Application of phellinus igniarius extract in preparation of medicine for treating liver cancer, cervical cancer and breast cancer

A Phellinus extract, a technology for treating liver cancer, applied in the field of medicine, achieving the effects of high extraction efficiency, stable product quality, and convenient operation

Inactive Publication Date: 2014-06-18
安徽省丹皇本草科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although there are new anti-tumor drugs coming out every year in the world, human beings still do n

Method used

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  • Application of phellinus igniarius extract in preparation of medicine for treating liver cancer, cervical cancer and breast cancer
  • Application of phellinus igniarius extract in preparation of medicine for treating liver cancer, cervical cancer and breast cancer
  • Application of phellinus igniarius extract in preparation of medicine for treating liver cancer, cervical cancer and breast cancer

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[0029] Example

[0030] A preparation method of Phellinus igniarius extract includes the following steps:

[0031] (1) Take 10kg of Phellinus igniarius fruiting bodies, pulverize, and extract three times with 95% ethanol reflux (6 times, 5 times, 4 times), each extraction for 2 hours, the extraction temperature is 80 ℃, and the three extracts are combined to obtain Total extract

[0032] (2) After recovering ethanol from the total extract, concentrate to 1.5g crude drug / ml, add distilled water to make a suspension, and then extract with petroleum ether, ethyl acetate and n-butanol in sequence;

[0033] (3) Distill the obtained ethyl acetate extract under reduced pressure, recover the solvent, and concentrate to dryness to obtain 462 g of Phellinus igniarius extract.

[0034] The following experiments prove the anti-tumor activity of the Phellinus igniarius extract of the present invention.

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Abstract

The invention discloses an application of phellinus igniarius extract in preparation of a medicine for treating liver cancer, cervical cancer and breast cancer. A preparation method of the phellinus igniarius extract comprises the following steps of crushing phellinus igniarius solid, then carrying out reflux extraction with 95% alcohol three times, mixing extract liquids obtained by three-time extraction to obtain total extract liquid; (2) recovering alcohol from the total extract liquid, concentrating the total extract liquid without alcohol to a proper amount of extract liquid, adding distilled water to prepare a suspension liquid, and then extracting with petroleum ether, ethyl acetate and n-butyl alcohol for extraction in sequence; and (3) distilling on extracting solution of the ethyl acetate extract liquid in vacuum, recovering a solvent, and concentrating to be dry, thereby obtaining the phellinus igniarius extract. According to the invention, the phellinus igniarius extract obtained by separation and extraction from the phellinus igniarius solid can be effectively used for preparing medicines for treating the liver cancer, the cervical cancer and the breast cancer, has the advantages that the extraction process is simple and easy, the operation is convenient, multiple effective ingredients can be effectively extracted, the extracting efficiency is high and the quality of a product is stable, and has important significance for comprehensive utilization and industrial development of phellinus igniarius resources.

Description

technical field [0001] The invention relates to the application of a phellinus extract in the preparation of medicines for treating liver cancer, cervical cancer and breast cancer, and belongs to the technical field of medicine. Background technique [0002] Liver cancer, cervical cancer, and breast cancer are three common malignant tumors at present, which not only seriously affect the quality of life of patients, but also bring heavy economic and spiritual burdens to families and society, and are also major social problems that plague the world. Treatment and prevention remain among the most pressing issues worldwide. At present, chemical drug therapy is the main means to fight against tumors. Although it has good curative effect, it often causes side effects such as myelosuppression and immune dysfunction, which makes it difficult for patients to adhere to treatment, and the drug resistance of chemotherapeutic drugs during treatment It has become one of the difficult pro...

Claims

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Application Information

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IPC IPC(8): A61K36/06A61P35/00
Inventor 李宁陈刚贾鹏鹏王开金余春富
Owner 安徽省丹皇本草科技有限公司
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