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Composite hemostatic spray

An analgesic, anti-inflammatory analgesic technology, applied in the field of compound hemostatic spray, can solve the problems of wound necrosis, inaccurate hemostatic effect of hemostatic materials, and high price

Inactive Publication Date: 2014-04-23
李本明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

They each have certain disadvantages: gelatin collagen material comes from cowhide, which is prone to allergies due to species differences, increases the infection rate of wounds, especially for polluted wounds, and the tissue adhesion of gelatin and collagen is poor, It is easy to fall off, and the hemostatic function of both depends on a sufficient amount of platelets and coagulation factors, so the application is limited; fibrin glue is derived from blood, which may cause virus infection; Adverse, it may cause rebleeding, and the hemostatic time is longer, and the effect on rapid bleeding is poor. It is not suitable as a wound hemostatic material alone, so the application is limited; porous zeolite and potato starch will release after absorbing the water in the blood. A lot of heat, leading to local wound necrosis, inflammation, etc.
[0006] Some of these hemostatic materials have inaccurate hemostatic effects, some are expensive, and some are inconvenient to use, all of which have certain defects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A composite hemostatic spray, by weight, the composite hemostatic spray comprises the following components: 0.3 parts of alginic acid, 1.5 parts of hydroxypropyl chitosan, 1 part of N,N-dicarboxymethyl chitosan, indino 1.5 parts of domethacin and 25 parts of distilled water.

[0017] The production process of the hemostatic spray includes the following steps:

[0018] (1) Weigh alginic acid, hydroxypropyl chitosan, N,N-dicarboxymethyl chitosan, and anti-inflammatory analgesic according to the stated ratio, mix and stir evenly;

[0019] (2) The above mixture is added to the proportioned distilled water and stirred evenly, and the composite hemostatic spray is prepared after radiation sterilization.

Embodiment 2

[0021] A composite hemostatic spray, by weight, the composite hemostatic spray comprises the following components: 0.5 parts of alginic acid, 1.5 parts of hydroxypropyl chitosan, 1.5 parts of N,N-dicarboxymethyl chitosan, cloth 2 parts of profen and 30 parts of distilled water.

[0022] The production process of the hemostatic spray includes the following steps:

[0023] (1) Weigh alginic acid, hydroxypropyl chitosan, N,N-dicarboxymethyl chitosan, and anti-inflammatory analgesic according to the stated ratio, mix and stir evenly;

[0024] (2) The above mixture is added to the proportioned distilled water and stirred evenly, and the composite hemostatic spray is prepared after radiation sterilization.

Embodiment 3

[0026] A composite hemostatic spray, by weight, the composite hemostatic spray comprises the following components: 0.5 parts of alginic acid, 1.5 parts of hydroxypropyl chitosan, 3 parts of N,N-dicarboxymethyl chitosan, indino 2 parts of domethacin and ibuprofen, 28 parts of distilled water.

[0027] The production process of the hemostatic spray includes the following steps:

[0028] (1) Weigh alginic acid, hydroxypropyl chitosan, N,N-dicarboxymethyl chitosan, and anti-inflammatory analgesic according to the stated ratio, mix and stir evenly;

[0029] (2) The above mixture is added to the proportioned distilled water and stirred evenly, and the composite hemostatic spray is prepared after radiation sterilization.

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PUM

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Abstract

The invention discloses a composite hemostatic spray of the medical preparation field, the composite hemostatic spray comprises the following components: by weight, 0.3-1 part of alginic acid, 1-3 parts of hydroxypropyl chitosan, 0.5-5 parts of N, N-dicarboxymethyl chitosan, 0.5-5 parts of an anti-inflammatory analgesic and 10-30 parts of distilled water. The composite hemostatic spray has the advantages of being hemostatic, anti-inflammatory, wound healing promoting, anti-sticking, low-price, easy to use, and the like, and can be used for rapid hemostasis of various wounds, surgical wound surfaces, and other surface trauma.

Description

[0001] technical field [0002] The invention relates to a medical preparation, in particular to a composite hemostatic spray. Background technique [0003] Hemorrhage is one of the causes of death in trauma patients, and rapid and effective control of hemorrhage can significantly reduce the mortality rate. Surgery is one of the quick and effective ways to control bleeding, but surgery alone cannot completely control bleeding, and the use of hemostatic materials can greatly reduce the amount of bleeding. [0004] There are many hemostatic materials currently in use, some of which have inaccurate hemostatic effects, some are expensive, some are inconvenient to use, and have certain defects. Surgical bandaging and surgery are one of the quick and effective ways to control bleeding, but simple surgical bandaging and surgical hemostasis cannot completely control bleeding, and there are often undetected or missed incomplete hemostasis, which leads to reoperation or even death of...

Claims

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Application Information

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IPC IPC(8): A61K31/734A61K9/12A61K47/36A61P17/02A61P7/04A61P29/00A61K31/722A61K31/405A61K31/192
Inventor 李本明
Owner 李本明
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