Coaxial electrostatic spinning fibrous scaffold and preparation method thereof
A technology of coaxial electrospinning and fiber support, which is applied in fiber processing, rayon manufacturing, fiber chemical characteristics, etc., to achieve the effects of simple method, prolonged release and absorption time, and easy control.
Active Publication Date: 2014-07-02
PEKING UNIV THIRD HOSPITAL
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Abstract
The invention discloses a coaxial electrostatic spinning fibrous scaffold and a preparation method thereof, belonging to the field of biological tissue engineering. The scaffold comprises an aliphatic polyester shell and a polyvinylpyrrolidone core, not only is safe and non-toxic and has excellent biocompatibility but also has the functions of loading and slowly releasing drugs and/or bioactive factors, and can be widely applied to the field of biological tissue engineering. The invention also provides the preparation method of the coaxial electrostatic spinning fibrous scaffold. The preparation method comprises the step of carrying out coaxial electrostatic spinning by using an aliphatic polyester shell solution and a polyvinylpyrrolidone core solution in the windless environment to prepare a nanoscale electrostatic spinning fibrous scaffold. The nanoscale electrostatic spinning fibrous scaffold is safe and non-toxic, has a relatively high specific surface area and porosity, and has a good slow release function as a carrier of the drugs and/or bioactive factors. The method is simple, is easy to control, and has relatively strong practicability.
Application Domain
Filament/thread formingConjugated synthetic polymer artificial filaments +2
Technology Topic
ElectrospinningChemistry +6
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PUM
Property | Measurement | Unit |
Concentration | 0.14 ~ 0.16 | g/ml |
Concentration | 0.0015 ~ 0.0025 | g/ml |
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