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Oral composition

A composition and oral technology, applied in oral care, cosmetic preparations, medical science, etc., can solve the problems not mentioned, and achieve the effect of improving solubility, increasing inhibition effect, and inhibiting precipitation and turbidity

Inactive Publication Date: 2014-11-05
LION CORP
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  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

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Embodiment

[0070] Hereinafter, examples and comparative examples are given to specifically describe the present invention, but the present invention is not limited by the following examples. In the following examples, % means mass % unless otherwise specified.

[0071] In addition, the numerical values ​​in parentheses in polyoxyethylene hydrogenated castor oil and polyoxyethylene alkyl ether represent the average addition mole number of ethylene oxide. In addition, POE in the table|surface is an abbreviation of polyoxyethylene. The pH was measured using a pH meter (model Hm-30S) manufactured by Toa Denpa Kogyo Co., Ltd. immediately after preparing the composition, and was a value at 25° C. for 3 minutes.

[0072] [Example, comparative example]

[0073] Liquid oral compositions of the compositions shown in Tables 1 to 3 were prepared according to the following method. The obtained liquid oral composition was evaluated according to the following method. Moreover, the liquid oral compo...

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Abstract

Provided is an oral composition whereby solubility of ascorbic acid phosphate ester or a salt thereof in a neutral range is improved, sedimentation and turbidity during low-temperature storage are minimized, and a clear appearance is maintained. An oral composition containing (A) ascorbic acid phosphate ester or a salt thereof, into which oral composition are blended: (B) a non-ionic surfactant selected from polyoxyethylene hydrogenated castor oil for which the mean number of moles of E.O. added is 40-100 moles, polyoxyethylene alkyl ether for which the alkyl group is C16-18 and the mean number of moles of E.O. added is 20-40 moles, and polyglyceryl fatty acid ester for which the fatty acid is C12-18; and (C) an aromatic compound selected from isopropyl methylphenol, triclosan, and thymol; (A) / (C) being 1-50 in terms of mass ratio and the pH at 25°C being 6.5-8.0. Furthermore, the oral composition, into which (D) sodium alkylsulphate is also blended.

Description

technical field [0001] The present invention relates to an oral composition containing ascorbyl phosphate or a salt thereof, and more specifically, relates to improving the solubility of ascorbyl phosphate or a salt thereof in a neutral range, suppressing precipitation and turbidity during low-temperature storage, and maintaining clarity Appearance of the oral composition. Background technique [0002] It is known that ascorbic acid plays an important role in the expression of various enzyme activities in a living body and has various physiological activities. In particular, it functions as a coenzyme of proline and lysine hydroxylase and is essential for collagen synthesis. Therefore, it is useful in the prevention and treatment of gingivitis and periodontitis accompanied by collagen destruction, and various ascorbic acid derivatives have been developed in the past, especially ascorbyl phosphate and its salts have attracted attention. [0003] However, when ascorbyl phosp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/67A61K8/34A61K8/46A61K8/86A61Q11/00
CPCA61K8/347A61Q11/00A61K8/86A61K8/676
Inventor 泷沙织野村安雄
Owner LION CORP
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