus and pain. The condition of local frostbite patients is relatively mild, with local swelling, numbness, itching, bruising, or blisters, and even ulceration and sores. [0003] Chinese patent, name: "Traditional Chinese medicine preparation for treating mild and severe frostbite and its production method", patent application number: "201110195170.6". This patent disc...

Claims

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Application Information

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IPC IPC(8): A61K36/66A61P17/02
Inventor 黄荣黄宣霖
Owner 黄荣
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