Pharmaceutical composition after chronic nasosinusitis endoscopic sinus surgery

Abstract

The invention discloses a pharmaceutical composition after chronic nasosinusitis endoscopic sinus surgery. The pharmaceutical composition is prepared from the following raw materials (active components) in parts by weight: 12-28 parts of radix scutellariae, 10-20 parts of herba houttuyniae, 10-20 parts of taraxacum, 6-14 parts of Fructus Forsythiae, 6-14 parts of radix bupleuri, 6-14 parts of radix angelicae, 6-14 parts of cocklebur fruit, 6-14 parts of magnolia flower and 4-8 parts of licorice. The invention overcomes the defects of medicines after the existing chronic nasosinusitis endoscopic sinus surgery, and provides a pharmaceutical composition with favorable effects after chronic nasosinusitis endoscopic sinus surgery.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition for chronic sinusitis after endoscopic sinus surgery. Background technique [0002] Chronic sinusitis is a common clinical disease and frequently-occurring disease, mainly manifested as nasal congestion, runny nose, dizziness, headache, hyposmia, inattention, memory loss and other symptoms, seriously affecting the study and life of patients. The pathogenesis of chronic sinusitis is the result of multiple pathogenic factors, including local pathogenic bacterial infection, increased body allergy, microcirculation disorder, deformity of the mouth and nose complex, and low systemic immunity, etc., resulting in nasal mucosal edema, Thickening and polypoid changes, cystic changes, or fibrous tissue hyperplasia, vascular obstruction, glandular atrophy, and mucosal atrophy. Treatment of Western medicine is mainly symptomatic treatment su...

AI Technical Summary

Problems solved by technology

[0003] Endoscopic sinus surgery is currently the most effective method for the treatment of chronic sinusitis and nasal polyps. However, due to the diversity of etiologies and the complexity of pathophysiological outcomes, after endoscopic sinus surgery, there are adverse factors in the operative cavity, such as Infection, granulation, vesicles, mucosal edema at the operation site, impaired mucociliary clearance system function, secretion retention, etc., affect the recovery of the wound and mucosa. For the recovery of the wound and mucosa, postoperative follow-up and comprehensive treatment are important. ring

At present, in clinical practice, normal saline, gentamicin injection and dexamethasone injection are often used to flush the surgical cavity after surgery, which has the advantages of short retention time in the nasal cavity, easy evaporation of the medicinal solution, dry nasal cavity and long-term use of hormones, gentamicin, etc. The application of antibiotics is easy to produce side effects on the human body and other disadvantages, and after use, there are still many patients with postoperative mucosal edema, vesicles, granulation, polyp regeneration, and nasal adhesions, which lead to surgical failure

After nasal endoscopic surgery, in addition to nasal cleaning and dressing changes, intranasal corticosteroids, antibiotics, and antihistamines are routinely used for treatment, but the price is relatively expensive, and long-term medication brings complications and side effects to patients