Medicine composition containing multiple vitamins as well as preparation method and detection method of medicine composition
A technology of vitamins and compositions, applied in the field of pharmaceutical compositions containing multiple vitamins and its preparation, can solve the problems of light and heat instability, increase the stability of preparations, increase safety risks, etc.
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Embodiment 1
[0071] Embodiment 1: the pharmaceutical composition (freeze-dried powder injection) containing multivitamins
[0072] formula:
[0073] Name of raw material
Recipe amount
Vitamin A Palmitate
3.3 million IU
Vitamin D 3
2 million IU
Vitamin E
10,000 IU
Vitamin K 1
150mg
Vitamin C
200g
Vitamin B 1
6g
riboflavin sodium phosphate
4.9g
Nicotinamide
40g
Vitamin B 6
6g
Vitamin B 12
5mg
Dexpanthenol
15g
folic acid
600mg
Biotin
60mg
Mannitol
380g
Polyethylene glycol 15-hydroxystearate
75g
sodium hydroxide
Appropriate amount
Add water for injection to
4000g
production
1000 bottles
[0074] Note: Water for injection is removed during freeze-drying
[0075] Preparation:
[0076] 1) Weigh the 15-hydroxypolyethylene glycol stearate of the formula and put it in a st...
Embodiment 2
[0088] Embodiment 2: the pharmaceutical composition (children) containing multivitamin
[0089] formula:
[0090] Name of raw material
Recipe amount
Vitamin A Palmitate
2.3 million IU
Vitamin D 3
400,000 IU
Vitamin E
0.7 million IU
Vitamin K 1
200mg
Vitamin C
80g
Vitamin B 1
1.2g
[0091] riboflavin sodium phosphate
1.4g
Nicotinamide
17g
Vitamin B 6
1g
Vitamin B 12
1mg
Dexpanthenol
5g
folic acid
140mg
Biotin
20mg
Mannitol
380g
15-Hydroxystearic Acid Polyethylene Glycol
75g
sodium hydroxide
Appropriate amount
Add water for injection to
4000g
production
1000 bottles
[0092] Note: Water for injection is removed during freeze-drying
[0093] Preparation:
[0094] 1) Weigh the 15-hydroxypolyethylene glycol stearate of the formula and put it in a ...
Embodiment 3
[0106] Embodiment 3: the pharmaceutical composition containing multivitamins
[0107] formula:
[0108] Name of raw material
Recipe amount
Vitamin A Palmitate
3.3 million IU
Vitamin D 3
200,000IU
Vitamin E
10,000 IU
Vitamin K 1
150mg
Vitamin C
200g
Vitamin B 1
6g
riboflavin sodium phosphate
4.9g
Nicotinamide
40g
Vitamin B 6
6g
Vitamin B 12
5mg
Dexpanthenol
15g
folic acid
600mg
Biotin
60mg
Glycine
380g
Polyethylene glycol 15-hydroxystearate
75g
sodium hydroxide
Appropriate amount
Add water for injection to
4000g
production
1000 bottles
[0109] Note: Water for injection is removed during freeze-drying
[0110] Preparation:
[0111] 1) Weigh the 15-hydroxypolyethylene glycol stearate of the formula and put it in a sterile container, and add the vitamin...
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