Pharmaceutical composition for treating hypertension and preparation method thereof

A pharmacy and reserpine technology, applied in the direction of drug combination, pharmaceutical formula, heterocyclic compound active ingredients, etc., can solve the problems affecting the quality of medicines, the instability of dihydralazine sulfate, the instability of dihydralazine sulfate and vitamin B1 and other problems, to achieve the effect of stable components and simple preparation
CN103800367BActive Publication Date: 2017-12-05SHANGHAI SINE PHARMA LAB
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
SHANGHAI SINE PHARMA LAB
Publication Date
2017-12-05

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Abstract

A pharmaceutical composition for treating hypertension and a preparation method thereof. A compound reserpine tablet is provided, the tablet includes reserpine, hydrochlorothiazide, vitamin B6, vitamin B1, calcium pantothenate, magnesium trisilicate, potassium chloride, dihydralazine sulfate, promethazine hydrochloride And a pharmaceutically acceptable carrier, wherein the vitamin B1 exists in the form of coated granules.
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Description

Technical field

[0001] The invention relates to a pharmaceutical composition containing reserpine for treating hypertension and a preparation method thereof, and belongs to the technical field of medicines. Background technique

[0002] Reserpine is an adrenergic nerve inhibitor, which can prevent the storage of mediators in the adrenergic nerve endings and deplete the mediators with a booster effect in the vesicles. Because of its mild antihypertensive effect but long-lasting efficacy, it is generally used in combination with vasodilators and diuretics. Dihydralazine sulfate is a vasodilator that relaxes the smooth muscle of small arteries and reduces peripheral resistance. Hydrochlorothiazide and others are diuretic and antihypertensive drugs. The combined use of reserpine with vasodilators and diuretics has a significant synergistic effect, promotes the reduction of blood pressure, improves the efficacy, and reduces the dose and adverse reactions of each drug; in addition, h...

Claims

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