A gas-electric coupling ion gathering device

Abstract

The invention discloses a pneumoelectric coupling ion focusing device. According to the pneumoelectric coupling ion focusing device, the Venturi and Konda effects are utilized, and the ionization effect and transmission efficiency of spray ions before entering a mass spectrometer feed interface under atmospheric pressure can be effectively improved. According to the front half part of the device, an embedded device comprising an inlet and a main body portion are combined with each other, such that a tapered slit which is communicated with a gas chamber can be formed. Nitrogen is fed at an air inlet, such that the annular air chamber can be filled with high pressure gas, and then, the gas is evenly blown out from the tapered slit, and therefore, high-speed airflow can be formed at an ion funnel and an outlet, it is just the small part of the high-speed nitrogen that drives the movement of gas which is around a pipeline and contains target ions. A series of electrode plates are arranged to form the ion funnel, and the inner diameter of the electrode plates is gradually reduced along the direction of the outlet, and at the same time, DC and RF voltage is applied on the electrode plates. In a test, gas-phase ions can be aggregated through the combination of gas dynamics and an electric field force effect.

Description

technical field [0001] The invention relates to a gathering device for electrospray ionization, which is a device that generates positive or negative ions and gathers and guides them into an ion detector. Electrospray ionization equipment is a device used to improve ion transport efficiency in the early stage. Furthermore, a large number of ions can be transported to the ion detector for further mass spectrometry analysis. Background technique [0002] In the field of analytical chemistry, electrospray ionization mass spectrometer ESI-MS has become the most powerful and widely used tool. It enables higher detection limits to improve mass spectrometry sensitivity, resolution, and mass accuracy. Electrospray ionization ESI is a soft ionization technique. Molecules in solution can be efficiently ionized by this technique and transported into the gas phase at atmospheric pressure. ESI has good applicability for a wide variety of molecules and macromolecules, such as polypept...

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Problems solved by technology

[0011] The invention provides a gathering device for improving ion transport efficiency, which solves the problem of ion expansion caused by Coulomb repulsion, a large loss of effective ions in the first half of the analytical instrument, and noise signals caused by impurity ions and liquid droplets.

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