Lidocaine compound preparation and aerosol thereof

A technology for lidocaine and compound preparations, applied in the field of medicine, can solve the problems of inability to promote skin self-repair, many active ingredients in western medicine, and lack of film-forming properties, and achieves good film-forming function, good dispersibility, and enhanced stability. sexual effect

Inactive Publication Date: 2014-08-06
MEDONCARE PHARMA CO LTD +1
View PDF5 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Another object of the present invention is to solve the problem that the lidocaine preparations for external use used in the past for antipruritic, bactericidal and anti-inflammatory effects have many western medicine active ingredients, especially the aerosol products are very easy to form fine part

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Lidocaine compound preparation and aerosol thereof
  • Lidocaine compound preparation and aerosol thereof
  • Lidocaine compound preparation and aerosol thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The consumption of each component is:

[0033]

[0034] Preparation method: fully dissolve the above-mentioned powdered lidocaine, aloe extract, and rosemary extract in 3 g of absolute ethanol, then transfer the clear solution into an aerosol aluminum can, and seal the aerosol pump , Press into 25.25g of propellant tetrafluoroethane to obtain a stable medicinal aerosol.

Embodiment 2

[0036] The consumption of each component is:

[0037]

[0038] Preparation method: fully dissolve the above-mentioned powdered lidocaine, aloe extract, and rosemary extract in 3 g of absolute ethanol, then transfer the clear solution into an aerosol aluminum can, and seal the aerosol pump , Press into 23.75g of propellant tetrafluoroethane to obtain a stable medicinal aerosol.

Embodiment 3

[0040] The consumption of each component is:

[0041]

[0042] Preparation method: fully dissolve the above-mentioned powdered lidocaine, chitosan, and rosemary extract in 3 g of absolute ethanol, transfer the clear solution to an aerosol aluminum can, seal the aerosol pump, press Add 23.75g of propellant tetrafluoroethane to obtain a stable medicinal aerosol.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a lidocaine compound preparation, wherein the active component comprises lidocaine. In the compound preparation, an aloe extract and/or chitosan and a rosemary extract as the active components as well as inactive component auxiliary materials are added. Relative to 100 parts by weight of lidocaine, the content of the aloe extract does not exceed 5000 parts by weight, the content of chitosan does not exceed 5000 parts by weight and the content of the rosemary extract does not exceed 200 parts by weight. An aerosol using the lidocaine compound preparation is environment-friendly, stable in physical and chemical properties, good in dispersion and excellent in film-forming property, has the itch-reliving, inflammation-diminishing and sterilizing and self-healing functions, is less in irritation to skins and can be widely applied to infection caused by mild cut, bruise, burn, sunburn and soft tissue injury of skins, mosquito bite, pruritus and miliaria and is used to alleviate symptoms such as local muscular pain, arthralgia and wet.

Description

technical field [0001] The invention belongs to the field of medicine, and specifically relates to a lidocaine compound preparation and an aerosol thereof which can be used for mild skin cuts, abrasions, soft tissue injuries, burns, mosquito bites, pruritus, prickly heat and other diseases. Background technique [0002] Mosquito bites are an important reason for the high incidence of skin diseases in summer. Because mosquito saliva or venom gland leaching fluid contains a variety of antigenic components, these antigens can produce allergic reactions with antibodies after entering the human skin and cause inflammation, causing patients to have symptoms such as redness, swelling, itching, and even localized inflammation in severe cases. Bullae, hemorrhagic necrosis, etc., bring a lot of inconvenience to our normal life. For mosquito bites, abrasions and soft tissue injuries, it is generally believed that debridement should be performed as soon as possible to prevent infection...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/886A61K36/896A61K36/53A61K47/36A61K47/46A61K9/12A61P17/02A61P31/00A61P17/04A61P29/00A61K31/722A61K31/167
Inventor 刘晓忠潘晓红贺伟杰
Owner MEDONCARE PHARMA CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap