Pharmaceutical composition after chronic nasosinusitis endoscopic sinus surgery

A technology for chronic sinusitis and a composition, applied in the field of traditional Chinese medicine, can solve the problems of affecting wound surface and mucosal recovery, regeneration of nasal cavity, impaired mucociliary clearance system function, etc.

Active Publication Date: 2014-07-30
同溢堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Endoscopic sinus surgery is currently the most effective method for the treatment of chronic sinusitis and nasal polyps. However, due to the diversity of etiologies and the complexity of pathophysiological outcomes, after endoscopic sinus surgery, there are adverse factors in the operative cavity, such as Infection, granulation, vesicles, mucosal edema at the operation site, impaired mucociliary clearance system function, secretion retention, etc., affect the recovery of the wound and mucosa. For the recovery of the wound and mucosa, postoperative follow-up and comprehensive treatment are important. ring
At present, in clinical practice, normal saline, gentamicin injection and dexamethasone injection are often used to flush the surgical cavity a

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Scutellaria baicalensis 120g, Houttuynia cordata 200g, Dandelion 100g, Forsythia 140g, Bupleurum 60g, Angelica dahurica 140g, Xanthium 60g, Xinyi flower 140g, licorice 40g.

[0028] Weigh the above raw materials, add water and decoct three times, add twice the amount of water each time, decoct for one hour each time, filter, combine the filtrate, and make a decoction according to the conventional process.

Embodiment 2

[0030] Scutellaria baicalensis 280g, Houttuynia cordata 100g, Dandelion 200g, Forsythia 60g, Bupleurum 140g, Angelica dahurica 60g, Xanthium 140g, Xinyi flower 60g, licorice 80g. Weigh the above raw materials according to the ratio, dry, crush, pass through an 80-mesh sieve, soak in 40kg of 50-degree rice wine for 2 months, filter to remove residue, take the supernatant, add the usual amount of penetrant and preservative, shake evenly and serve spray.

Embodiment 3

[0032] Scutellaria baicalensis 160g, Houttuynia cordata 180g, Dandelion 120g, Forsythia 80g, Bupleurum 120g, Angelica dahurica 80g, Xanthium 120g, Xinyi flower 80g, licorice 70g.

[0033] Weigh the above raw materials according to the ratio, add water to decoct twice, add 7 times the amount of water for the first time, decoct for 1.5 hours, add 8 times the amount of water for the second time, decoct for 1.5 hours, combine the decoction, filter, and filtrate Concentrate the extract to a relative density of 1.30 (measured at 70°C), add a conventional amount of sucrose powder, and mix well to make granules.

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PUM

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Abstract

The invention discloses a pharmaceutical composition after chronic nasosinusitis endoscopic sinus surgery. The pharmaceutical composition is prepared from the following raw materials (active components) in parts by weight: 12-28 parts of radix scutellariae, 10-20 parts of herba houttuyniae, 10-20 parts of taraxacum, 6-14 parts of Fructus Forsythiae, 6-14 parts of radix bupleuri, 6-14 parts of radix angelicae, 6-14 parts of cocklebur fruit, 6-14 parts of magnolia flower and 4-8 parts of licorice. The invention overcomes the defects of medicines after the existing chronic nasosinusitis endoscopic sinus surgery, and provides a pharmaceutical composition with favorable effects after chronic nasosinusitis endoscopic sinus surgery.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition for chronic sinusitis after endoscopic sinus surgery. Background technique [0002] Chronic sinusitis is a common clinical disease and frequently-occurring disease, mainly manifested as nasal congestion, runny nose, dizziness, headache, hyposmia, inattention, memory loss and other symptoms, seriously affecting the study and life of patients. The pathogenesis of chronic sinusitis is the result of multiple pathogenic factors, including local pathogenic bacterial infection, increased body allergy, microcirculation disorder, deformity of the mouth and nose complex, and low systemic immunity, etc., resulting in nasal mucosal edema, Thickening and polypoid changes, cystic changes, or fibrous tissue hyperplasia, vascular obstruction, glandular atrophy, and mucosal atrophy. Treatment of Western medicine is mainly symptomatic treatment su...

Claims

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Application Information

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IPC IPC(8): A61K36/78A61P11/02A61P17/02
Inventor 吴任枝黄业武
Owner 同溢堂药业有限公司
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