A kind of medicinal dressing hydrogel composite fabric and its preparation method and application

A composite fabric and gel technology, which is applied in medical science, absorbent pads, bandages, etc., can solve the problems of poor mechanical strength and inconvenience, and achieve the effects of avoiding infection, prolonging the drug action cycle, and facilitating wound healing and dressing change

Active Publication Date: 2016-04-27
THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it has the defect of poor mechanical strength, and it often needs to be fixed during application, causing inconvenience

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of medicinal dressing hydrogel composite fabric and its preparation method and application
  • A kind of medicinal dressing hydrogel composite fabric and its preparation method and application
  • A kind of medicinal dressing hydrogel composite fabric and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1: Preparation of medicinal dressing hydrogel composite fabric:

[0034] Dissolve 0.4g of ceric ammonium nitrate, 25mL of N-isopropylacrylamide and 1.2g of dimethylformamide in 0.1mol of nitric acid solution, and bubble with nitrogen;

[0035] Weigh 200 mg of cotton cellulose and use 10 mL of cerium ammonium nitrate solution with a concentration of 20 mM to initiate the reaction for 15 minutes, then blot with a paper towel to remove excess cerium ammonium nitrate solution;

[0036]Then, the cotton cellulose that has been initiated the reaction is dissolved in 5mL of N-isopropylacrylamide and dimethylformamide mixed solution (dissolve 25mL of N-isopropylacrylamide and 1.2g of dimethylformamide as a cross-linking agent in 0.1 After soaking in M ​​nitric acid) for 30min; the cotton cellulose was spread on a dry glass plate, and the obtained substrate was polymerized for 48h under nitrogen conditions. After the complete reaction, the product was washed with water...

Embodiment 2

[0038] Embodiment 2: Preparation of medicinal dressing hydrogel composite fabric:

[0039] Dissolve 0.4g of ceric ammonium nitrate, 25mL of N-isopropylacrylamide and 1.6g of dimethylformamide in 0.1mol of nitric acid solution, and bubble with nitrogen;

[0040] Weigh 200 mg of cotton cellulose and use 10 mL of cerium ammonium nitrate solution with a concentration of 20 mM to initiate the reaction for 15 minutes, then blot with a paper towel to remove excess cerium ammonium nitrate solution;

[0041] Then, the cotton cellulose that has been initiated the reaction is dissolved in 5mL of N-isopropylacrylamide and dimethylformamide mixed solution (dissolve 25mL of N-isopropylacrylamide and 1.2g of dimethylformamide as a cross-linking agent in 0.1 After soaking in M ​​nitric acid) for 30min; cotton cellulose was spread flat on a dry glass plate; the obtained substrate was polymerized for 48h under nitrogen conditions, and the product was washed with water to remove the residue on t...

Embodiment 3

[0043] Embodiment 3: Preparation of medicinal dressing hydrogel composite fabric:

[0044] Dissolve 0.2g ammonium persulfate, 25mL N-isopropylacrylamide and 1.2g dimethylformamide in 0.1mol nitric acid solution, and bubble with nitrogen;

[0045] Weigh 200 mg of cotton cellulose and use 10 mL of cerium ammonium nitrate solution with a concentration of 20 mM to initiate the reaction for 15 minutes, then blot with a paper towel to remove excess cerium ammonium nitrate solution;

[0046] Then, the cotton cellulose that has been initiated the reaction is dissolved in 5mL of N-isopropylacrylamide and dimethylformamide mixed solution (dissolve 25mL of N-isopropylacrylamide and 1.2g of dimethylformamide as a cross-linking agent in 0.1 After soaking in M ​​nitric acid) for 30min; the cotton cellulose was spread on a dry glass plate, and the obtained substrate was polymerized for 48h under nitrogen conditions. After the complete reaction, the product was washed with water to remove the...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

A medical dressing hydrogel composite fabric, and a preparation method therefor and uses thereof. The preparation method comprises: dissolving N-isopropylacrylamide and an initiator by using a solvent, and foaming by using nitrogen; performing an initiation reaction on cotton cellulose in the initiator; soaking the cotton cellulose after the initiation reaction in the mixed solution of N-isopropylacrylamide and dimethylfomamide, and then performing a polymerization reaction in the presence of nitrogen to obtain poly N-isopropyl acrylamide-cotton cellulose; dissolving poly N-isopropyl acrylamide-cotton cellulose together with alginate into distilled water to form hydrogel on the surface; and removing the solvent to obtain the medical dressing hydrogel composite fabric.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations and preparation methods thereof, in particular to a medicinal dressing hydrogel composite fabric and its preparation method and application, which are mainly used for hemostasis and tissue repair of various acute and chronic wounds. Background technique [0002] Local trauma and the resulting bleeding, infection, and ulcer are common injuries. Improper treatment often causes wound inflammation, suppuration, and even ulcer infection. Traditional methods generally use sterile gauze and topical antibiotics for treatment. Traditional gauze dressings can’t keep the wound moist, hinder the epithelialization of tissue cells, and delay wound healing; dressing fibers are easy to fall off, causing foreign body reactions and affecting healing; Destruction of the new epithelium and granulation tissue causes bleeding, which is not only unfavorable for wound healing, but also ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/42A61L15/44A61L15/28C08F251/02C08F220/54C08L51/02C08L5/04C08J3/075
CPCA61L15/28A61L15/44C08B15/06C08F220/54C08F251/02C08L1/08C08L5/04C08L51/02
Inventor 韩晋袁海龙徐和徐平华申宝德
Owner THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap