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Preparation method of salidroside by supercritical CO2 reverse micelles extraction

A salidroside, supercritical technology, applied in the field of natural plant extraction

Inactive Publication Date: 2014-08-13
PROYA COSMETICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method is cumbersome, takes a long time to produce, and the purity of salidroside in the final product is not high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A supercritical CO 2 The preparation method of reverse micelle extraction salidroside adopts the following steps to prepare:

[0017] A: Dry the rhizome of Rhodiola rosea medicinal material in an oven at 50°C, pulverize it with a pulverizer, and obtain a powder of 50-100 meshes, and store it for later use;

[0018] B: Weigh and mix bis(2-ethylhexyl)sodium succinate sulfonate (AOT) and cetyltrimethylammonium bromide (CTAB) according to the mass ratio of 300:1, and then dilute with water to the mass Add 2ml of 0.2mol / L sodium dihydrogen phosphate / disodium hydrogen phosphate buffer solution with a pH of 5.5 to an aqueous solution with a ratio of 3%, adjust the pH of the aqueous solution to 5.8, and store it for later use;

[0019] C: Take by weighing 1000g of the powder prepared by step A and 50g of the aqueous solution prepared by step B according to the mass ratio of 20:1, and put it into a supercritical extraction kettle;

[0020] D: The extraction temperature is 30°C...

Embodiment 2

[0022] A supercritical CO 2 The preparation method of reverse micelle extraction salidroside adopts the following steps to prepare:

[0023] A: Dry the rhizome of Rhodiola rosea medicinal material in an oven at 50°C, pulverize it with a pulverizer, and obtain a powder of 50-100 meshes, and store it for later use;

[0024] B: Weigh and mix di(2-ethylhexyl)sodium succinate sulfonate (AOT) and cetyltrimethylammonium bromide (CTAB) according to the mass ratio of 300:1, and then add water to dilute to the mass To an aqueous solution with a ratio of 4%, add 6ml of 0.2mol / L sodium dihydrogen phosphate / disodium hydrogen phosphate buffer solution with a pH of 5.5, adjust the pH of the aqueous solution to 5.5, and store it for later use;

[0025] C: Take by weighing 1000g of the powder prepared by step A and 50g of the aqueous solution prepared by step B according to the mass ratio of 20:1, and put it into a supercritical extraction kettle;

[0026] D: The extraction temperature is 30...

Embodiment 3

[0028] A supercritical CO 2 The preparation method of reverse micelle extraction salidroside adopts the following steps to prepare:

[0029] A: Dry the rhizome of Rhodiola rosea medicinal material in an oven at 50°C, pulverize it with a pulverizer, and obtain a powder of 50-100 meshes, and store it for later use;

[0030] B: Weigh and mix bis(2-ethylhexyl)sodium succinate sulfonate (AOT) and cetyltrimethylammonium bromide (CTAB) according to the mass ratio of 350:1, and then dilute with water to obtain the mass To an aqueous solution with a ratio of 4%, add 4ml of 0.2mol / L sodium dihydrogen phosphate / disodium hydrogen phosphate buffer solution with a pH of 5.5, adjust the pH of the aqueous solution to 5.7, and store it for later use;

[0031] C: Take by weighing 1000g of powder prepared in A step and 40g of aqueous solution prepared in B step by mass ratio 25:1, pack in the supercritical extraction kettle;

[0032] D: The extraction temperature is 30°C, the extraction pressu...

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PUM

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Abstract

The invention relates to a preparation method of salidroside by supercritical CO2 reverse micelles extraction. The preparation method is characterized by comprising the following steps: A, rhizomes of a rhodiola medicinal material are dried and the dried rhizomes are crushed to obtain a powder of 50-100 meshes; B, bis(2-ethylhexyl)sodium sulfosuccinate and cetyltrimethylammonium bromide are weighed according to the mass ratio of 300-400:1 and then are mixed; an aqueous solution is prepared and pH of the aqueous solution is adjusted to 5.5-5.8 by adding an appropriate amount of pH buffer solution; C, the powder prepared in the step A and the aqueous solution prepared in the step B are weighed according to the mass ratio of 20-30:1 and then are put into a supercritical extraction kettle; and D, extraction temperature is 30-40 DEG C, extraction pressure is 30-45 Mpa and extraction time is 2-3 h; separation pressure in a separation kettle I is 8-10 MPa, temperature is 30-40 DEG C; separation pressure in a separation kettle II is 5-8 MPa and temperature is 20-30 DEG C; and freeze drying is carried out on an extractant obtained from the separation kettle so as to obtain a solid object. The preparation method provided by the invention has beneficial effects of simple extraction technology, high extraction efficiency and high content of salidroside in the extractant.

Description

Technical field [0001] The present invention involves the field of natural plant extraction technology, which specializes in a supercritical CO 2 Preparation method of reddish samuchide extraction of anti -glue beam. Background technique [0002] Red Scenery is a perennial plant -ray or shrub plant. It is a rare wild plant that grows in high -cold and pollution -free zones. It has strong vitality and special adaptability.The main active ingredients of Hongjingtian are Hongjingtianoside, which are widely used in the field of cosmetics.Studies have shown that Hongjingtianoside can delay cell aging, promote cell growth and cell metabolism, inhibit the degenerative changes of the rough surface and mitochondria, inhibit the formation of intracellular lipidin, promote the division of fibrous cells in the leather and its split and itSynthesis, secrete collagen. [0003] Patent CN 101580525 A "Method of Extracting Hongjingtianoside, polysaccharides and tannins from Hongjingtian medicinal...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07H1/08C07H15/18
CPCY02P20/54
Inventor 毕永贤蒋丽刚
Owner PROYA COSMETICS
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