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A kind of oral ulcer film and preparation method thereof

A technology for oral ulcers and films, which is applied in the field of oral films containing natural active ingredient extracts and their preparation, can solve problems such as affecting diet and daily life, patients' distress, affecting emotions, etc., and achieves effective oral ulcers, complete and smooth appearance , the effect of uniform thickness

Active Publication Date: 2017-08-11
西安康华药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is generally believed that oral ulcers will heal on their own within 7 to 10 days. The problem is that many patients often suffer from repeated symptoms, with ups and downs, which affects diet and daily life, disturbs patients, and even affects emotions.

Method used

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  • A kind of oral ulcer film and preparation method thereof
  • A kind of oral ulcer film and preparation method thereof
  • A kind of oral ulcer film and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] 1.1 Preparation of Bletilla striata extract:

[0037] Weigh 50g of Bletilla striata, crush it into coarse powder, soak for 0.25h, heat and decoct at 95°C for 3 extractions, add 12 times the amount of water for the first time, extract for 1 hour, add 10 times the amount of water for the second time, extract for 1 hour, and extract for the third time Add 8 times the amount of water each time, extract for 0.5h, filter each time, combine the filtrates, concentrate the volume of the combined filtrates to 4 times the weight of Bletilla striata, and filter for later use.

[0038] 1.2 Preparation of stevia leaf extract:

[0039] Weigh 50g of stevia leaves, soak for 0.15h, heat and decoct at 100°C for 3 times, add 16 times the amount of water for the first time, extract for 1 hour, add 12 times the amount of water for the second time, extract for 1 hour, and add 10 times the amount for the third time Measure water, extract for 0.5h, filter each time, combine the filtrates, conc...

Embodiment 2

[0049] 1.1 Preparation of Bletilla striata extract:

[0050] Weigh 30g of Bletilla striata, crush it into coarse powder, soak for 0.55h, heat and decoct at 100°C for 3 extractions, add 11 times the amount of water for the first time, extract for 1 hour, add 9 times the amount of water for the second time, extract for 1 hour, and extract for the third time Add 8 times the amount of water each time, extract for 1 hour, filter each time, combine the filtrates, and concentrate the volume of the filtrates to 5 times the weight of Bletilla striata, g / ml, filter and set aside.

[0051] 1.2 Preparation of stevia leaf extract:

[0052] Weigh 40g of stevia leaves, soak for 0.55h, heat and decoct at 90°C for 3 times, add 17 times the amount of water for the first time, extract for 1.5 hours, add 15 times the amount of water for the second time, extract for 1 hour, and add 10 times the amount for the third time Double the amount of water, extract for 1 hour, filter each time, combine the...

Embodiment 3

[0062] 1.1 Preparation of Bletilla striata extract:

[0063] Weigh 30g of Bletilla striata, crush it into coarse powder, soak for 0.7h, heat and decoct at 100°C for 3 times, add 8 times the amount of water for the first time, extract for 1.5h, add 6 times the amount of water for the second time, extract for 1.2h, For the third time, add 4 times the amount of water, extract for 1 hour, filter each time, combine the filtrates, and concentrate the volume of the filtrates to 3 times the weight of Bletilla striata in g / ml, filter and set aside.

[0064] 1.2 Preparation of stevia leaf extract:

[0065] Weigh 40g of stevia leaves, soak for 0.65h, heat and decoct at 95°C for 3 times, add 10 times the amount of water for the first time, extract for 0.5h, add 10 times the amount of water for the second time, extract for 1.5h, and add 7 times the amount of water, extract for 1.5 hours, filter each time, combine the filtrates, concentrate the volume of the filtrates to 3 times the weight...

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Abstract

The invention relates to an oral film agent containing natural active ingredient extracts and a preparation method of the oral film agent. The dental ulcer film agent is prepared from the following raw materials: 3-10g of polyvinyl alcohol, 1-10g of sodium carboxymethylcellulose, 2-15ml of glycerin, 10-25ml of bletilla extracting solution, 2-10ml of stevia rebaudian extracting solution, 0.1-2g of lidocaine, 0.5-3g of metronidazole, 0.5-3g of borneol, 3-15ml of a 5% vitamin B2 solution, 3-15ml of 5% a vitamin C solution, 3-12ml of 95% ethanol and 22-95 percent of distilled water. The film agent prepared by the invention is complete and smooth in appearance, consistent in thickness and uniform in color, does not have obvious bubbles, is added with natural active ingredients and is very effective on treatment of dental ulcer.

Description

technical field [0001] The invention relates to the technical field of medicine preparation, in particular to an oral film containing extracts of natural active ingredients and a preparation method thereof. Background technique [0002] Oral ulcers are stomatitis, which are ulcers on the cheeks, tongue, palate, gums, etc., with redness, swelling and pain around, and erosion on the ulcer surface. Because the causes of mouth ulcers are different, the symptoms are also different. Clinically divided into catarrhal, aphthous, vesicular, cellulitis, pseudomembranous, ulcerative and papular and other types. No matter what kind of stomatitis, its common clinical symptoms are salivation, loss of appetite or slow food intake, bad breath, oral mucosa flushing, warming, swelling and pain. [0003] When suffering from oral ulcers, ulcers and tissue defects occur on the oral mucosa of the patient; when suffering from papular stomatitis, there are often flat nodules the size of yellow-wh...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/70A61K36/898A61P1/02A61K31/525A61K31/4164A61K31/375A61K31/167A61K31/045
Inventor 孙淑萍李胜利刘侠丁婷李子月
Owner 西安康华药业有限公司
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