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Mouthwash containing antimicrobial peptide and sodium copper chlorophyllin and preparation method of mouthwash

A technology of copper chlorophyll sodium salt and antibacterial peptides, applied in the directions of topical antibacterials, oral care, pharmaceutical formulations, etc., can solve the problems of insignificant bacteriostatic effect, unstable chlorophyll, and it is difficult to impart multiple functions to mouthwash, and achieve excellent Antibacterial effect, clear structure, rich effect

Inactive Publication Date: 2014-04-30
GUANGDONG COOWAY BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent application number is 201210484228.3, which discloses a chlorophyll mouthwash and its preparation method, which are used for sterilization, anti-inflammation, breath cleaning, etc., but the added chlorophyll is unstable, and the antibacterial effect is not obvious, so it is difficult to give the mouthwash multiple functions

Method used

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  • Mouthwash containing antimicrobial peptide and sodium copper chlorophyllin and preparation method of mouthwash
  • Mouthwash containing antimicrobial peptide and sodium copper chlorophyllin and preparation method of mouthwash
  • Mouthwash containing antimicrobial peptide and sodium copper chlorophyllin and preparation method of mouthwash

Examples

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Comparison scheme
Effect test

Embodiment 1

[0024] A kind of mouthwash containing antimicrobial peptide and copper chlorophyllin sodium salt, its component mass percentage content is as table 1:

[0025] The composition of the mouthwash containing antimicrobial peptide and sodium copper chlorophyllin in Table 1 Example 1 (parts by mass)

[0026]

[0027] The antimicrobial peptide described therein comes from the antimicrobial peptide DC in patent 200510032743.8, and the activity of the antimicrobial peptide is 5000IU / ml;

[0028] The preparation method of mouthwash is:

[0029] (1) Dissolve 0.01 part of menthol, 0.08 part of borneol and 0.2 part of essence in 8 parts of 95% ethanol by volume;

[0030] (2) Dissolve 2 parts of antimicrobial peptide DC (5000IU / ml), 0.5 parts of copper chlorophyllin sodium salt and 0.2 parts of gallic acid in 20 parts of deionized water, and stir evenly;

[0031] (3) Mix the solution prepared in step (1) with step (2), add deionized water to 100 parts, stir evenly, let stand, and filte...

Embodiment 2

[0033] A kind of mouthwash containing antimicrobial peptide and copper chlorophyllin sodium salt, its component mass percentage content is as table 2:

[0034] The composition of the mouthwash containing antimicrobial peptide and sodium copper chlorophyllin in Table 2 Example 2 (in parts by mass)

[0035]

[0036] The preparation method of mouthwash is:

[0037] (1) Dissolve 0.02 parts of menthol, 0.1 parts of borneol and 0.03 parts of essence in 6 parts of 95% ethanol by volume;

[0038] (2) Dissolve 5 parts of antimicrobial peptide DC (5000IU / ml), 0.1 part of sodium copper chlorophyllin and 0.15 parts of gallic acid in 50 parts of deionized water, and stir well;

[0039] (3) Mix the solution prepared in step (1) with step (2), add deionized water to 100 parts, stir evenly, let stand, and filter to obtain the finished product.

Embodiment 3

[0041] A kind of mouthwash containing antimicrobial peptide and copper chlorophyllin sodium salt, its component mass percentage content is as table 3:

[0042] Composition (in parts by mass) of the mouthwash containing antimicrobial peptide and copper chlorophyllin sodium salt in Table 3 Example 3

[0043]

[0044] The preparation method of mouthwash is:

[0045] (1) Dissolve 0.05 parts of menthol, 0.05 parts of borneol and 0.02 parts of essence in 5 parts of 95% ethanol by volume;

[0046] (2) Dissolve 10 parts of antimicrobial peptide DC (5000IU / ml), 0.001 part of copper chlorophyllin sodium salt and 0.01 part of gallic acid in 50 parts of deionized water in sequence, and stir evenly;

[0047] (3) Mix the solution prepared in step (1) with step (2), add deionized water to 100 parts, stir evenly, let stand, and filter to obtain the finished product.

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Abstract

The invention discloses mouthwash containing antimicrobial peptide and sodium copper chlorophyllin and a preparation method of the mouthwash, and belongs to the field of wash products. The mouthwash containing ntimicrobial peptide and sodium copper chlorophyllin comprises the following components in parts by mass: 2 to 10 parts of antimicrobial peptide, 0.001 to 0.5 part of sodium copper chlorophyllin, 0.01 to 0.05 parts of menthol, 0.01 to 0.2 part of gallic acid, 0.05 to 0.1 part of borneol, 5 to 8 parts of 95% ethanol, 0.02 to 0.2 part of essence, and 100 parts of deionized water. According to the mouthwash, sodium copper chlorophyllin is the product produced by using silkworm excrement as the raw material, has the effects of inhibiting bacteria and deodorizing, and is safe and out of toxic and side effects. The mouthwash can keep the mouth clean, inhibit harmful microbe and deodorization, and is optimal in formula, easy to prepare, and relatively low in cost.

Description

technical field [0001] The invention belongs to the field of rinse products, in particular to a mouthwash containing antibacterial peptide and copper chlorophyllin sodium salt and a preparation method thereof. Background technique [0002] At present, there are many kinds of mouthwashes for oral health care on the market. Search for relevant product descriptions and invention patent disclosure materials, mainly Chinese medicines and chemical reagents. For example, Chinese medicinal materials include mint leaves, lemon leaves, perrin, mugwort, perilla, wild chrysanthemum, neem seeds, tea seed oil, corn oil, etc.; chemical preparations include nidazole, borax, chlorine dioxide, and nano-chitin. A large amount of organic solvents are needed in the extraction of traditional Chinese medicine. It is difficult to determine the active ingredients and specific content of the extract, and its weakness is that there are many production equipment and high cost. [0003] Checking the p...

Claims

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Application Information

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IPC IPC(8): A61K8/64A61K8/49A61K8/368A61Q11/00A61P31/02A61P1/02
Inventor 黄自然陈松彬倪彦艳
Owner GUANGDONG COOWAY BIOTECH CO LTD
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