A kind of ibuprofen sodium salt refining device and process

A technology for sodium ibuprofen and a refining device is applied in the field of refining devices for sodium ibuprofen to achieve the effects of large production capacity, low gas flow rate, and easy manufacturing and processing

Active Publication Date: 2016-03-02
山东新华医药化工设计有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is to provide a desulfurization process with short time consumption, high organic matter removal rate, low effluent COD and low cost, which is especially suitable for large-scale industrial production. Device and process for removing organic matter in ibuprofen sodium salt

Method used

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  • A kind of ibuprofen sodium salt refining device and process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] ⑴Add 5000L tap water to the sodium salt dissolving tank ①, raise the temperature to 65°C, add 2.8t ibuprofen sodium salt, and stir for 30 minutes.

[0045] ⑵Introduce the uniformly mixed ibuprofen sodium salt solution into the filter press ②, and filter through the filter screen, the insoluble matter is left on the filter screen of the filter press, and then discharged from the bottom; after the filtrate is absorbed by activated carbon, it enters the sodium salt solution Accept the tank ③ for temporary storage.

[0046] ⑶ The filtrate in the sodium salt solution receiving tank ③ is introduced into the primary condenser ⑦ through the feeding pump ④ and preheated to 85°C.

[0047] ⑷The preheated filtrate enters the stripping tower ⑤ from the top, the filtrate and steam exchange heat in the tower, the organic solvent is brought into the gas phase, and the filtrate from which organic matter is removed enters the stripping receiving tank ⑥ from the bottom of the stripping to...

Embodiment 2

[0051] ⑴ Add 5000L tap water to the sodium salt dissolution tank ①, raise the temperature to 68°C, add 2.9t ibuprofen sodium salt, and stir for 25 minutes.

[0052] ⑵Introduce the uniformly mixed ibuprofen sodium salt solution into the filter press ②, and filter through the filter screen, the insoluble matter is left on the filter screen of the filter press, and then discharged from the bottom; after the filtrate is absorbed by activated carbon, it enters the sodium salt solution Accept the tank ③ for temporary storage.

[0053] ⑶ The filtrate in the sodium salt solution receiving tank ③ is introduced into the primary condenser ⑦ through the feeding pump ④ and preheated to 88°C.

[0054] ⑷The preheated filtrate enters the stripping tower ⑤ from the top, the filtrate and steam exchange heat in the tower, the organic solvent is brought into the gas phase, and the filtrate from which organic matter is removed enters the stripping receiving tank ⑥ from the bottom of the stripping ...

Embodiment 3

[0058] ⑴ Add 5000L tap water to the sodium salt dissolving tank ①, raise the temperature to 70°C, add 3t of ibuprofen sodium salt, and stir for 40 minutes.

[0059] ⑵Introduce the uniformly mixed ibuprofen sodium salt solution into the filter press ②, and filter through the filter screen, the insoluble matter is left on the filter screen of the filter press, and then discharged from the bottom; after the filtrate is absorbed by activated carbon, it enters the sodium salt solution Accept the tank ③ for temporary storage.

[0060] ⑶ The filtrate in the sodium salt solution receiving tank ③ is introduced into the primary condenser ⑦ through the feeding pump ④ and preheated to 90°C.

[0061] ⑷The preheated filtrate enters the stripping tower ⑤ from the top, the filtrate and steam exchange heat in the tower, the organic solvent is brought into the gas phase, and the filtrate from which organic matter is removed enters the stripping receiving tank ⑥ from the bottom of the stripping ...

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Abstract

The present invention adopts the continuous stripping process based on the heat integration method to remove the organic matter in the sodium salt solution, and provides a device and a process for removing the organic matter in the ibuprofen sodium salt: ibuprofen sodium salt and water in the sodium salt Mix in the dissolving tank, dissolve and enter the filter press for separation, the insoluble matter is discharged from the bottom, the separated solution enters the sodium salt solution receiving tank, and the filtrate enters the stripping tower from the top of the tower after being preheated by the primary condenser through the feeding pump , the top product is condensed by the first-stage condenser and the second-stage condenser, and then enters the distributor, and the extracted product flows out from the upper part of the distributor and enters the distillate receiver to collect; the bottom product enters the stripping receiving tank and enters the next process. This process can not only shorten the treatment time, avoid the generation of waste water with high COD content but also re-use the organic matter. The technology has remarkable treatment effect, low operating cost and can generate certain economic benefits, and has high popularization and application value.

Description

technical field [0001] The invention belongs to a technology for producing ibuprofen, in particular to a refining device and technology for ibuprofen sodium salt. Background technique [0002] With the continuous acceleration of our country's industrialization process, the problems of the environment and resources are becoming more and more severe, and the excessive discharge of pollutants has caused serious damage to the ecological environment and is seriously threatening people's normal life. The effective utilization rate of resources is low, resulting in a large waste of resources, which is not conducive to the comprehensive, coordinated and sustainable development of the economy. Modern process industries such as chemicals, pharmaceuticals, and oil refining are large-scale, high-efficiency, and high-profit industries, and they are the pillars of the national economy. However, while they create a lot of wealth, they also often have problems of high material consumption,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07C57/30C07C51/42
CPCC07C51/42C07C57/30
Inventor 张玲寇祖星李英喜
Owner 山东新华医药化工设计有限公司
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