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A kind of pharmaceutical composition of chronic sinusitis postnasal endoscopy
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A technology for chronic sinusitis and composition, applied in the field of traditional Chinese medicine, can solve problems such as side effects, adhesions, and patient complications in the human body
Active Publication Date: 2015-09-30
黑龙江省普善医疗器械有限公司
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Problems solved by technology
[0003] Endoscopic sinus surgery is currently the most effective method for the treatment of chronic sinusitis and nasal polyps. However, due to the diversity of etiologies and the complexity of pathophysiological outcomes, after endoscopic sinus surgery, there are adverse factors in the operative cavity, such as Infection, granulation, vesicles, mucosal edema at the operation site, impaired mucociliary clearance system function, secretion retention, etc., affect the recovery of the wound and mucosa. For the recovery of the wound and mucosa, postoperative follow-up and comprehensive treatment are important. ring
At present, in clinical practice, normal saline, gentamicin injection and dexamethasone injection are often used to flush the surgical cavity after surgery, which has the advantages of short retention time in the nasal cavity, easy evaporation of the medicinal solution, dry nasal cavity and long-term use of hormones, gentamicin, etc. The application of antibiotics is easy to produce side effects on the human body and other disadvantages, and after use, there are still many patients with postoperative mucosal edema, vesicles, granulation, polyp regeneration, and nasal adhesions, which lead to surgical failure
After nasal endoscopic surgery, in addition to nasal cleaning and dressing changes, intranasal corticosteroids, antibiotics, and antihistamines are routinely used for treatment, but the price is relatively expensive, and long-term medication brings complications and side effects to patients
Method used
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[0026] Weigh the above raw materials, add water and decoct three times, add twice the amount of water each time, decoct for one hour each time, filter, combine the filtrate, and make a decoction according to the conventional process.
[0029]Weigh the above raw materials according to the ratio, dry, crush, pass through an 80-mesh sieve, soak in 40kg of 50-degree rice wine for 2 months, filter to remove residue, take the supernatant, add the usual amount of penetrant and preservative, shake evenly and serve spray.
[0032] Weigh the above raw materials according to the ratio, add water to decoct twice, add 7 times the amount of water for the first time, decoct for 1.5 hours, add 8 times the amount of water for the second time, decoct for 1.5 hours, combine the decoction, filter, and filtrate Concentrate the extract to a relative density of 1.30 (measured at 70°C), add a conventional amount of sucrosepowder, and mix well to make granules.
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Abstract
The invention discloses a pharmaceutical composition for chronic nasosinusitis after endoscopic surgery. The pharmaceutical composition is prepared from following raw materials by weight: 12-28 parts of radix codonopsis, 12-28 parts of prepared rehmannia root, 10-20 parts of Chinese angelica, 10-20 parts of bighead atractylodes rhizome, 6-14 parts of white paeony root, 6-14 parts of pseudo-ginseng and 4-8 parts of licorice. The raw materials are active components. Lack of drugs after the endoscopic surgery for the chronic nasosinusitis at present is overcome. The pharmaceutical composition with good treating effects for the chronic nasosinusitis after the endoscopic surgery is provided.
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