Ammonium chloride cooling patch and preparation method thereof

A technology of ammonium chloride and cooling patches, which is applied in the direction of anti-inflammatory agents, pharmaceutical formulas, chlorine active ingredients, etc., can solve the problems of poor cooling effect of cooling patches, and achieve the effect of maintaining comfort, convenient operation, and obvious cooling effect

Active Publication Date: 2014-08-27
广东达成弘业生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide an ammonium chloride cooling patch, which solves the problem of poor cooling effect of the existing cooling patch

Method used

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  • Ammonium chloride cooling patch and preparation method thereof
  • Ammonium chloride cooling patch and preparation method thereof
  • Ammonium chloride cooling patch and preparation method thereof

Examples

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preparation example Construction

[0034] The preparation method of above-mentioned ammonium chloride cooling patch, concrete steps are as follows:

[0035] Step 1, weighing according to mass percentage: 3% to 6% of polyvinyl alcohol with a degree of polymerization of 1350 to 2050, 10% to 15% of methacrylic acid, 10% to 15% of pressure sensitive adhesive, and 10% to 15% of glycerin 3% to 6% of polylactic acid with a degree of polymerization of 500 to 800, 0.3% to 1% of pregelatinized starch, 9% to 18% of ammonium chloride, and the balance is water. The sum of the mass percentages of the above components is 100%. ;

[0036] Step 2, dissolve the mixture of polyvinyl alcohol, pregelatinized starch and polylactic acid in water and heat it at 70°C to 80°C until it becomes clear, then add methacrylic acid, pressure sensitive adhesive and glycerin after cooling, and stir well After pouring into the mold, cold molding at -15°C to -12°C, adding ammonium chloride after thawing, and cold molding again to obtain a gel;

...

Embodiment 1

[0039] Step 1, weighing according to mass percentage: 0.9 g of polyvinyl alcohol with a polymerization degree of 1950, 3.6 g of methacrylic acid, 3.0 g of pressure-sensitive adhesive, 3.6 g of glycerin, 0.9 g of polylactic acid with a polymerization degree of 600, pregelatinized Starch 0.15g, ammonium chloride 3.6g, water 14.25g;

[0040] Step 2. Dissolve the mixture of polyvinyl alcohol, pregelatinized starch and polylactic acid in water and heat it at 70°C until it becomes clear. After cooling, add methacrylic acid, pressure-sensitive adhesive and glycerin. Stir evenly and pour into In the mold, cold molding is performed at -12°C, and after thawing, ammonium chloride is added, and cold molding is performed again to obtain a gel;

[0041] Step 3, use non-woven fabric as the backing layer, one side of the backing layer is printed with a pattern, and a gel with a thickness of 0.5mm is coated on the side of the backing layer without a pattern as a gel layer, and then the gel lay...

Embodiment 2

[0043] Step 1, weighing according to mass percentage: 1.6g of polyvinyl alcohol with a degree of polymerization of 2050, 4.0g of methacrylic acid, 4.8g of pressure-sensitive adhesive, 6.0g of glycerin, 1.6g of polylactic acid with a degree of polymerization of 500, pregelatinized Starch 0.12g, ammonium chloride 3.6g, water 18.28g;

[0044] Step 2. Dissolve the mixture of polyvinyl alcohol, pregelatinized starch and polylactic acid in water and heat it at 80°C until it becomes clear. After cooling, add methacrylic acid, pressure-sensitive adhesive and glycerin. Stir evenly and pour into In the mold, cold molding is performed at -13°C, after thawing, ammonium chloride is added, and cold molding is performed again to obtain a gel;

[0045]Step 3, use non-woven fabric as the backing layer, one side of the backing layer is printed with a pattern, and a gel layer with a thickness of 0.62mm is coated on the side of the backing layer without a pattern as a gel layer, and then the gel ...

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Abstract

The invention discloses an ammonium chloride cooling patch. The ammonium chloride cooling patch is adhered and connected with a back lining layer, a gel layer, a viscose layer and an anti-adhesion layer from outside to inside in sequence, wherein the gel layer consists of the following components in percentage by weight: 3%-6% of polyvinyl alcohol, 10%-15% of methacrylic acid, 10%-15% of pressure-sensitive adhesive, 10%-15% of glycerol, 3%-6% of polylactic acid, 0.3%-1% of pregelatinized starch, 9%-18% of ammonium chloride, and the balance of water. The invention further discloses a preparation method of the ammonium chloride cooling patch, wherein the preparation method is as follows: mixing the components to prepare gel, coating the gel prepared by mixing the components on the back lining layer as the gel layer, then, coating the viscose layer on the gel layer, and finally coating the anti-adhesion layer on the viscose layer to obtain the ammonium chloride cooling patch. The ammonium chloride cooling patch disclosed by the invention is obvious in cooling effect, firstly takes away local heat of a human body by gasification of moisture in the gel to achieve a partial cooling effect, and secondly takes away much heat by dissolution heat absorption of the ammonium chloride to achieve a dual-cooling effect.

Description

technical field [0001] The invention belongs to the technical field of auxiliary medical applications, and in particular relates to an ammonium chloride cooling patch, and also relates to a preparation method of the ammonium chloride cooling patch. Background technique [0002] Cooling patch is a kind of medical auxiliary preparation, and its application field has been applied to relieve pain, refresh the mind, relax muscles, improve sleep, skin moisturizing and beauty, such as medicine, sporting goods, beauty, daily necessities and other fields. [0003] Most of the existing cooling stickers have a three-layer structure, consisting of a backing layer, a gel layer, and an anti-adhesive layer. The backing layer is made of non-woven fabric, the gel layer is composed of hydrophilic polymer gel, and the anti-adhesive layer is made of transparent plastic film. Starting from the theory of evaporation and heat absorption, it is mostly made of hydrogel, because the evaporation of w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/20A61K9/70A61K47/32A61F7/02A61P29/00
Inventor 沈文张光华高雅博王兰
Owner 广东达成弘业生物科技有限公司
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