Chitosan biological medical glue for promoting human epidermal growth and preparation method of biological medical glue

Abstract

The invention relates to the technical field of medical glue and in particular relates to chitosan biological medical glue for promoting human epidermal growth and a preparation method of the biological medical glue. The chitosan biological medical glue comprises the following raw materials in parts by weight: 10-100g of modified chitosan, 4-20000mg of nano-silver, 1-80g of human-like collagen, 10-400g of glycerol, 0.0001-0.1g of epidermal growth factor, 0.1-200g of viscosity regulator, 0.5-4g of cross-linking agent and the balance of purified water. Main and auxiliary materials take a synergistic effect to form a drug delivering system with a slow release function, thereby improving the availability of active substances; the chitosan biological medical glue is attached close to the uneven wound surface, but the chitosan biological medical glue does not stick to the uneven wound surface. The chitosan biological medical glue is excellent in biocompatibility, strong in antisepsis and anti-inflammation, free of local stimulation and systemic adverse reaction, colorless and transparent, conducive to wound observation, capable of quickly promoting the repair of the wound surface, suppressing and reducing the generation of scar and widely applicable to the treatment of infected wound, operative incisions, all burns, scalds and wounds.

Description

technical field [0001] The invention relates to the technical field of medical glue, in particular to a chitosan biomedical glue for promoting human epidermal growth and a preparation method thereof. Background technique [0002] Superficial abrasion on the skin surface is a common type of trauma in plastic surgery clinical work. It has a large trauma area, is prone to infection, and has poor surgical curative effect; and the conventional dressing change course is long, and the curative effect is not sure; Pigment changes and other sequelae are very harmful to the patient's body and mind. [0003] The traditional treatment of burns and scalds and cosmetic plastic wounds uses bandage therapy, which is inconvenient to operate and difficult to observe the wound healing, poor in infection control, and often causes secondary mechanical damage, which not only brings pain to patients, but also causes wound damage. Potential infection, affecting wound healing. Although there are c...

AI Technical Summary

Problems solved by technology

[0002] Superficial abrasions on the skin surface are a common type of trauma in the clinical work of plastic surgery. They have a large trauma area, are prone to infection, and have poor surgical efficacy; the conventional dressing change course is long and the efficacy is not certain; after healing, the lesions tend to form scars, Pigment changes and other sequelae, causing great harm to the patient's body and mind

[0003] The traditional treatment of burns, scalds and cosmetic plastic wounds uses bandage therapy, which is inconvenient to operate, difficult to observe the wound healing, poor in infection control, and often causes secondary mechanical damage, which not only brings pain to the patient, but also causes damage to the wound. Potential infection, affecting wound healing

Although there are antibacterial dressing products on the market, although they have certain antibacterial, anti-inflammatory, wound-protecting and hemostatic effects, the course of treatment for promoting wound healing and reducing scar formation is long, the curative effect is not satisfactory, and the potential risk is relatively high.