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Drug for treating fungal infection, and preparation method thereof

A fungal infection and drug technology, applied in antibacterial drugs, antifungal agents, drug combinations, etc., can solve the problems of long course of fungal disease, slow effect, toxic and side effects, and achieve strong antibacterial effect, fast curative effect, and small side effects. Effect

Active Publication Date: 2015-06-17
SHENZHEN REDRAY BIOTECHNOLOGY CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, mycocin is the main drug used to treat fungal infections in pet dogs and cats in China, but the current formula still has the problem of slow effect, which cannot effectively solve the problem of long course of fungal diseases, and some drugs have strong toxic side effects

Method used

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  • Drug for treating fungal infection, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] The total amount of raw material is 100 g. Among them, active ingredient 5.86g, mineral oil 24g, propylene glycol 12g, glycerin 10g, DC-34512g, sodium chloride 0.5g, EM-900.5g, R933110g, water 25.14g, of which nystatin 1.2g, Neomycin sulfate 0.4g, polymyxin B sulfate 0.2g, triamcinolone acetonide 0.06g, lidocaine sulfate 4g.

[0036] Preparation Process:

[0037] (1) Propylene glycol, glycerin, mineral oil, and DC-345 are weighed according to the formula ratio, put into the first batching tank in turn, stir and heat at the same time, and stop when heated to 40 degrees;

[0038] (2) Nystatin and triamcinolone acetonide are weighed according to the formula ratio, put into the first batching tank successively, and stir until dissolved;

[0039] (3) Deionized water is weighed according to the formula ratio and put into the second batching tank, neomycin sulfate, polymyxin B sulfate, lidocaine sulfate, and sodium chloride are weighed according to the formula ratio, and put...

Embodiment 2

[0048] The total amount of raw material is 100 g. Among them, 13.4g of active components, 10g of mineral oil, 30g of propylene glycol, 15.1g of glycerin, DC-3453g, 2g of sodium chloride, EM-906g, R93312g, and 18.5g of water, of which nystatin 2g, neosulfate Mycin 0.8g, polymyxin B sulfate 0.5g, triamcinolone acetonide 0.1g, lidocaine sulfate 10g.

[0049] In the preparation process, in step (5), the liquid medicine in the first batching tank needs to be accelerated and stirred until the viscosity reaches 2800 degrees, and the others are the same as in Example 1.

Embodiment 3

[0051] The total amount of raw material is 100 g. Among them, 10.48g of active ingredient, 16g of mineral oil, 18g of propylene glycol, 24g of glycerin, 3.3g of DC-345, 1.3g of sodium chloride, 4.2g of EM-90, 14g of R93314g, 19.72g of water, and 1.4g of nystatin in the active ingredient , neomycin sulfate 0.6g, polymyxin B sulfate 0.4g, triamcinolone acetonide 0.08g, lidocaine sulfate 7g.

[0052] In the preparation process, in step (5), the liquid medicine in the first batching tank needs to be accelerated and stirred until the viscosity reaches 4400 degrees, and the others are the same as in Example 1.

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Abstract

The invention discloses a drug for treating fungal infection of a pet, and a preparation method thereof. The drug comprises the following components in percentage by mass: 5.86-13.4% of active ingredients, 10-24% of mineral oil, 12-30% of propylene glycol, 10-24% of glycerinum, 3-12% of DC-345, 0.5-2% of sodium chloride, 0.5-6% of EM-90, 2-10% of R9331, and the balance of water, wherein the active ingredients comprise 1.2-2.0% of nystatin, 0.4-0.8% of neomycin sulfate, 0.2-0.5% of polymyxin B sulfate, 0.06-0.1% of triamcinolone acetonide, and 4%-10% of lidocaine sulfate. The invention further provides the preparation method of the preparation. The drug is prepared by matching the components through a specific proportion and mainly aims at common skin diseases caused by various fungal infections of pet dogs and pet cats and symptoms of wound infection fester or long-time non-cicatrization caused by trauma.

Description

technical field [0001] The invention relates to the field of medicine for pets, in particular to a medicine for treating fungal infection. Background technique [0002] Pet skin mycoses, or superficial mycoses, refer to fungal diseases caused by fungi infecting the epidermis and its subsidiary structures (hair, horns, claws). There are many types of pathogenic fungi, but the main cause of skin mycosis is Microsporum canis. The clinical features are mainly manifested as circular bald spots with broken hairs on the skin of the pet's head, neck or limbs, covered with gray scales, and in severe cases, tinea spots are connected into one piece. The course of the disease is longer. [0003] At present, mycocin is the main drug used to treat fungal infections in pet dogs and cats in China. However, the current formula still has the problem of slow effect and cannot effectively solve the problem of long course of fungal diseases. Moreover, some drugs have strong toxic and side effe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/12A61P31/10A61P31/04A61P17/02A61P17/04A61P27/16A61P17/00
Inventor 王军军包金旺
Owner SHENZHEN REDRAY BIOTECHNOLOGY CORP LTD
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