Levocarnitine freeze-dried composition for injection and preparation method thereof

A composition and technology for injection, applied in the field of levocarnitine freeze-dried composition for injection and its preparation, and in the field of injections, can solve the problems of increasing the dextrorotatory product of levocarnitine, achieve simple preparation process and avoid degradation , Ease of industrial production
CN103976960AInactive Publication Date: 2014-08-13广东泽盛药业有限公司

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
广东泽盛药业有限公司
Publication Date
2014-08-13
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
Patent Text Reader

Abstract

The invention discloses a levocarnitine freeze-dried composition for injection and a preparation method thereof. The composition contains levocarnitine, fructose diphosphate and lactic acid. Preferably, the weight ratio of levocarnitine to fructose diphosphate is 1:(0.6-2.0). By adding a proper freeze drying propping agent, a stable levocarnitine freeze-dried powder injection is provided. By using the preparation, the transformation of levocarnitine into a dextroisomer side product can be retrained to the maximum extent, degradation of medicaments is avoided, and the stability of the preparation is enhanced.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the technical field of chemical preparations, and in particular relates to an injection, in particular to a levocarnitine freeze-dried composition for injection and a preparation method thereof. Background technique

[0002] L-carnitine, also known as L-carnitine, is an essential natural substance in the energy metabolism of mammals. Its main function is to promote lipid metabolism. For ischemia and hypoxia in various tissues, L-carnitine can improve energy production by increasing energy production. Energy supply of tissues and organs. Other functions of levocarnitine include oxidation of medium-long chain fatty acids, oxidation of fatty acid peroxidase, buffering of the ratio of bound coenzyme A to free coenzyme, and protection from ketones, pyruvate, amino acids ( Including branched-chain amino acids) to generate energy, remove the toxicity of excessive coenzyme A, and regulate the concentration of ammonia in the blood. Le...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More