Application of peptide compound in rhizoma sparganii
A compound and peptide technology, applied in the field of medicine, can solve the problems of active ingredients not being found, staying, and limiting the popularization and application of triangular compounds, and achieve the effect of filling the technical gap and improving anticoagulant activity
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0028] Example 1 Extraction, separation, purification and structural identification of compounds represented by formula (II)
[0029] 1. Experimental materials:
[0030] (1) medicinal materials
[0031] Trigonium medicinal material was purchased from Guangzhou Zhixin Pharmaceutical Co., Ltd., batch number 090301, and was identified as a plant of the genus Trigonum trigonum by the professor Li Shuyuan of the Chinese Medicine Identification Department of the School of Chinese Materia Medica of our school. Sparganium stoloniferum Buch.-Ham Dried tuber peeled off.
[0032] (2) Reagents and fillers
[0033] Chloroform (analytical grade, Tianjin Fuyu Fine Chemical Co., Ltd.);
[0034] Methanol (analytical pure, Tianjin Fuyu Fine Chemical Co., Ltd.);
[0035] Vanillin (Guangzhou Guanglianjin Chemical Factory);
[0036] Silica gel for column chromatography (80-100 mesh, 100-200 mesh, 200-300 mesh, Qingdao Ocean Chemical Factory);
[0037] Thin-layer chromatography silica gel (s...
Embodiment 2
[0068] Embodiment 2 Anticoagulant function test of compound described in the present invention
[0069] 1. Experimental materials
[0070] (1) Drugs
[0071] The cyclo-(phenylalanine-phenylalanine) prepared in Example 1.
[0072] (2) animals
[0073] SD rats, weighing 180-250 g, were provided by the Experimental Animal Center of Guangzhou University of Traditional Chinese Medicine.
[0074] (3) Reagents
[0075] Heparin (sigma, batch number: 20120509);
[0076] Chloral hydrate (Guangzhou Sile Biochemical Reagent Co., Ltd.);
[0077] Prothrombin time PT kit (Nanjing Jiancheng Institute of Bioengineering, batch number: 20130314);
[0078] Activated partial thromboplastin time APTT kit (Nanjing Jiancheng Bioengineering Institute, batch number: 20130201);
[0079] Thrombin time TT kit (Nanjing Jiancheng Institute of Bioengineering, batch number: 20130314);
[0080] Normal saline (Guizhou Tiandi Pharmaceutical Co., Ltd., batch number A13011209);
[0081] Dimethyl sulfoxide...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com