Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A method for detecting dioxane content in children's cosmetics

A technology for dioxane and cosmetics is applied in the field of detection of harmful substances in cosmetics, and achieves the effects of easy popularization and application, cost saving and improved detection sensitivity

Active Publication Date: 2017-02-01
FROG PRINCE (FUJIAN) BABY & CHILD CARE PROD CO LTD
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, in the prior art, there is no report on the use of surface-enhanced Raman spectroscopy to detect the content of dioxane in cosmetics

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A method for detecting dioxane content in children's cosmetics
  • A method for detecting dioxane content in children's cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A method for detecting the content of dioxane in children's cosmetics is carried out according to the following steps:

[0026] (1) Pretreat the sample to be tested to form a sample solution. The pretreatment of the sample to be tested can be processed by common methods, such as one or more of dissolution, extraction, micro-extraction, distillation and chromatography. Specifically, it can be carried out as follows: first, weigh 20 g of the sample to be tested, and accurately to 0.0001g; then pour the sample to be tested into a beaker filled with 100ml of ethanol, soak for 10h, then stir for 3h; finally, filter with suction, concentrate the filtrate to 5ml, and seal it for later use.

[0027] (2) Stir 20ml of an aqueous solution containing 1mM silver nitrate, 0.25mM sodium dodecylsulfonate and 1mM ethylenediaminetetraacetic acid in the container, and adjust the pH value of the aqueous solution to 11; then, add 50µL of 0 .1mol / L ascorbic acid solution, keep stirring for ...

Embodiment 2

[0036]A method for detecting the content of dioxane in children's cosmetics is carried out according to the following steps:

[0037] (1) Pretreat the sample to be tested to form a sample solution. The pretreatment of the sample to be tested can be processed by common methods, such as one or more of dissolution, extraction, micro-extraction, distillation and chromatography. Specifically, it can be carried out as follows: first, weigh 20 g of the sample to be tested, and accurately to 0.0001g; then pour the sample to be tested into a beaker filled with 100ml of ethanol, soak for 12h, then stir for 4h; finally, filter with suction, concentrate the filtrate to 5ml, and seal it for later use.

[0038] (2) Add 20ml of aqueous solution into the container and stir, the aqueous solution contains 1.2mM silver nitrate, 0.5mM sodium dodecylsulfonate and 0.8mM ethylenediaminetetraacetic acid, and adjust the pH value of the aqueous solution to 10; then, Add 50 µL of 0.5 mol / L ascorbic aci...

Embodiment 3

[0047] A method for detecting the content of dioxane in children's cosmetics is carried out according to the following steps:

[0048] (1) Pretreat the sample to be tested to form a sample solution. The pretreatment of the sample to be tested can be processed by common methods, such as one or more of dissolution, extraction, micro-extraction, distillation and chromatography. Specifically, it can be carried out as follows: first, weigh 20 g of the sample to be tested, and accurately to 0.0001g; then pour the sample to be tested into a beaker filled with 100ml of ethanol, soak for 18h, then stir for 5h; finally, filter with suction, concentrate the filtrate to 5ml, and seal it for later use.

[0049] (2) Add 20ml of aqueous solution into the container and stir, the aqueous solution contains 0.8mM silver nitrate, 1mM sodium dodecylsulfonate and 2mM ethylenediaminetetraacetic acid, and adjust the pH value of the aqueous solution to 10.5; then, add 50µL of 1mol / L ascorbic acid so...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a method for detecting the content of dioxane in children cosmetics. The method comprises the following steps: (1) pretreating a sample to be detected so as to form a sample solution; (2) uniformly mixing the sample solution with prepared nanometer silver colloid so as to form a sample mixed solution; (3) dropping the sample mixed solution on a substrate, and naturally airing, thus obtaining a detection sample; (4) detecting the detection sample by adopting surface-enhanced Raman scattering, thus obtaining an SERS (surface enhanced Raman spectrum) spectrogram of the detection sample; and (5) comparing the obtained SERS spectrogram of the detection sample with an SERS spectrogram of a dioxane standard solution, and calculating so as to obtain the content of the dioxane in the detection sample. The method is simple, convenient and fast to operate and can be used for rapidly carrying out qualitative and quantitative analysis on the content of the dioxane in children cosmetics.

Description

technical field [0001] The invention belongs to the technical field of detection of harmful substances in cosmetics, and in particular relates to a method for detecting dioxane content in children's cosmetics. Background technique [0002] Dioxane, alias dioxane, 1,4-dioxane, colorless transparent liquid, molecular formula is C 4 h 8 o 2 , with a molecular weight of 88.1 and a slight fragrance. Dioxane is slightly toxic and is a prohibited substance in cosmetics. It can enter the body through inhalation, ingestion and percutaneous absorption. It has anesthesia and irritation to the skin, eyes and respiratory system, and has accumulation in the body. Dioxane is not a raw material for production, but a by-product of the production of fatty alcohol polyoxyethylene ether sulfate (AES). It is mainly used as a solvent, emulsifier, detergent, etc. It has a strong affinity for water in the natural environment, and It is not easy to be degraded by organisms, and it has obvious ca...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/65
Inventor 曾念泽陈敏华胡建强陈宇宇张念椿卢剑陈来成
Owner FROG PRINCE (FUJIAN) BABY & CHILD CARE PROD CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com