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Foaming agent for vaginal packing

A foam and vaginal technology, applied in the direction of antifungal agents, aerosol delivery, antibacterial drugs, etc., can solve the problems of destroying the pH value of the vagina, reverse infection, and inability to penetrate deeply, so as to enhance immune function and restore disease resistance , good therapeutic effect

Active Publication Date: 2014-01-22
NANJING YAFANG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Traditional gynecological products are mainly lotions, tablets, suppositories, gels, and effervescent tablets. It is difficult to effectively achieve the sterilization time and site. Antibiotics, lotions, suppositories, and gels are often used, which damages the vaginal The pH value changes the weak acid environment of the vagina, and it can also bring bacteria from the vaginal opening into the deep vagina, causing reverse infection and gynecological inflammation
Due to the folds of the vagina itself, ordinary treatments, including drugs and physical therapy, can only reach the surface of the vaginal wall and cannot penetrate deep into the vaginal folds. The therapeutic effect is short-term. After a period of time, the pathogenic bacteria in the vaginal folds Reactivation, reproduction, recurring gynecological inflammation

Method used

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  • Foaming agent for vaginal packing
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Experimental program
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Effect test

Embodiment Construction

[0012] Formula: (weight ratio)

[0013]

[0014] Propellant: n-butane, isobutane and / or n-propane 2-15; or dimethyl ether 5-20; or fluoroalkane 2-15; or Freon 5-15. .

[0015] Preparation of silver-supported zirconium phosphate

[0016] The preparation method of silver-loaded zirconium phosphate: first prepare a zirconium phosphate carrier of 400-1000nm, then mix the zirconium phosphate carrier with an aqueous solution of zinc nitrate, stir to form a zinc-loaded intermediate; prepare the zinc-loaded intermediate into a water dispersion, and add silver nitrate solution, so that the content of silver ions in the carrier is 1.5% to 3.5%, stirring, washing, filtering, drying and calcining to obtain the final product.

[0017] Preparation method of vaginal packing foam

[0018] Put the carbomer into a vacuum stirring pot first, add glycerin and propylene glycol to stir, add purified water to swell for 24-48 hours, add triethanolamine and stir to prepare a transparent gel, add...

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PUM

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Abstract

The invention discloses a foaming agent for vaginal packing. Raw materials for the foaming agent comprise, by weight, 0.1 to 2.0 parts of carbomer, 1.0 to 3.0 parts of zirconium phosphate-loaded silver or nanometer silver, 1.0 to 5.0 parts of glycerin, 1.0 to 5.0 parts of propylene glycol, 0.2 to 5.0 parts of triethanolamine, 96.69 to 78 parts of purified water, 0.01 to 2.0 parts of fibronectin (FN), 0.1 to 3.0 parts of paeonol and 0.1 to 3.0 parts of matrine. A propellant comprises 0 to 15 parts of n-butane, isobutane and / or n-propane, or 0 to 20 parts of dimethyl ether, or 0 to 15 parts of fluoroalkane, or 0 to 15 parts of Freon. According to results of clinical practice, therapeutic effects of the foaming agent provided by the invention are substantially superior to those of traditional therapy, and a treatment course needed in the invention is shorter than that of conventional therapy.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, in particular to a vaginal packing foam and a preparation method thereof. Background technique [0002] Traditional gynecological products are mainly lotions, tablets, suppositories, gels, and effervescent tablets. It is difficult to effectively achieve the sterilization time and site. Antibiotics, lotions, suppositories, and gels are often used, which damages the vagina. The pH value changes the weak acid environment of the vagina, and can also bring bacteria from the vaginal opening into the deep vagina, causing reverse infection and gynecological inflammation. Due to the folds of the vagina itself, ordinary treatments, including drugs and physical therapy, can only reach the surface of the vaginal wall and cannot penetrate deep into the vaginal folds. The therapeutic effect is short-term. After a period of time, the pathogenic bacteria in the vaginal folds Reactivation, reproduction...

Claims

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Application Information

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IPC IPC(8): A61K9/12A61K33/38A61P15/02A61P15/00A61P31/04A61P31/10
Inventor 徐克之
Owner NANJING YAFANG PHARMA CO LTD
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